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EI24 has higher expression in p53-expressing cells than in control cells and is an immediate-early induction target of p53-mediated apoptosis. Additionally we are shipping Etoposide Induced 2.4 Antibodies (58) and many more products for this protein.
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EI24 is an essential player in ubiquitin-proteasome system-autophagy crosstalk via degradation of RING E3 ligases.
Low EI24 and high IGF-1R (show IGF1R Proteins) expressions in lung cancer patients.
Ei24 is a novel E2F1 (show E2F1 Proteins) target gene contributing to the survival of p53 (show TP53 Proteins)-deficient cells upon UVC irradiation and thus may have a potential significance as a therapeutic target of certain chemotherapy for treating p53 (show TP53 Proteins)-deficient tumors.
our data suggest that inactivation of EI24 and CHEK1 (show CHEK1 Proteins) through two independent mechanisms contributes to the development of CACX.
LOH11CR2A, PIG8 (show CEP57 Proteins) and CHEK1 (show CHEK1 Proteins) are candidate tumor suppressor genes associated with breast carcinoma and have significant clinical as well as prognostic importance.
Ei24 is a regulator of the RINCK1-PKCalpha (show PKCa Proteins)-EGFR (show EGFR Proteins) signaling pathway in the development of skin-cancer.
This gene has higher expression in p53-expressing cells than in control cells and is an immediate-early induction target of p53-mediated apoptosis. The protein encoded by this gene contains six putative transmembrane domains and may suppress cell growth by inducing apoptotic cell death through the caspase 9 and mitochondrial pathways. This gene is located on human chromosome 11q24, a region frequently altered in cancers. Alternative splicing results in two transcript variants encoding different isoforms.
ectopic P-granules autophagy protein 4 homolog
, etoposide induced 2.4 mRNA
, etoposide-induced protein 2.4 homolog
, p53-induced gene 8 protein
, tumor protein p53 inducible protein 8
, etoposide-induced protein 2.4