anti-Fyn-Related Kinase (FRK) Antibodies

The protein encoded by FRK belongs to the TYR family of protein kinases. Additionally we are shipping FRK Proteins (12) and FRK Kits (8) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
FRK 2444 P42685
FRK 14302 Q922K9
FRK 79209 Q62662
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Top anti-FRK Antibodies at antibodies-online.com

Showing 10 out of 176 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB <b>WB Suggested Anti-FRK Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>Transfected 293T 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB <b>WB Suggested Anti-FRK Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>721_B cell lysate WB Suggested Anti-FRK <br /> Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500 <br /> Positive Control:.21_B cell lysate <br /> FRK is supported by BioGPS gene expression data to be expressed in 721_B 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated FACS, IF, IHC, IHC (p), WB 100 μL Log in to see 7 to 9 Days
$507.83
Details
Human Rabbit Un-conjugated IC, IF, IHC, WB Immunofluorescent analysis of FRK staining in K562 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Immunohistochemical analysis of FRK staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Human Mouse Un-conjugated FACS, IF 100 μL Log in to see 7 to 9 Days
$507.83
Details
Human Rabbit Un-conjugated IF, IHC, ELISA, WB Western blot analysis of extracts from Jurkat cells, using FRK Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using FRK Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated WB WB Image Sample(30 μg of whole cell lysate) A:MOLT4, 7.5% SDS PAGE antibody diluted at 1:500 100 μL Log in to see 1 to 2 Days
$358.60
Details
Human Mouse Un-conjugated ELISA, IHC, WB Figure 1: Western blot analysis using FRK mouse mAb against HEK293T cells transfected with the pCMV6-ENTRY control (1) and pCMV6-ENTRY FRK cDNA (2). Dilution: 1/500 - 1/2000 Figure 2: Western blot analysis using FRK mouse mAb against truncated FRK-His recombinant protein (1). Dilution: 1/500 - 1/2000 100 μL Log in to see 10 to 11 Days
$439.57
Details
Human Mouse Un-conjugated ELISA, IHC, IHC (p), WB Human Breast: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μL Log in to see 7 to 9 Days
$484.00
Details
Dog Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details

FRK Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-FRK Antibodies

  1. Human Monoclonal FRK Primary Antibody for IHC, ELISA - ABIN969157 : Strausberg, Feingold, Grouse, Derge, Klausner, Collins, Wagner, Shenmen, Schuler, Altschul, Zeeberg, Buetow, Schaefer, Bhat, Hopkins, Jordan, Moore, Max, Wang, Hsieh, Diatchenko, Marusina, Farmer et al.: Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. ... in Proceedings of the National Academy of Sciences of the United States of America 2002 (PubMed)
    Show all 2 Pubmed References

  2. Cow (Bovine) Polyclonal FRK Primary Antibody for WB - ABIN2774079 : Zhang, Gong, Wang, Wang, Ran: [Deoxycholate induces apoptosis in cultured normal human esophageal mucosal epithelial cells]. in Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA 2005 (PubMed)
    Show all 2 Pubmed References

  3. Cow (Bovine) Polyclonal FRK Primary Antibody for WB - ABIN2785801 : Zhang, Wolf-Yadlin, Ross, Pappin, Rush, Lauffenburger, White: Time-resolved mass spectrometry of tyrosine phosphorylation sites in the epidermal growth factor receptor signaling network reveals dynamic modules. in Molecular & cellular proteomics : MCP 2005 (PubMed)
    Show all 2 Pubmed References

More Antibodies against FRK Interaction Partners

Human Fyn-Related Kinase (FRK) interaction partners

  1. our results present the first evidence that site-specific promoter methylation contributes to the repression of FRK more so in basal B breast cancers.

  2. Loss of FRK protein may be implicated into the tumorigenesis and cell motility/invasiveness of human cervical cancer.

  3. antagomir-1290 significantly inhibited the proliferation, clonogenicity, invasion, and migration of CD133(+) cells by targeting fyn (show FYN Antibodies)-related Src (show SRC Antibodies) family tyrosine kinase (show TXK Antibodies).

  4. our results demonstrate a combined mechanism for the anti-proliferative effects of FRK by inhibiting cyclin D1 (show CCND1 Antibodies) nucleus accumulation and pRb (show RB1 Antibodies) phosphorylation in glioma cells.

