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The protein encoded by FKBP2 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. Additionally we are shipping FK506 Binding Protein 2, 13kDa Antibodies (26) and many more products for this protein.
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observed changes in activity of six rER-resident PPIases, cyclophilin B (show PPIB Proteins) (encoded by the PPIB (show PPIB Proteins) gene), FKBP13 (FKBP2), FKBP19 (FKBP11 (show FKBP11 Proteins)), FKBP22 (FKBP14 (show FKBP14 Proteins)), FKBP23 (FKBP7 (show FKBP7 Proteins)), and FKBP65 (FKBP10 (show FKBP10 Proteins)), due to posttranslational modifications of proline residues in the substrate.
FKBP13 and FK506 have roles in vesicular trafficking, influencing ADP-ribosylation factor (show ARF1 Proteins) activity through their guanine nucleotide-exchange proteins
The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is thought to function as an ER chaperone and may also act as a component of membrane cytoskeletal scaffolds. Multiple alternatively spliced variants, encoding the same protein, have been identified.
13 kDa FK506-binding protein
, 13 kDa FKBP
, FK506-binding protein 2 (13kD)
, PPIase FKBP2
, immunophilin FKBP13
, peptidyl-prolyl cis-trans isomerase FKBP2
, proline isomerase
, rapamycin-binding protein
, FK506-binding protein 2
, FK506 binding protein 2, 13kDa