FXYD5 ELISA Kits

FXYD5 encodes a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids.

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2 Products
Pre-coated, Samples: Serum, Plasma, Tissue Homogenate, Cell Lysate
ReactivityHuman
Detection MethodColorimetric, Sandwich ELISA
Detection Range39-2500 pg/mL
Order details Cat. No. ABIN839357
$910.56
Plus shipping costs $45.00
Delivery in 15 to 18 Business Days
Pre-coated, Samples: Serum, Plasma, Tissue Homogenate
ReactivityMouse (Murine)
Detection MethodColorimetric, Sandwich ELISA
Detection Range0.312-20 ng/mL
Order details Cat. No. ABIN815100
$910.56
Plus shipping costs $45.00
Delivery in 15 to 18 Business Days
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FXYD5 Antigen Profile

Protein Summary

This gene encodes a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The approved human gene nomenclature for the family is FXYD-domain containing ion transport regulator. Mouse FXYD5 has been termed RIC (Related to Ion Channel). FXYD2, also known as the gamma subunit of the Na,K-ATPase, regulates the properties of that enzyme. FXYD1 (phospholemman), FXYD2 (gamma), FXYD3 (MAT-8), FXYD4 (CHIF), and FXYD5 (RIC) have been shown to induce channel activity in experimental expression systems. Transmembrane topology has been established for two family members (FXYD1 and FXYD2), with the N-terminus extracellular and the C-terminus on the cytoplasmic side of the membrane. This gene product, FXYD5, is a glycoprotein that functions in the up-regulation of chemokine production, and it is involved in the reduction of cell adhesion via its ability to down-regulate E-cadherin. It also promotes metastasis, and has been linked to a variety of cancers. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with FXYD5

  • FXYD domain containing ion transport regulator 5 (FXYD5) antibody
  • FXYD domain-containing ion transport regulator 5 (Fxyd5) antibody
  • DYSAD antibody
  • EF-8 antibody
  • FXYD5 antibody
  • IWU1 antibody
  • KCT1 antibody
  • Oit2 antibody
  • PRO6241 antibody
  • RIC antibody

Protein level used designations for FXYD5

FXYD domain-containing ion transport regulator 5 , FXYD domain containing ion transport regulator 5 , dysadherin , keratinocytes associated transmembrane protein 1 , ion channel homolog RIC , oncoprotein induced transcript 2 , oncoprotein-induced protein 2

GENE ID SPECIES
505584 Bos taurus
744650 Pan troglodytes
53827 Homo sapiens
18301 Mus musculus
60338 Rattus norvegicus