  5. FRK over-expression promoted beta-catenin (show CTNNB1 Antibodies) translocation to the plasma membrane, where it formed complex with N-cadherin (show CDH2 Antibodies).

  6. exome sequencing identified recurrent somatic FRK mutations that induce constitutive kinase activity, STAT3 (show STAT3 Antibodies) activation, and cell proliferation sensitive to Src (show SRC Antibodies) inhibitors

  7. Data indicaate that the Rak/Frk SH2 and SH3 domains collaborate to increase the Rak-EGFR (show EGFR Antibodies) interaction.

  8. The expression levels of FRK were significantly correlated with invasiveness in both Hep3B and HepG2 tumor cell lines.

  9. these results clearly indicate that FRK may play a protective role against the progression of glioma by suppressing cell migration and invasion

  10. Genetic variation near FRK/COL10A1 (show COL10A1 Antibodies) and VEGFA (show VEGFA Antibodies) are associated with advanced age-related macular degeneration.

Mouse (Murine) Fyn-Related Kinase (FRK) interaction partners

  1. Characterization of mice deficient in the Src (show SRC Antibodies) family nonreceptor tyrosine kinase (show TYRO3 Antibodies) Frk/rak. Decreases in the circulating levels of T3 but not T4 are reminiscent of euthyroid sick syndrome, a stress-associated clinical condition

  2. The tyrosine kinases Brk/PTK6/Sik (show PTK6 Antibodies), Srm (show SRM Antibodies), Frk/Rak/Gtk/Iyk/Bsk (show EPHA5 Antibodies), and Src42A/Dsrc41 have a low degree of sequence homology to other known kinases. The exon structure of these kinases, called the Brk (show PTK6 Antibodies) family, is highly conserved and distinct.

  3. Experiments with Fyn (show FYN Antibodies)-deficient mice indicate that Fyn (show FYN Antibodies) genotype does not influence ethanol consumption, neither under basal conditions nor following a deprivation period or stress.

  4. These results show that FRK affects beta cell number during embryogenesis and early in life, but is probably redundant for beta cell number and function in adult animals under normal conditions.

FRK Antigen Profile

Protein Summary

The protein encoded by this gene belongs to the TYR family of protein kinases. This tyrosine kinase is a nuclear protein and may function during G1 and S phase of the cell cycle and suppress growth.

Gene names and symbols associated with FRK

  • fyn related Src family tyrosine kinase (FRK) antibody
  • Fyn-related kinase (FRK) antibody
  • fyn-related kinase (Frk) antibody
  • fyn-related Src family tyrosine kinase (Frk) antibody
  • fyn related Src family tyrosine kinase (frk) antibody
  • tyrosine-protein kinase FRK (LOC100540680) antibody
  • fyn related Src family tyrosine kinase (Frk) antibody
  • BSK antibody
  • BSK/IYK antibody
  • C85044 antibody
  • FRK antibody
  • GTK antibody
  • PTK5 antibody
  • RAK antibody

Protein level used designations for FRK

PTK5 protein tyrosine kinase 5 , nuclear tyrosine protein kinase RAK , protein-tyrosine kinase 5 , tyrosine-protein kinase FRK , hypothetical protein LOC583550 , fyn-related kinase , B-cell src-homology tyrosine kinase , beta-cell Src-homology tyrosine kinase , intestine tyrosine kinase , GASK , GTK , gastrointestinal-associated kinase , gastrointestinal-associated tyrosine kinase , src related tyrosine kinase , tyrosine-protein kinase FRK-like

GENE ID SPECIES
2444 Homo sapiens
583550 Strongylocentrotus purpuratus
481970 Canis lupus familiaris
462953 Pan troglodytes
716267 Macaca mulatta
14302 Mus musculus
421747 Gallus gallus
79209 Rattus norvegicus
509227 Bos taurus
100403046 Callithrix jacchus
100448548 Pongo abelii
100488362 Xenopus (Silurana) tropicalis
100540680 Meleagris gallopavo
100593495 Nomascus leucogenys
100726734 Cavia porcellus
100157810 Sus scrofa
Selected quality suppliers for anti-FRK (FRK) Antibodies
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