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FLRT2 encodes a member of the fibronectin leucine rich transmembrane protein (FLRT) family.
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OPCML (show OPCML Antibodies) and FLRT2 were further validated in an independent cohort consisting of 20 low-Gleason and 33 high-Gleason tissues. We then compared patients with biochemical recurrence (n=70) vs. those without (n=86) in a third cohort, and they showed no difference in methylation at these DMR (show WDR20 Antibodies) loci
The membrane protein, FLRT2, was identified as a novel autoantigen in systemic lupus erythematosus patients.
PCMC expression of ADAM29 (show ADAM29 Antibodies), FLRT2, and SLC18A3 (show SLC18A3 Antibodies) could be assessed as part of a routine screen to help identify individuals at risk of severe Obstructive sleep apnea in Asian populations
fibronectin leucine-rich transmembrane protein 2 (FLRT2), a repulsive ligand of the UNC5 receptor (show UNC5B Antibodies) family for neurons, is unexpectedly expressed in endothelial cells specifically in the placental labyrinth.
Data show that Unc5 cell guidance receptor Unc5D (show UNC5D Antibodies) controls Latrophilin3 (LPHN3 (show LPHN3 Antibodies))-FLRT protein FLRT2-mediated cell adhesion.
FLRT2 may exist in both membrane-bound and shed forms which interact with fibronectin (show FN1 Antibodies) in the ATDC5 chondroprogenitor cells.
findings provide evidence for a role of FLRT2 in enhancing cell proliferation and reducing intercellular adhesion during the early stages of chondrogenesis
mouse embryos lacking Flrt2 expression arrest at mid-gestation owing to cardiac insufficiency
Flrt2 was highly expressed initially in the cranial neural crest cells
FLRT2 is expressed in a subset of the sclerotome, adjacent to the region that forms the syndetome in embryo
This gene encodes a member of the fibronectin leucine rich transmembrane protein (FLRT) family. FLRT family members may function in cell adhesion and/or receptor signalling. Their protein structures resemble small leucine-rich proteoglycans found in the extracellular matrix.
fibronectin leucine rich transmembrane protein 2
, leucine-rich repeat transmembrane protein FLRT2-like
, fibronectin-like domain-containing leucine-rich transmembrane protein 2
, leucine-rich repeat transmembrane protein FLRT2