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DNAL1 encodes an axonemal dynein light chain which functions as a component of the outer dynein arms complex.
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DNAL1 and MAP4 (show MAP4 Antibodies) may exert their functions in the HIV life cycle at reverse transcription, prior to nuclear translocation.
DNAL1 mutation could help to elucidate the interaction between the DNAL1 to dynein heavy chain and to tubulin (show TUBB Antibodies).
identification of the human (DNAL1) ortholog of the Chlamydomonas LC1-gene; protein (show MAP1B Antibodies) interaction studies demonstrated binding of DNAL1 and DNAH5; DNAL1 considered a candidate for primary ciliary dyskinesia
analysis of the human (DNAL1) and murine (Dnal1) orthologs of the Chlamydomonas LC1 (show MAP1B Antibodies)-gene
This gene encodes an axonemal dynein light chain which functions as a component of the outer dynein arms complex. This complex acts as the molecular motor that provides the force to move cilia in an ATP-dependent manner. The encoded protein is expressed in tissues with motile cilia or flagella and may be involved in the movement of sperm flagella. Alternate splicing results in multiple transcript variants.
dynein light chain 1, axonemal
, axonemal dynein light chain 1