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Fc Fragment of IgG, Low Affinity IIa, Receptor (CD32) Proteins (FCGR2A)

FCGR2A encodes one member of a family of immunoglobulin Fc receptor genes found on the surface of many immune response cells. Additionally we are shipping Fc Fragment of IgG, Low Affinity IIa, Receptor (CD32) Antibodies (197) and Fc Fragment of IgG, Low Affinity IIa, Receptor (CD32) Kits (19) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
FCGR2A 2212 P12318
FCGR2A    
FCGR2A 450194  
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Top Fc Fragment of IgG, Low Affinity IIa, Receptor (CD32) Proteins at antibodies-online.com

Showing 10 out of 34 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$4,744.22
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 50 to 55 Days
$6,616.87
Details
Human Cells Human His tag 100 μg Log in to see 20 to 21 Days
$382.80
Details
HEK-293 Cells Human Strep Tag,His tag 100 μg Log in to see 2 to 3 Days
$308.00
Details
Baculovirus infected Insect Cells Human His tag 100 μg Log in to see 20 to 21 Days
$382.80
Details
CHO Cells Human His tag 100 μg Log in to see 20 to 21 Days
$382.80
Details
Human Cells Rhesus Monkey His tag 100 μg Log in to see 20 to 21 Days
$437.80
Details
Human Cells Cynomolgus AVI tag,His tag 100 μg Log in to see 20 to 21 Days
$437.80
Details
Mammalian Cells Human His tag   50 μg Log in to see 4 Days
$280.50
Details
Human Cells Cynomolgus His tag 100 μg Log in to see 20 to 21 Days
$437.80
Details

FCGR2A Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , , , , , ,
, , , , , , , ,
Cynomolgus
, ,
Chimpanzee

Top referenced Fc Fragment of IgG, Low Affinity IIa, Receptor (CD32) Proteins

  1. Human FCGR2A Protein expressed in Human Cells - ABIN2002712 : Stuart, Simister, Clarkson, Kacinski, Shapiro, Mellman: Human IgG Fc receptor (hFcRII, CD32) exists as multiple isoforms in macrophages, lymphocytes and IgG-transporting placental epithelium. in The EMBO journal 1990 (PubMed)
    Show all 3 Pubmed References

More Proteins for Fc Fragment of IgG, Low Affinity IIa, Receptor (CD32) (FCGR2A) Interaction Partners

Human Fc Fragment of IgG, Low Affinity IIa, Receptor (CD32) (FCGR2A) interaction partners

  1. When higher-affinity genotypes for FCGR2A, FCGR3A (show CD16 Proteins), and FCGR2C were considered together, they were associated with significantly increased tumor shrinkage and prolonged survival in response to HD-IL2 (show IL2 Proteins)... this is the first study to show associations of FCGR genotypes with outcome following HD-IL2 (show IL2 Proteins) treatment

  2. FcgammaRIIA and FcgammaRIIB both demonstrated increased methylation levels in Kawasaki disease (KD) patients that underwent IVIG treatment. FcgammaRIIA expression influenced the IVIG treatment response of KD patients. The FcgammaRIIA/IIB mRNA expression ratio was greater in KD patients with coronary artery lesion formation.

  3. FCGR2A rs1801274 G-allele confers susceptibility to Kawasaki disease and Ulcerative colitis

  4. farletuzumab has enhanced binding to FCGR3A-158V high-affinity receptor and has an enhanced clinical outcome in ovarian cancer patients with low baseline CA125 levels and at least 1 high-affinity allele of FCGR2A or FCGR3A

  5. inhibition of Abl (show ABL1 Proteins)/Src (show SRC Proteins) with bosutinib reduced FcgammaRIIA-mediated glomerular neutrophil accumulation and renal injury in experimental, crescentic anti-GBM nephritis.

  6. The present study demonstrates that p.His167Arg, a KD-associated FCGR2A variant, acts as a susceptibility gene in males only. Overall, the gender differences associated with FCGR2A in KD provide a new insight into KD susceptibility.

  7. Data indicate a mechanism in which Toll (show TLR4 Proteins)-like receptors TLR7 (show TLR7 Proteins)/8 signaling, through shedding of FcgRIIA, shifts neutrophil function from phagocytosis to a programmed necrosis pathway, neutrophil extracellular trap formation (NETosis).

  8. Gene copy number variation (CNV) of the PKLR (show PKLR Proteins), FCGR2A, FCGR2C, and FCGR3 (show CD16 Proteins) genes is associated with malaria severity, and our results provide evidence for a role of CNV in host responses to malaria.

  9. This study demonstrated that no association between FCGR2A polymorphisms in Guillain-Barre Syndrome in a Brazilian population.

  10. FCGR3A (show CD16 Proteins) V and FCGR2A R allele carriers show better responsiveness to anti-TNF-alpha (show TNF Proteins) therapy--{REVIEW}

Fc Fragment of IgG, Low Affinity IIa, Receptor (CD32) (FCGR2A) Protein Profile

Protein Summary

This gene encodes one member of a family of immunoglobulin Fc receptor genes found on the surface of many immune response cells. The protein encoded by this gene is a cell surface receptor found on phagocytic cells such as macrophages and neutrophils, and is involved in the process of phagocytosis and clearing of immune complexes. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with FCGR2A

  • Fc fragment of IgG receptor IIa (FCGR2A)
  • CD32 protein
  • CD32a protein
  • CDw32 protein
  • FCG2 protein
  • FcGR protein
  • FCGR2 protein
  • FCGR2A1 protein
  • IGFR2 protein

Protein level used designations for FCGR2A

Immunoglobulin G Fc receptor II , fc-gamma RII-a , fc-gamma-RIIa , fcRII-a , igG Fc receptor II-a , low affinity immunoglobulin gamma Fc region receptor II-a , Fc fragment of IgG, low affinity IIa, receptor for (CD32) , Fc gamma receptor IIa

GENE ID SPECIES
2212 Homo sapiens
450194 Pan troglodytes
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