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The protein encoded by FUT6 is a Golgi stack membrane protein that is involved in the creation of sialyl-Lewis X, an E-selectin ligand. Additionally we are shipping Fucosyltransferase 6 (Alpha (1,3) Fucosyltransferase) Kits (10) and Fucosyltransferase 6 (Alpha (1,3) Fucosyltransferase) Proteins (4) and many more products for this protein.
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characterisation of FUT4 and FUT6 alpha-(1 --> 2)-fucosyltransferases
FUT6 contributed to fucosylation of root arabinogalactan-proteins.
AtFUT4 and AtFUT6 are the first enzymes to be characterized for AGP glycosylation
data suggest that both FUT5 (show FUT5 Antibodies) and FUT6 can promote the development of colorectal cancer (CRC (show CALR Antibodies)) via the PI3K (show PIK3CA Antibodies)/Akt (show AKT1 Antibodies) signalling pathway, which is regulated by miR (show MLXIP Antibodies)-125a-3p. miR (show MLXIP Antibodies)-125a-3p may serve as a predictive biomarker and a potential therapeutic target in CRC (show CALR Antibodies) treatment.
meta-analysis identified new variants, rs3760775 (P = 1.2 x 10-23) and rs78060698 (P = 8.3 x 10-17) in FUT6 to be associated with circulating B12 (show NDUFB3 Antibodies) concentrations.
ur results strongly showed that the low expression of FUT6 regulated by miR (show MLXIP Antibodies)-106b contributed to cell migration, invasion, and proliferation in human breast cancer.
There were significant differences between the type 2 diabetes mellitus patients and controls in the risk allele distributions of rs3792267 (CAPN10 (show CAPN10 Antibodies)) (P = 0.002), rs1501299 (APM1 (show ZBTB7C Antibodies)) (P = 0.017), and rs3760776 (FUT6) (P = 0.031).
The T allele of rs3760776 might repress the transcription of the FUT6 gene.
In normal colon samples a significant relationship between sLe(x) expression and the ratio between FUT6/B4GALNT2 (show B4GALNT2 Antibodies) activities exists, demonstrating for the first time a role for B4GALNT2 (show B4GALNT2 Antibodies) in sLe(x) inhibition in vivo
Results suggest that FUT4 (show FUT4 Antibodies)-, FUT6- or FUT8 (show FUT8 Antibodies)-mediated MDR in human HCC (show FAM126A Antibodies) is associated with the activation of the PI3K (show PIK3CA Antibodies)/Akt (show AKT1 Antibodies) pathway and the expression of MRP1 (show MDM4 Antibodies).
these results suggest that FUT6 plays an important role in hepatocellular carcinoma growth by regulating the PI3K (show PIK3CA Antibodies)/Akt (show AKT1 Antibodies) signaling pathway.
The biosynthesis of the selectin-ligand sialyl Lewis x (show FUT4 Antibodies) in colorectal cancer tissues is regulated by fucosyltransferase VI and can be inhibited by an RNA interference-based approach.
GALNT14 (show GALNT14 Antibodies) and FUT3 (show FUT3 Antibodies)/6 H-scores were significantly higher in non-small cell lung cancer cell lines sensitive to dulanermin and drozitumab versus resistant cell lines
The protein encoded by this gene is a Golgi stack membrane protein that is involved in the creation of sialyl-Lewis X, an E-selectin ligand. Mutations in this gene are a cause of fucosyltransferase-6 deficiency. Two transcript variants encoding the same protein have been found for this gene.
, fucosyltransferase 5
, fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
, fucosyltransferase VI
, galactoside 3-L-fucosyltransferase