Etoposide Induced 2.4 Proteins (EI24)

EI24 has higher expression in p53-expressing cells than in control cells and is an immediate-early induction target of p53-mediated apoptosis. Additionally we are shipping Etoposide Induced 2.4 Antibodies (61) and and many more products for this protein.

list all proteins Gene Name GeneID UniProt
EI24 9538 O14681
Rat EI24 EI24 300514 Q4KM77
EI24 13663 Q61070
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Top Etoposide Induced 2.4 Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 50 to 55 Days
$5,262.31
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 50 to 55 Days
$7,493.38
Details
Wheat germ Human GST tag 2 μg Log in to see 11 to 12 Days
$338.33
Details

EI24 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for Etoposide Induced 2.4 (EI24) Interaction Partners

Human Etoposide Induced 2.4 (EI24) interaction partners

  1. EI24 is an essential player in ubiquitin-proteasome system-autophagy crosstalk via degradation of RING E3 ligases.

  2. Low EI24 expression is associated with triple negative breast cancer.

  3. Low EI24 and high IGF-1R expressions in lung cancer patients.

  4. Findings establish EI24 as a critical suppressor of tumor progression.

  5. Ei24 can bind specifically to IMPbeta1 and IMPalpha2 to impede their normal role in nuclear import.

  6. Ei24 is a novel E2F1 target gene contributing to the survival of p53-deficient cells upon UVC irradiation and thus may have a potential significance as a therapeutic target of certain chemotherapy for treating p53-deficient tumors.

  7. our data suggest that inactivation of EI24 and CHEK1 through two independent mechanisms contributes to the development of CACX.

  8. LOH11CR2A, PIG8 and CHEK1 are candidate tumor suppressor genes associated with breast carcinoma and have significant clinical as well as prognostic importance.

  9. identify the EI24/PIG8 status as a potentially new prognostic marker of chemotherapy responsiveness

Mouse (Murine) Etoposide Induced 2.4 (EI24) interaction partners

  1. Findings establish EI24 as a critical suppressor of tumor progression.

  2. Ei24 can bind specifically to IMPbeta1 and IMPalpha2 to impede their normal role in nuclear import.

  3. Ei24 is a novel E2F1 target gene contributing to the survival of p53-deficient cells upon UVC irradiation and thus may have a potential significance as a therapeutic target of certain chemotherapy for treating p53-deficient tumors.

  4. Ei24 is a regulator of the RINCK1-PKCalpha-EGFR signaling pathway in the development of skin-cancer.

  5. Ei24 is an essential autophagy gene and plays an important role in clearance of aggregate-prone proteins in neurons and hepatocytes.

  6. Studies identified 61 novel potential mEi24 interacting proteins.

  7. identify the EI24/PIG8 status as a potentially new prognostic marker of chemotherapy responsiveness

Etoposide Induced 2.4 (EI24) Protein Profile

Protein Summary

This gene has higher expression in p53-expressing cells than in control cells and is an immediate-early induction target of p53-mediated apoptosis. The protein encoded by this gene contains six putative transmembrane domains and may suppress cell growth by inducing apoptotic cell death through the caspase 9 and mitochondrial pathways. This gene is located on human chromosome 11q24, a region frequently altered in cancers. Alternative splicing results in two transcript variants encoding different isoforms.

Gene names and symbols associated with Etoposide Induced 2.4 Proteins (EI24)

  • EI24, autophagy associated transmembrane protein (EI24)
  • EI24, autophagy associated transmembrane protein (Ei24)
  • etoposide induced 2.4 mRNA (Ei24)
  • AA536736 protein
  • AI115355 protein
  • EPG4 protein
  • PIG8 protein
  • TP53I8 protein

Protein level used designations for Etoposide Induced 2.4 Proteins (EI24)

ectopic P-granules autophagy protein 4 homolog , etoposide induced 2.4 mRNA , etoposide-induced protein 2.4 homolog , p53-induced gene 8 protein , tumor protein p53 inducible protein 8 , etoposide-induced protein 2.4

GENE ID SPECIES
9538 Homo sapiens
300514 Rattus norvegicus
532527 Bos taurus
13663 Mus musculus
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