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Follistatin-like 3 is a secreted glycoprotein of the follistatin-module-protein family. Additionally we are shipping FSTL3 Antibodies (47) and FSTL3 Kits (31) and many more products for this protein.
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Mouse (Murine) FSTL3 Protein expressed in Human Cells - ABIN2007181
Bartholin, Destaing, Forissier, Martel, Maguer-Satta, Jurdic, Rimokh: FLRG, a new ADAM12-associated protein, modulates osteoclast differentiation. in Biology of the cell / under the auspices of the European Cell Biology Organization 2005
Show all 5 Pubmed References
FSTL3 KO lead to increased activin signaling, enhancing alpha- to beta-cell transdifferentiation in mouse islets.
FSTL3 is a critical mediator of exercise-dependent bone formation
Data indicate that deletion of activin antagonists follistatin-like-3 (FSTL3) results in hepatic steatosis
Suggest FSTL3 has a role in paracrine communication between cardiomyocytes and fibroblasts.
crucial roles for FSTL3 in limiting testis organ size and promoting age-related testicular regression
These findings link FSTL3 and TGFbeta (show TGFB1 Proteins) ligand signaling and a novel subset of the synexpression group of genes to organ/tissue-specific regulatory pathways.
These results demonstrate that body composition and glucose homeostasis are differentially regulated by FST (show FST Proteins) and FSTL3 and that their combined loss is associated with increased fat mass and insulin (show INS Proteins) resistance despite elevated insulin (show INS Proteins) production.
Fstl3 as a stress-induced regulator of hypertrophy that controls myocyte size via regulation of Smad (show SMAD1 Proteins) signaling.
regulation and expression patterns of follistatin (show FST Proteins) and FLRG differ; FLRG is distributed in spermatogenic cells of the testis, renal tubules, epithelial cells of the lung, and myocardium
review with emphasis on authors' works on paracrine and autocrine regulation in activities of Fst (show FST Proteins) and Fstl3, regulation of gonadal development, and structural elements necessary for biological activities
Elevated FSTL-3 concentrations were attributable to preeclampsia and were associated with increased likelihood of later developing preeclampsia, suggesting further study as a biomarker prior to clinically evident disease.
The elevation of Follistatin-like-3 was demonstrated in late second trimester of pregnancy destined to developing preeclampsia, suggesting its causal role in the pathogenesis and prediction of preeclampsia.
Resistance exercise resulted in a significant downregulation of MSTN (show MSTN Proteins) and FBXO32 (show FBXO32 Proteins) mRNA expression and a significant upregulation in FSTL3 and SMURF1 (show SMURF1 Proteins) mRNA expression, and carbohydrate and protein feeding have little influence on the these markers expression.
Data suggest that serum levels of FSTL3 are higher in pre-eclampsia than in controls; placental expression of FSTL3 is also increased in pre-eclampsia compared with controls; no differences were observed between mild and severe pre-eclampsia.
After eccentric exercise, postmenopausal women not using hormone therapy (HT) expressed higher levels of follistatin-like protein 3 while postmenopausal women using HT showed a significant increased expression over controls.
Maternal and placental FSTL3 concentrations were reduced in GDM women compared with normally pregnant women, suggesting FSTL3 may play an important role in the pathogenesis of gestational diabetes
Structure of myostatin.follistatin-like 3: N-terminal domains of follistatin (show FST Proteins)-type molecules exhibit alternate modes of binding.
GDF9 (show GDF9 Proteins) decreases basal and activin A (show INHBA Proteins)-induced FST (show FST Proteins) and FSTL3 expression, and this explains, in part, its enhancing effects on activin A (show INHBA Proteins)-induced inhibin beta(B)-subunit (show INHBB Proteins) mRNA expression and inhibin B production in hGL (show LLGL2 Proteins) cells
Follistatin-like 3 is a secreted glycoprotein of the follistatin-module-protein family. It may have a role in leukemogenesis.
follistatin-like protein 3
, follistatin-related gene protein
, follistatin-related protein 3