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EPX is a member of the peroxidase gene family and is expressed in eosinophils. Additionally we are shipping EPX Antibodies (122) and EPX Proteins (15) and many more products for this protein.
Showing 6 out of 27 products:
Rat (Rattus) EPX ELISA Kit for Sandwich ELISA - ABIN578634
Boskabady, Tabatabai, Farkhondeh: Inhaled lead affects lung pathology and inflammation in sensitized and control guinea pigs. in Environmental toxicology 2014
Human EPX ELISA Kit for Sandwich ELISA - ABIN423741
Tang, Smith, Salter, Oliveria, Mitchell, Nusca, Howie, Gauvreau, OByrne, Sehmi: Allergen-Induced Increases in Interleukin-25 and Interleukin-25 Receptor Expression in Mature Eosinophils from Atopic Asthmatics. in International archives of allergy and immunology 2016
tyrosine phosphorylation of PMR1 (show ATP2C1 ELISA Kits) is required for the targeting and degradation of polyribosome-bound substrate mRNA
peroxidase enzymes, like MPO (show MPO ELISA Kits) and EPO (show EPO ELISA Kits), may play a fundamental role in inhibiting RANKL (show TNFSF11 ELISA Kits)-induced osteoclast differentiation at inflammatory sites of bone fracture and injury.
Both MPO (show MPO ELISA Kits) and EPO (show EPO ELISA Kits) are causatively involved in breast cancer progression and identified as potential therapeutic targets whereby specific novel inhibitors may reduce tumor growth and limit the occurrence of metastasis.
The main significance of this work is the discovery of EPO (show EPO ELISA Kits) as a novel ligand for the HER2 (show ERBB2 ELISA Kits) receptor. Following HER2 (show ERBB2 ELISA Kits) activation, EPO (show EPO ELISA Kits) induces activation of FAK (show PTK2 ELISA Kits) and subsequent activation of beta1-integrin, via inside-out signaling. This complex results in downstream activation of ERK1/2 (show MAPK1/3 ELISA Kits) and a sustained up regulation of both MUC4 (show MUC4 ELISA Kits) and the HER2 (show ERBB2 ELISA Kits) receptor
EPO (show EPO ELISA Kits)-mediated protein carbamylation is promoted during allergen-induced asthma exacerbation, and can both modulate immune responses and trigger a cascade of many of the inflammatory signals present in asthma.
there is a strong association in a given patient between both nasal and pharyngeal EPX levels and the eosinophil percentage of induced sputum.
Myeloperoxidase (show MPO ELISA Kits) and eosinophil peroxidase are readily internalized by HUVEC cells where they promote cellular proliferation, migration, invasion, and stimulate angiogenesis both in vitro and in vivo.
A preferential role of EPO (show EPO ELISA Kits) signaling via a specific surface receptor that leads to neural plasticity.
Eosinophil peroxidase in sputum represents a unique biomarker of airway eosinophilia.
report the prevalence of a common SNP in the eosinophil protein x/eosinophil-derived neurotoxin (show RNASE2 ELISA Kits) (EPX/EDN (show RNASE2 ELISA Kits), RNase2 (show RNASE2 ELISA Kits)) and the association with the cellular contents of EPX/EDN (show RNASE2 ELISA Kits) and ECP (show ECP ELISA Kits)
Polymorphisms of EPX and ECP (show ECP ELISA Kits) are associated to inflammatory bowel disease in an age and gender dependent manne.
The expression of MBP-1 and EPX was also required for induced lung expression of IL-4 (show IL4 ELISA Kits)/IL-13 (show IL13 ELISA Kits) in each setting and, in turn, the induced pulmonary remodeling events and lung dysfunction.
The absence of MBP-1 and EPX promoted a concomitant loss of eosinophil lineage-committed progenitors in the marrow, identifying a specific blockade in eosinophilopoiesis as the causative event.
HER2 (show ERBB2 ELISA Kits) was identified as a novel mediator of eosinophil peroxidase signaling. Eosinophil peroxidase, at noncytotoxic levels, can drive cell-cycle progression and proliferation.
Host protection against Brugia pahangi infections was unimpaired in mice deficient in eosinophil peroxidase.
Mice deficient for either eosinophil peroxidase or major basic protein on the 129/SvJ background developed significantly higher worm burdens than wild-type mice.
post-translational tyrosine nitration of eosinophil granule toxins mediated by eosinophil peroxidase
The activities of EPO (show EPO ELISA Kits), an eosinophilic secondary granule protein, do not affect the development of allergic pulmonary pathologies in the mouse lung at levels comparable to those observed in humans with asthma.
This gene is a member of the peroxidase gene family and is expressed in eosinophils. The encoded precursor protein is processed into covalently attached heavy and light chains to form the mature enzyme, which functions as an oxidant. The enzyme is released at sites of parasitic infection or allergen stimulation to mediate lysis of protozoa or parasitic worms. The gene is found in a cluster of three peroxidase genes at chromosome 17q23. Mutations in this gene result in eosinophil peroxidase deficiency.
, polysomal ribonuclease 1
, eosinophil peroxidase-like