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May have a role in the cell cycle.. Additionally we are shipping ERH Proteins (15) and ERH Kits (4) and many more products for this protein.
Showing 10 out of 69 products:
Human Monoclonal ERH Primary Antibody for ELISA, WB - ABIN560789
Ishikawa, Ishikawa, Shoji, Imai: A genotoxic stress-responsive miRNA, miR-574-3p, delays cell growth by suppressing the enhancer of rudimentary homolog gene in vitro. in International journal of molecular sciences 2014
Human Polyclonal ERH Primary Antibody for ICC, IF - ABIN4309373
Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells. in Nature methods 2013
Data suggest that ERH interacts directly in nucleus with C-terminal Arg-Gly-rich region of SAFB1/SAFB2 and this multimer co-localizes in insoluble nuclear fraction; binding of ERH reverses inhibition exerted by SAFB1/SAFB2 on SRPK1. (ERH = enhancer of rudimentary homolog protein; SAFB = scaffold attachment factor B; SRPK1 = splicing kinase SR protein kinase-1)
ERH regulation of RNA processing is needed to ensure faithful DNA replication and repair.
REVIEW: recent findings indicate that ERH plays an important role in cell cycle through its mRNA splicing activity and is critically required for genomic stability and cancer cell survival
Identification of amino acid residues of ERH required for its recruitment to nuclear speckles and replication foci
Evolutionarily conserved protein ERH controls CENP-E mRNA splicing and is required for the survival of KRAS mutant cancer cells.
ERH contributes to chromosome alignment at the metaphase plate by localizing CENP-E (show CENPE Antibodies) at kinetochore regions.
ERH may be an important transcription regulator that also functions in the control of cell-cycle progression.
interaction with ERH could block the binding of p21(Cip1/Waf1 (show CDKN1A Antibodies)) by Ciz1 (show CIZ1 Antibodies) in the cell. When ERH and Ciz1 (show CIZ1 Antibodies) are coexpressed in HeLa cells, Ciz1 (show CIZ1 Antibodies) recruits ERH to DNA replication foci
Enhancer of rudimentary homolog (ERH) overexpression may be implicated in the initiation and/or progression of certain human malignancies.
Through expression studies and utilizing a transgenic Msi1 (show MSI1 Antibodies) testis-specific (show AIF1 Antibodies) overexpression model, we have identified 2 unique RNA-binding targets of MSI1 (show MSI1 Antibodies) in spermatogonia, Msi2 (show MSI2 Antibodies) and Erh, and have demonstrated a role for MSI1 (show MSI1 Antibodies) in translational regulation.
May have a role in the cell cycle.
enhancer of rudimentary homolog
, enhancer of rudimentary homolog (Drosophila)
, enhancer of rudimentary homolog A
, enhancer of rudimentary homologue ERH
, preimplantation protein 1