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EXOG encodes an endo/exonuclease with 5'-3' exonuclease activity. Additionally we are shipping EXOG Antibodies (32) and and many more products for this protein.
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These data indicate that HSV-1 UL12.5 deploys cellular proteins, including ENDOG (show ENDOG Proteins) and EXOG, to destroy mtDNA and contribute to a growing body of literature highlighting roles for ENDOG (show ENDOG Proteins) and EXOG in mtDNA maintenance.
EXOG depletion induces persistent SSBs in the mtDNA, enhances ROS (show ROS1 Proteins) levels, and causes apoptosis in normal cells but not in mt genome-deficient rho0 cells.
ENDOGL1 is a candidate disease-susceptibility gene for type 2 diabetes in a Japanese population
Human endonuclease G-like-1 is a dimeric mitochondrial enzyme that displays 5'-3' exonuclease (show EXO1 Proteins) activity and further differs from EndoG (show ENDOG Proteins) in substrate specificity
This gene encodes an endo/exonuclease with 5'-3' exonuclease activity. The encoded enzyme catalyzes the hydrolysis of ester linkages at the 5' end of a nucleic acid chain. This enzyme is localized to the mitochondria and may play a role in programmed cell death. Alternatively spliced transcript variants have been described. A pseudogene exists on chromosome 18.
nuclease EXOG, mitochondrial
, endonuclease G-like 1
, endo/exonuclease (5'-3'), endonuclease G-like
, endo/exonuclease (5-3), endonuclease G-like
, endo G-like 1
, endonuclease G-like 2
, nuclease EXOG, mitochondrial-like