FXYD5 ELISA Kits
FXYD5 encodes a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids.
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FXYD5 ELISA Kit (FXYD Domain Containing Ion Transport Regulator 5) ELISA Kit
FXYD5 Antigen Profile
Protein Summary
This gene encodes a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The approved human gene nomenclature for the family is FXYD-domain containing ion transport regulator. Mouse FXYD5 has been termed RIC (Related to Ion Channel). FXYD2, also known as the gamma subunit of the Na,K-ATPase, regulates the properties of that enzyme. FXYD1 (phospholemman), FXYD2 (gamma), FXYD3 (MAT-8), FXYD4 (CHIF), and FXYD5 (RIC) have been shown to induce channel activity in experimental expression systems. Transmembrane topology has been established for two family members (FXYD1 and FXYD2), with the N-terminus extracellular and the C-terminus on the cytoplasmic side of the membrane. This gene product, FXYD5, is a glycoprotein that functions in the up-regulation of chemokine production, and it is involved in the reduction of cell adhesion via its ability to down-regulate E-cadherin. It also promotes metastasis, and has been linked to a variety of cancers. Alternative splicing results in multiple transcript variants.
Gene names and symbols associated with FXYD5
- FXYD domain containing ion transport regulator 5 (FXYD5) antibody
- FXYD domain-containing ion transport regulator 5 (Fxyd5) antibody
- DYSAD antibody
- EF-8 antibody
- FXYD5 antibody
- IWU1 antibody
- KCT1 antibody
- Oit2 antibody
- PRO6241 antibody
- RIC antibody
Protein level used designations for FXYD5
FXYD domain-containing ion transport regulator 5 , FXYD domain containing ion transport regulator 5 , dysadherin , keratinocytes associated transmembrane protein 1 , ion channel homolog RIC , oncoprotein induced transcript 2 , oncoprotein-induced protein 2
GENE ID | SPECIES |
---|---|
505584 | Bos taurus |
744650 | Pan troglodytes |
53827 | Homo sapiens |
18301 | Mus musculus |
60338 | Rattus norvegicus |
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