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Activates the Jnk signaling pathway. Additionally we are shipping DUSP22 Antibodies (93) and and many more products for this protein.
Showing 8 out of 11 products:
JKAP/DUSP22 is downregulated in T cells of systemic lupus erythematosus nephritis
Data show that dual specificity phosphatase 22 (DUSP22) functions as a tumor suppressor gene in peripheral T-cell lymphomas (PTCL).
findings connect NOTCH1 (show NOTCH1 Proteins), DUSP22, and CCL19 (show CCL19 Proteins)-driven chemotaxis within a single functional network, suggesting that modulation of the homing process may provide a relevant contribution to the unfavorable prognosis associated with NOTCH1 (show NOTCH1 Proteins) mutations in CLL.
findings suggest that CCR8 (show CCR8 Proteins) expression in ALCL is more closely related to the presence of DUSP22 rearrangements than to cutaneous involvement and that the function of CCR8 (show CCR8 Proteins) may extend beyond its skin-homing properties in this disease
Studies suggest that the presence of dual specificity phosphatase 22 (DUSP22) and p63 (show RPE65 Proteins) tumor suppressor protein (show TP53 Proteins) (TP63 (show TP63 Proteins)) rearrangements might be useful to support a diagnosis of anaplastic lymphoma kinase (ALK)-negative anaplastic large cell lymphoma (ALCL).
Report morphologic features of ALK-negative anaplastic large cell lymphomas with DUSP22 gene rearrangements.
Reduced DUSP22 expression was found in colorectal cancer specimens. Low expression level of DUSP22 in stage IV patients had a poor survival outcome
The structure illuminates the molecular basis for substrate binding and may also facilitate the structure-assisted development of DUSP22 inhibitors.
study identified presence of promoter hypermethylation of the DUSP22 gene in Alzheimer's disease(AD); DUSP22 is a likely candidate gene for involvement in the pathogenesis of AD since it inhibits PKA activity and thereby determines TAU phosphorylation status and CREB (show CREB1 Proteins) signaling
Biallelic rearrangements of DUSP22 is found in CD30 (show TNFRSF8 Proteins)-positive T-cell lymphoproliferative disorders.
Dusp22 expression in the adult mouse tissues and organs
cloning and characterization of JKAP, a positive regulator of the JNK (show MAPK8 Proteins) pathway
DSP2 acts as a negative regulator of the IL-6 (show IL6 Proteins)/LIF (show LIF Proteins)/STAT3 (show STAT3 Proteins)-mediated signaling pathway.
Activates the Jnk signaling pathway. Dephosphorylates and deactivates p38 and stress-activated protein kinase/c-Jun N- terminal kinase (SAPK/JNK) (By similarity).
dual specificity phosphatase 22
, dual specificity protein phosphatase 22-A
, dual specificity protein phosphatase 22
, dual specificity phosphatase 22 like
, dual specificity protein phosphatase 22-B
, JNK-stimulating phosphatase 1
, JNK-stimulatory phosphatase-1
, MAP kinase phosphatase x
, homolog of mouse dual specificity phosphatase LMW-DSP2
, low molecular weight dual specificity phosphatase 2
, mitogen-activated protein kinase phosphatase x