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displays fucosyltransferase activity for type 2 (Gal beta1-->GlcNac)-containing oligosaccharides and neolactotetraosylceramide [RGD, Feb 2006]..
Showing 6 out of 10 products:
This study suggests that baicalin facilitates endometrial reproduction via elevating FUT4 expression through Wnt (show WNT2 Proteins)/beta-catenin (show CTNNB1 Proteins) signaling pathway
We found that Fut1 (show FUT1 Proteins) mRNA and Fut4 mRNA were upregulated, while Fut2 (show FUT2 Proteins) mRNA and Fut9 (show FUT9 Proteins) mRNA were downregulated by androgen in the caput epididymis.
Demonstration for the first time that CD15 is expressed in non-neural stem-like cancer cells.
alpha(1,3)-Fucosyltransferases FUT4 and FUT7 (show FUT7 Proteins) control murine susceptibility to thrombosis
Functional PSGL-1 generated by basophil FT-IV/VII and its subsequent binding to L-selectin could be one of the essential steps required for initial basophil recruitment and the development of IgE-chronic allergic inflammation in mice.
LRP1 (show LRP1 Proteins) is necessary for the differentiation of neural stem cells toward oligodendrocytes. However, this function is independent of LeX glycosylation.
Findings suggest that Lewis X carbohydrates, which have so far been characterized as undifferentiation markers, actually operate as activators of the Notch (show NOTCH1 Proteins) signaling pathway for the maintenance of NSC stemness during brain development.
MiR-34a targeting of Notch ligand delta-like 1 impairs CD15+/CD133+ tumor-propagating cells and supports neural differentiation in medulloblastoma
undifferentiated embryonal cells were evident histologically and confirmed with two markers of pluripotency, namely OCT4 (show POU5F1 Proteins) and SSEA-1 and these cells are highly mitotic
Fucosyltransferase(Fut)-deficient (Fut1 (show FUT1 Proteins), Fut2 (show FUT2 Proteins) and Fut4) mice which lack LeX or LeY antigen are still fertile.
The identified colorectal cancer-restricted miR-26a and miR-26b might be implicated in cancer progression via their target gene FUT4.
CD15 is a significant prognostic factor in clear cell renal cell carcinoma (show MOK Proteins).
FUT4/LeY was critical to the TAMs-mediated EMT; this process might be associated with the up-regulation of Ezrin phosphorylation by FUT4/LeY-mediated fucosylation
study enhances the understanding of cancer cell-brain endothelial adhesion and confirms that CD15 plays a crucial role in adhesion
We observed an upregulation of the transcription factors OCT4 and SOX2 in leukemic cells as compared to normal cells. Conversely, SSEA1 protein was downregulated in leukemic cells. The expression of OCT4, SOX2, and SSEA3 was higher in CD34(+)CD38(-) than in CD34(+)CD38(+) subsets in leukemic cells.
The miR-493-5p/FUT4 pathway has therapeutic potential in breast cancer.
expression of SSEA-1 immunoreactivity in thyroid neoplasms was associated with more aggressive thyroid carcinomas
Data show that after FUT4 down-regulated with siRNA (shFUT4), epithelial-mesenchymal transition (EMT (show ITK Proteins)) was obviously inhibited.
Ginsenoside Rg3 induces FUT4-mediated apoptosis in H. pylori CagA (show S100A8 Proteins)-treated gastric cancer cells by regulating SP1 (show PSG1 Proteins) and HSF1 (show HSF1 Proteins) expressions
the acquisition of a sialyl moiety by the CD15 antigen may precede the widespread dissemination in Hodgkin lymphoma.
displays fucosyltransferase activity for type 2 (Gal beta1-->GlcNac)-containing oligosaccharides and neolactotetraosylceramide
, Lewis x
, alpha (1,3) fucosyltransferase, myeloid specific
, alpha 1,3-fucosyltransferase
, fucosyltransferase IV
, galactoside 3-L-fucosyltransferase
, stage-specific embryonic antigen 1
, ELAM ligand fucosyltransferase
, ELAM-1 ligand fucosyltransferase
, Lewis X
, alpha 1,3-fucosyltransferase Fuc-T (similar to mouse Fut4)
, alpha 13-fucosyltransferase Fuc-T (similar to mouse Fut4)