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May act as a defensin against invading fungal microorganisms.. Additionally we are shipping FAM3A Kits (13) and FAM3A Proteins (5) and many more products for this protein.
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These results suggest that C/EBPbeta (show CEBPB Antibodies) plays an important role in regulating FAM3A promoter activity and FAM3A inhibits adipocyte differentiation.
In the present study, we report a putative human homologue of the antimicrobial Drosophila-derived drosomycin, designated drosomycin-like defensin (show DEF Antibodies) (DLD (show DLD Antibodies)), with specific antifungal activity.
FAM3A plays crucial roles in the regulation of glucose and lipid metabolism in the liver, where it activates the PI3K-Akt signaling pathway by way of a Ca(2+) /CaM-dependent mechanism
Upregulation of FAM3A by PPARgamma (show PPARG Antibodies) activation is correlated with increased pAkt (show AKT1 Antibodies) level in liver cells
FAM3A protects against liver IRI by activating Akt (show AKT1 Antibodies) survival pathways, repressing inflammation and attenuating oxidative stress. Moreover, the protective effects of PPARgamma (show PPARG Antibodies) agonist(s) on liver IRI are dependent on FAM3A-ATP-Akt (show AKT1 Antibodies) pathway.
FAM3A enhances the adipogenesis of preadipocytes by activating ATP-P2 receptor-Akt (show AKT1 Antibodies) pathway. Under obese condition, a decrease in FAM3A expression in adipose tissues plays important roles in the development of adipose dysfunction and type 2 diabetes.
FAM3A has a protective role against cytotoxicity via regulating the CHOP (show DDIT3 Antibodies)-Wnt (show WNT2 Antibodies) pathway in mitochondria.
May act as a defensin against invading fungal microorganisms.
family with sequence similarity 3, member A
, cytokine-like protein 2-19
, protein FAM3A