Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
ELMO1 encodes a member of the engulfment and cell motility protein family. Additionally we are shipping ELMO1 Antibodies (76) and many more products for this protein.
Showing 5 out of 7 products:
ELMO-DOCK1 (show DOCK1 Proteins), a bipartite guanine nucleotide exchange factor (show ARHGEF12 Proteins) complex for the small GTPase (show RACGAP1 Proteins) Rac1, and for the membrane-cytoskeletal linker Ezrin (show EZR Proteins), regulates centriole/basal body migration, docking and spacing.
ELMO1 genetic variation is associated with with type 2 diabetes.
This study revealed the association of the SNP rs1345365 of the ELMO1 gene in a Mexican population
A significant association of the SLC12A3 (show SLC12A3 Proteins) rs11643718 and ELMO1 rs741301 (Single nucleotide Polymorphism) SNPs with diabetic nephropathy in south Indians.
Cdc27 is a novel binding partner of Elmo1.Cdc27-Elmo1 has a cellular role independent from the Elmo-Dock1 (show DOCK1 Proteins)-Rac (show AKT1 Proteins) signal module.
ELMO1 is expressed in rheumatoid arthritis synovium, promotes cell migration and invasion, and regulates Rac1 activity, thereby mediating rheumatoid arthritis pathogenicity.
Src-mediated Y724 phosphorylation in ELMO1 plays a critical role for cell spreading via activation of Rac1, leading to promotion of cell migration.
high ELMO1 expression is an independent negative prognostic factor in normal karyotype (NK) acute myeloid leukemia (show BCL11A Proteins).
For ELMO1 (+9170 G>A), the GG genotype frequency was higher in the diabetic versus control group, but there were no differences between diabetic patients with and without nephropathies.
Thus, Elmo1 and Dock180 (show DOCK1 Proteins) facilitate blood vessel formation by stabilization of the endothelium during angiogenesis.
There is a low frequency rate of the ancestral genotype for the ELMO1 polymorphism rs1345365 in mestizos from the western and southeastern regions of Mexico.
The authors identify ELMO1 as a novel target of TGFbeta (show TGFB1 Proteins) signaling and show that restoration of Tgfbr2 (show TGFBR2 Proteins) results in a complete block of ELMO1 in vivo. Knocking down Elmo1 impairs metastasis of carcinoma cells to the lung, thereby providing insights into the mechanisms of progression of Tgfbr2 (show TGFBR2 Proteins)-deficient invasive transition zone squamous cell carcinoma.
Elmo1 hypermorphs have albuminuria, glomerulosclerosis, and changes in the ultrastructure of the glomerular basement membrane that increase in severity in parallel with the expression of Elmo 1.
Src contributed to tyrosine phosphorylation of ELMO1 at Y720 and Y724 residues, which was crucial for activation of Rac1, followed by the promoting cell adhesion, spreading, and migration.
findings reveal a previously unknown, nonredundant role for Elmo1 in controlling Dock2 levels and Dock2-dependent T cell migration in primary lymphocytes.
regulator of Med31 (show MED31 Proteins), revealing a previously unrecognized link between cytoplasmic signaling proteins and the Mediator complex
Data show that intracellular engulfment protein ELMO1 was required for phagocytosis by DCX (show DCX Proteins)(+) cells.
findings uncover a selective requirement for ELMO1 in Sertoli-cell-mediated removal of apoptotic germ cells and make a compelling case for a relationship between engulfment and tissue homeostasis in vivo
functional studies suggest that BAI1 (show BAI1 Proteins) cooperates with ELMO/Dock180 (show DOCK1 Proteins)/Rac (show AKT1 Proteins) to promote maximal engulfment of apoptotic cells
these results highlight ELMO1 as an important factor for glomerular protection and renal cell survival via decreasing apoptosis, especially under diabetic conditions.
A novel signaling cascade is identified in which ELMO1/DOCK180 (show DOCK1 Proteins) regulates vasculature formation in zebrafish.
This gene encodes a member of the engulfment and cell motility protein family. These proteins interact with dedicator of cytokinesis proteins to promote phagocytosis and cell migration. Increased expression of this gene and dedicator of cytokinesis 1 may promote glioma cell invasion, and single nucleotide polymorphisms in this gene may be associated with diabetic nephropathy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Protein ced-12-like protein
, engulfment and cell motility protein 1
, engulfment and cell motility 1
, engulfment and cell motility protein 1-like
, ced-12 homolog 1
, engulfment and cell motility 1, ced-12 homolog
, engulfment and cell motility 1 splice 1