anti-EF-Hand Calcium Binding Domain 4B (EFCAB4B) Antibodies

Ca(2+)-binding protein that plays a key role in store- operated Ca(2+) entry (SOCE) in T-cells by regulating CRAC channel activation. Additionally we are shipping EF-Hand Calcium Binding Domain 4B Proteins (4) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
EFCAB4B 84766 Q9BSW2
EFCAB4B 381812 Q3UP38
EFCAB4B    
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Top anti-EF-Hand Calcium Binding Domain 4B Antibodies at antibodies-online.com

Showing 10 out of 53 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-EFCAB4B Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:312500  Positive Control:  NCI-H226 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-EFCAB4B Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:312500  Positive Control:  NCI-H226 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p) Immunocytochemistry/Immunofluorescence: EFCAB4B Antibody [NBP1-82687] Staining of human cell line A-431 shows positivity in nucleus, nucleoli, cytoplasm & golgi apparatus. Immunohistochemistry-Paraffin: EFCAB4B Antibody [NBP1-82687] - Staining of human stomach shows strong cytoplasmic, membranous and nuclear positivity in glandular cells. 0.1 mL Log in to see 10 to 13 Days
$491.63
Details
Horse Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Cow Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Rabbit Un-conjugated WB EFCAB4B Antibody (N-term)  western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the EFCAB4B antibody detected the EFCAB4B protein (arrow). 400 μL Log in to see 10 to 11 Days
$335.50
Details
Human Rabbit Un-conjugated EIA, WB   0.1 mg Log in to see 8 to 11 Days
$474.10
Details
Human Rabbit Un-conjugated ELISA, IHC, IHC (p), WB Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 11 to 14 Days
$484.00
Details
Human Mouse Un-conjugated IF, WB Western Blot analysis of EFCAB4B expression in transfected 293T cell line by EFCAB4B MaxPab polyclonal antibody.<br><br>Lane 1: MGC4266 transfected lysate(43.45 KDa).<br>Lane 2: Non-transfected lysate.<br> Immunofluorescence of <u>purified</u> MaxPab antibody to EFCAB4B on HeLa cell. [antibody concentration 10 ug/ml] 50 μL Log in to see 11 to 12 Days
$440.00
Details
Human Rabbit Un-conjugated WB Western Blot: EFCAB4B Antibody [NBP1-55340] - Titration: 0.2-1 ug/ml, Positive Control: NCI-H226 cell lysate. 100 μL Log in to see 8 to 11 Days
$485.88
Details

More Antibodies against EF-Hand Calcium Binding Domain 4B Interaction Partners

Human EF-Hand Calcium Binding Domain 4B (EFCAB4B) interaction partners

  1. Results show the characterization of CRACR2A protein which encodes a large Rab GTPase (show RAB6A Antibodies) containing multiple functional domains contrary to small Rab (show HRB Antibodies) GTPases. It was found to play an unexpected role in regulating intracellular signaling pathways important for T cell activation.

  2. GTP binding (show RND2 Antibodies) and prenylation of CRACR2A were associated with its localization near the Golgi and its stability

  3. endothelial cells contain a long variant of CRACR2A which is an EF-hand-containing Rab (show HRB Antibodies) protein that lacks impact on CRAC channels

  4. CRACR2A interacts directly with Orai1 (show ORAI1 Antibodies) and STIM1 (show STIM1 Antibodies), forming a ternary complex that dissociates at elevated Ca(2 (show CA2 Antibodies)+) concentrations; is a key regulator of CRAC channel-mediated SOCE

Mouse (Murine) EF-Hand Calcium Binding Domain 4B (EFCAB4B) interaction partners

  1. GTP binding (show RND2 Antibodies) and prenylation of CRACR2A (show EFCAB4A Antibodies) were associated with its localization near the Golgi and its stability

EF-Hand Calcium Binding Domain 4B (EFCAB4B) Antigen Profile

Protein Summary

Ca(2+)-binding protein that plays a key role in store- operated Ca(2+) entry (SOCE) in T-cells by regulating CRAC channel activation. Acts as a cytoplasmic calcium-sensor that facilitates the clustering of ORAI1 and STIM1 at the junctional regions between the plasma membrane and the endoplasmic reticulum upon low Ca(2+) concentration. It thereby regulates CRAC channel activation, including translocation and clustering of ORAI1 and STIM1. Upon increase of cytoplasmic Ca(2+) resulting from opening of CRAC channels, dissociates from ORAI1 and STIM1, thereby destabilizing the ORAI1-STIM1 complex (By similarity).

Gene names and symbols associated with EFCAB4B

  • calcium release activated channel regulator 2A (CRACR2A) antibody
  • calcium release activated channel regulator 2A (Cracr2a) antibody
  • CRACR2A antibody
  • Gm462 antibody
  • Gm1073 antibody

Protein level used designations for EFCAB4B

CRAC channel regulator 2A , EF-hand calcium-binding domain-containing protein 4B , calcium release-activated calcium channel regulator 2A

GENE ID SPECIES
84766 Homo sapiens
381812 Mus musculus
Selected quality suppliers for anti-EF-Hand Calcium Binding Domain 4B (EFCAB4B) Antibodies
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