Family with Sequence Similarity 175, Member B (FAM175B) ELISA Kits

Component of the BRISC complex, a multiprotein complex that specifically cleaves 'Lys-63'-linked ubiquitin. Additionally we are shipping Family with Sequence Similarity 175, Member B Antibodies (16) and Family with Sequence Similarity 175, Member B Proteins (5) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Rat FAM175B FAM175B 293570  
Anti-Human FAM175B FAM175B 23172 Q15018
Anti-Mouse FAM175B FAM175B 109359 Q3TCJ1
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More ELISA Kits for Family with Sequence Similarity 175, Member B Interaction Partners

Human Family with Sequence Similarity 175, Member B (FAM175B) interaction partners

  1. In late S/G2 (show STRN3 ELISA Kits) phase, the DNA damage-responsive E3 ligase RNF8 (show RNF8 ELISA Kits) conjugates K63-linked ubiquitin chains to tankyrase 1 (show TNKS ELISA Kits), while in G1 phase such ubiquitin chains are removed by BRISC, an ABRO1/BRCC36 (show BRCC3 ELISA Kits)-containing deubiquitinase complex.

  2. KIAA0157 allosterically activates a cognate deubiquitinating enzyme (DUB) partner and implicates super dimerization as a new regulatory mechanism underlying BRCC36 (show BRCC3 ELISA Kits) DUB activity.

  3. ABRO1 is a novel p53 (show TP53 ELISA Kits) regulator that plays an important role in tumor suppression and the DNA damage response

  4. Study identified Abro1 as a specific interactor of THAP5, a zinc finger transcription factor that is involved in G2/M control and apoptosis.

Mouse (Murine) Family with Sequence Similarity 175, Member B (FAM175B) interaction partners

  1. Data shows that the expression of Abro1 protein substantially increased (at least three-fold) in the hearts of mice that underwent MI/R compared to sham operated controls.

Family with Sequence Similarity 175, Member B (FAM175B) Antigen Profile

Antigen Summary

Component of the BRISC complex, a multiprotein complex that specifically cleaves 'Lys-63'-linked ubiquitin. May act as a central scaffold protein that assembles the various components of the BRISC complex (By similarity).

Gene names and symbols associated with FAM175B

  • abraxas 2, BRISC complex subunit (Abraxas2) antibody
  • abraxas 2, BRISC complex subunit (abraxas2) antibody
  • family with sequence similarity 175 member B (FAM175B) antibody
  • abraxas 2, BRISC complex subunit L homeolog (abraxas2.L) antibody
  • abraxas 2, BRISC complex subunit (ABRAXAS2) antibody
  • BRISC complex subunit (Abraxas2) antibody
  • AA589499 antibody
  • Abro1 antibody
  • AI853413 antibody
  • C430003P19Rik antibody
  • KIAA0157 antibody
  • MGC83343 antibody
  • RGD1308918 antibody

Protein level used designations for FAM175B

BRISC complex subunit Abro1 , Abraxas brother protein 1 , Protein FAM175B , family with sequence similarity 175, member B , abraxas brother 1 , abraxas brother protein 1

GENE ID SPECIES
293570 Rattus norvegicus
394764 Xenopus (Silurana) tropicalis
423954 Gallus gallus
447750 Xenopus laevis
23172 Homo sapiens
109359 Mus musculus
510233 Bos taurus
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