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A member of the ELAVL protein family, ELAV-like 3 is a neural-specific RNA-binding protein which contains three RNP-type RNA recognition motifs. Additionally we are shipping ELAVL3 Proteins (7) and many more products for this protein.
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proximal GC box alone confers transcriptional activity of huC promoter in primary Rohon-Beard neurons and the distal GC is required for huC transcription in the full spectrum of spinal cord neurons
HuC expression in neuroblastoma
Loss of Elavl3 is associated with slowly progressive motor deficits leading to severe cerebellar ataxia.
Results suggested that exon 34 of AnkyrinG is an embryonic-stage-preferential exon that should be excluded from mature neurons and that Elavl3 regulates neuronal polarity through alternative splicing of this exon.
This genome-wide approaches identify in vivo targets and functions of nElavl proteins in regulating brain RNA and excitability.
The predominant expression of REST4, HuB/C/D and nPTB in post-mitotic fiber cells, together with miR-124 expression in vertebrate lenses, was shown.
elrC expression was clearly detected in developing Xenopus retina from stage 26 onwards in the differentiating ganglion cell layer.
A member of the ELAVL protein family, ELAV-like 3 is a neural-specific RNA-binding protein which contains three RNP-type RNA recognition motifs. The observation that ELAVL3 is one of several Hu antigens (neuronal-specific RNA-binding proteins) recognized by the anti-Hu serum antibody present in sera from patients with paraneoplastic encephalomyelitis and sensory neuronopathy (PEM/PSN) suggests it has a role in neurogenesis. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
ELAV-like protein 3 , etID309927.3 , elav-related C , embryonic lethal, abnormal vision-related C , Hu antigen C , hu-antigen C , paraneoplastic cerebellar degeneration-associated antigen , paraneoplastic limbic encephalitis antigen 21 , HU-antigen C , ELAV-like 3 , Protein ElrC