Enamelin Proteins (ENAM)

Dental enamel forms the outer cap of teeth and is the hardest substance found in vertebrates. Additionally we are shipping Enamelin Antibodies (21) and Enamelin Kits (6) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ENAM 10117 Q9NRM1
ENAM 13801 O55196
Rat ENAM ENAM 289525  
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Top Enamelin Proteins at antibodies-online.com

Showing 2 out of 2 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 70 Days
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days

ENAM Proteins by Origin and Source

Origin Expressed in Conjugate

Mouse (Murine)

More Proteins for Enamelin (ENAM) Interaction Partners

Human Enamelin (ENAM) interaction partners

  1. The ENAM and TNF-alpha (show TNF Proteins) genes were likely associated with caries occurrence in Chinese children. The ENAM rs3796703 CT and TNF-alpha (show TNF Proteins) rs1800629 AG genotypes might be involved in caries susceptibility and protection, respectively.

  2. Among the variants shared with modern humans, two are ancestral (common with apes) and one is the derived enamelin major variant, T648I (rs7671281), associated with a thinner enamel and specific to the Homo lineage.

  3. The study revealed the strong association between rs12640848 marker of ENAM gene and caries susceptibility in primary teeth in children from Poland.

  4. Overrepresentation of the G allele of the enamelin marker was seen in the erosion group compared to the unaffected group.

  5. Screening of ENAM and LAMB3 (show LAMB3 Proteins) genes was performed by direct sequencing of genomic DNA from blood samples.

  6. findings provide useful information for the implication of ENAM gene polymorphism in autosomal-dominant/-recessive amelogenesis imperfecta.

  7. Whole-exome sequencing identified 2 novel heterozygous nonsense mutations in the ENAM gene (c.454G>T p.Glu152* in family 1, c.358C>T p.Gln120* in family 2) in the probands. Affected individuals were heterozygous for the mutation in each family.

  8. 2 exonic SNPs, both changing an amino acid in protein region encoded by exon 10 (p.I648T and p.R763Q), increased caries susceptibility 2.66-fold. findings support ENAM as gene candidate for caries susceptibility.

  9. Associations between TFIP11 (show TFIP11 Proteins) (p=0.02), ENAM (p=0.00001), and AMELX (show AMELX Proteins) (p=0.01) could be seen with caries independent of having MIH or genomic DNA copies of Streptococcus mutans detected by real time PCR in the Brazilian sample.

  10. Mutations in FAM83H and ENAM and related phenotypes were observed in Chinese families with amelogenesis imperfecta.

Mouse (Murine) Enamelin (ENAM) interaction partners

  1. Data suggest that a specific quantity of enamelin is critical for normal enamel formation.

  2. enamelin genotype, which affects enamel integrity, and food hardness influence bodyweight gain in postnatal and young adult mice

  3. The enamelin mutation was associated with earlier forming enamel defects.The study supported the critical involvement of amelogenin (show AMELX Proteins) and enamelin in enamel mineralization.

  4. enamelin acts as an adhesion molecule (show NCAM1 Proteins) and is involved in ameloblast cell differentiation during the early stages of tooth development

  5. The results suggested that Wnt (show WNT2 Proteins)/beta-catenin (show CTNNB1 Proteins) signaling could function in enamelin gene expression by direct interaction through two conserved LEF1 (show LEF1 Proteins) responsive elements on the enamelin gene in ameloblast-like cells.

  6. the amelogenesis imperfecta phenotype is linked to a C > T transition in exon 8 of the enamelin gene

  7. enamelin is essential for proper enamel matrix organization and mineralization

  8. new insights into regulatory mechanisms governing enamelin expression

  9. This study provides new insights into the molecular control of Enam cell- and stage-specific expression.

  10. Mice lacking expression of the AmelX (show AMELX Proteins), Enam and Mmp20 (show MMP20 Proteins) genes have been generated.

Pig (Porcine) Enamelin (ENAM) interaction partners

  1. Results demonstrate that the 32 kDa enamelin has a direct interaction with amelogenin (show AMELX Proteins) in vitro.

Enamelin (ENAM) Protein Profile

Protein Summary

Dental enamel forms the outer cap of teeth and is the hardest substance found in vertebrates. This gene encodes the largest protein in the enamel matrix of developing teeth. The protein is involved in the mineralization and structural organization of enamel. Defects in this gene result in amelogenesis imperfect type 1C.

Gene names and symbols associated with Enamelin Proteins (ENAM)

  • enamelin (ENAM)
  • enamelin (enam)
  • enamelin (Enam)
  • abte protein
  • ADAI protein
  • AI1C protein
  • AIH2 protein

Protein level used designations for Enamelin Proteins (ENAM)

enamelin , amelogenesis imperfecta 2, hypocalcification (autosomal dominant)

471209 Pan troglodytes
482186 Canis lupus familiaris
527075 Bos taurus
100022745 Monodelphis domestica
100271749 Xenopus (Silurana) tropicalis
100349341 Oryctolagus cuniculus
100379596 Cavia porcellus
100398670 Callithrix jacchus
100458880 Pongo abelii
100499197 Anolis carolinensis
100590525 Nomascus leucogenys
10117 Homo sapiens
13801 Mus musculus
289525 Rattus norvegicus
397473 Sus scrofa
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