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Dental enamel forms the outer cap of teeth and is the hardest substance found in vertebrates.
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Dental enamel forms the outer cap of teeth and is the hardest substance found in vertebrates. This gene encodes the largest protein in the enamel matrix of developing teeth. The protein is involved in the mineralization and structural organization of enamel. Defects in this gene result in amelogenesis imperfect type 1C.
, amelogenesis imperfecta 2, hypocalcification (autosomal dominant)