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FOXF2 encodes forkhead box F2, one of many human homologues of the Drosophila melanogaster transcription factor forkhead. Additionally we are shipping FOXF2 Antibodies (46) and many more products for this protein.
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Data show that expression pattern of XFoxF2 during embryonic development, metamorphosis and adulthood.
FOXF2 rs1711972 AA genotype is associated with poor response to therapy in Non-small Cell Lung Cancer.
miR130a can regulate FOXF2 and function as an oncogene (show RAB1A Proteins) in colorectal cancer.
FOXF2 deficiency induced mesenchymal-epithelial transition (MET) in Huh7 cell which might facilitate the colonization of circulating tumor cells and the formation of metastasis.
Cox (show COX8A Proteins) proportional hazards regression model was used to evaluate the predictive value of FOXF2 mRNA level in non-small cell lung cancer patients
FOXF2 has a dual role in breast tumorigenesis and functions as either a tumor suppressor or an oncogene (show RAB1A Proteins) depending on the breast tumor subtype.
MAZ (show MAZ Proteins)/FOXF2 axis can promote the proliferation of basal like breast cancer cells and suppress disease progression.
direct targeting of Foxf2 by Shh (show SHH Proteins) signaling drives cranial neural crest cell mesenchyme proliferation during upper lip morphogenesis, and disruption of this sequence results in cleft lip.
Common variants near FOXF2 that are associated with increased stroke susceptibility.
No correlation was found between FOXF2 promoter methylation and other clinic pathological parameters (age, gender, differentiation, lymph node metastasis, stage, cutting edge, vascular invasion, smoking behavior, and drinking history) in esophageal squamous cell carcinoma.
Loss of FOXF2 Expression is associated with Hepatocellular Carcinoma.
Foxf2(-/-) maxillary explants cultured in vitro, in the absence of tongue and mandible, failed to close the secondary palate. Proliferation and collagen content were decreased in Foxf2(-/-) palatal shelf mesenchyme. Phosphorylation of Smad2 (show SMAD2 Proteins)/3 was reduced in mutant palatal shelf, diagnostic of attenuated canonical Tgfbeta (show TGFB1 Proteins) signaling, whereas phosphorylation of p38 (show CRK Proteins) was increased.
novel Shh (show SHH Proteins)-Foxf (show FOXF1 Proteins)-Fgf18 (show FGF18 Proteins)-Shh (show SHH Proteins) circuit in the palate development molecular network, in which Foxf1 (show FOXF1 Proteins) and Foxf2 regulate palatal shelf growth downstream of Shh (show SHH Proteins) signaling, at least in part, by repressing Fgf18 (show FGF18 Proteins) expression
Foxf2 inactivation in adults resulted in blood-brain barrier breakdown, endothelial thickening, and increased trans-endothelial vesicular transport
Our findings implicate Foxf (show FOXF1 Proteins) genes(Foxf1a (show FOXF1 Proteins) and Foxf2 ) in atrioventricular septation, describe the molecular underpinnings of the genetic interaction between Hedgehog (show SHH Proteins) signaling and Tbx5 (show TBX5 Proteins)
results indicate that Foxf2 signaling in smooth muscle cells is essential for intestinal development and serum response factor signaling
Foxf2 is a fibroblast factor that inhibits paracrine Wnt (show WNT2 Proteins) signaling and restricts the crypt stem cell niche in intestines of mice. Loss of Foxf2 promotes adenoma formation and growth.
These data provide evidence that the Foxf2 gene, separated from Foxc1 (show FOXC1 Proteins) by less than 70 kb of genomic sequence (250 kb in human DNA), may explain human abnormalities in some cases of ASD (show GUSB Proteins) where FOXC1 (show FOXC1 Proteins) has been excluded genetically.
findings argue that Foxf2 is a previously unrecognized regulator of cellular and systemic whole body glucose tolerance, at least in part, due to lower levels of IRS1 (show IRS1 Proteins).
Foxf2 gene plays key roles in palatogenesis by reshaping the growing tongue.
FOXF2 encodes forkhead box F2, one of many human homologues of the Drosophila melanogaster transcription factor forkhead. FOXF2 is expressed in lung and placenta, and has been shown to transcriptionally activate several lung-specific genes.
forkhead box F2
, forkhead box protein F2
, forkhead-like 6
, forkhead-related activator 2
, forkhead-related protein FKHL6
, forkhead-related transcription factor 2
, forkhead homolog 20