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EXOSC2 Proteins

(Exosome Component 2 (EXOSC2))
Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. The RNA exosome may be involved in Ig class switch recombination (CSR) and/or Ig variable region somatic hypermutation (SHM) by targeting AICDA deamination activity to transcribed dsDNA substrates. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA. The catalytic inactive RNA exosome core complex of 9 subunits (Exo-9) is proposed to play a pivotal role in the binding and presentation of RNA for ribonucleolysis, and to serve as a scaffold for the association with catalytic subunits and accessory proteins or complexes. EXOSC2 as peripheral part of the Exo-9 complex stabilizes the hexameric ring of RNase PH-domain subunits through contacts with EXOSC4 and EXOSC7.
EXOSC2 Protein (AA 71-160) (GST tag) EXOSC2 Protein (AA 71-160) (GST tag) EXOSC2 Protein (AA 71-160) (GST tag) (ABIN1353235)

EXOSC2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP

EXOSC2 Protein (AA 1-293) (His tag) EXOSC2 Protein (AA 1-293) (His tag) EXOSC2 Protein (AA 1-293) (His tag) (ABIN3136691)

Crystallography grade EXOSC2 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys

EXOSC2 Protein (AA 1-293) (His tag) (ABIN7409152)

EXOSC2 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % WB, SDS, Imm, PC

EXOSC2 Proteins by Grade

Find EXOSC2 Proteins with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

EXOSC2 Proteins by Origin

Find EXOSC2 Proteins for a variety of species such as anti-Human EXOSC2, anti-Cow EXOSC2, anti-Mouse EXOSC2. The species listed below are among those available. Click on a link to go to the corresponding products.

EXOSC2 Proteins by Source

Here you will find EXOSC2 Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

EXOSC2 Proteins by Protein Type

Here you can find EXOSC2 Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

EXOSC2 Proteins by Application

Find EXOSC2 Proteins validated for a specific application such as ELISA, WB, SDS, AP. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular EXOSC2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1353235
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3136691
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7409152
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2731213
Quantity 20 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN6122664
Quantity 50 μg
Datasheet Datasheet
Reactivity Cow
Source Yeast
Validations
Cat. No. ABIN1622739
Quantity 1 mg
Datasheet Datasheet
Reactivity Schizosaccharomyces pombe
Source Yeast
Validations
Cat. No. ABIN1617165
Quantity 1 mg
Datasheet Datasheet
Reactivity Saccharomyces cerevisiae
Source Yeast
Validations
Cat. No. ABIN1478145
Quantity 1 mg
Datasheet Datasheet

Aliases for EXOSC2 Proteins

exosome component 2 (EXOSC2) Proteins
exosome component 2 (exosc2) Proteins
exosome component 2 (Bm1_33895) Proteins
exosome component 2 (PTRG_00114) Proteins
exosome component 2 (Exosc2) Proteins
exosome component 2 L homeolog (exosc2.L) Proteins
EXOSC2 Proteins
exosc2 Proteins
fa97b01 Proteins
hRrp4p Proteins
MGC97533 Proteins
p7 Proteins
RRP4 Proteins
Rrp4 Proteins
Rrp4p Proteins
wu:fa97b01 Proteins
zgc:110117 Proteins
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