anti-G Protein-Coupled Receptor, Family C, Group 5, Member A (GPRC5A) Antibodies

GPRC5A encodes a member of the type 3 G protein-coupling receptor family, characterized by the signature 7-transmembrane domain motif. Additionally we are shipping GPRC5A Kits (19) and GPRC5A Proteins (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
GPRC5A 9052 Q8NFJ5
GPRC5A 232431  
GPRC5A 312790  
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Top anti-GPRC5A Antibodies at antibodies-online.com

Showing 10 out of 113 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-GPCR5A Antibody Titration:  0.2-1 ug/ml  Positive Control:  Jurkat cell lysate Host:  Rabbit  Target Name:  GPCR5A  Sample Type:  Jurkat  Lane A:  Primary Antibody  Lane B:  Primary Antibody + Blocking Peptide  Primary Antibody Concentration:  1ug/ml  Peptide Concentration:  5ug/ml  Lysate Quantity:  25ug/lane/lane  Gel Concentration:  0.12 100 μL 2 to 3 Days
$319.00
Details
Human Rabbit Un-conjugated ICC, IHC, IHC (p) Anti-GPRC5A / RAI3 antibody IHC staining of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN1048905 dilution 18-36 ug/ml. Anti-GPRC5A / RAI3 antibody IHC staining of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN1048905 dilution 18-36 ug/ml. 50 μg 11 to 14 Days
$484.00
Details
Human Rabbit Un-conjugated IHC, IHC (p) Human, Uterus: Formalin-Fixed Paraffin-Embedded (FFPE) Human, Prostate: Formalin-Fixed Paraffin-Embedded (FFPE) 50 μg 11 to 14 Days
$484.00
Details
Human Rabbit Un-conjugated ICC, IHC, IHC (p) Anti-GPRC5A / RAI3 antibody IHC staining of human brain, neurons. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN1048907 dilution 41551 ug/ml. Anti-GPRC5A / RAI3 antibody IHC staining of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN1048907 dilution 41551 ug/ml. 50 μg 11 to 14 Days
$484.00
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from K562/LOVO cells, using GPRC5A Antibody. The lane on the right is treated with the synthesized peptide. 100 μg 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated WB   200 μL 13 to 14 Days
$487.50
Details
Human Rabbit Un-conjugated EIA, WB 0.4 mL 6 to 8 Days
$484.00
Details
Human Rabbit Un-conjugated IHC, IHC (p) Anti-GPRC5A / RAI3 antibody  ABIN1048909 IHC staining of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Anti-GPRC5A / RAI3 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg 11 to 14 Days
$484.00
Details
Human Rabbit Un-conjugated ICC, IHC, IHC (p) Anti-GPRC5A / RAI3 antibody  ABIN1048908 IHC staining of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Anti-GPRC5A / RAI3 antibody immunocytochemistry (ICC) staining of HEK293 human embryonic kidney cells transfected with GPRC5A / RAI3. 50 μg 11 to 14 Days
$484.00
Details
Cow Rabbit Un-conjugated WB 100 μL 11 to 14 Days
$581.17
Details

Top referenced anti-GPRC5A Antibodies

  1. Human Polyclonal GPRC5A Primary Antibody for ICC, IF - ABIN4315891 : Jahny, Yang, Liu, Jahnke, Lademann, Knösel, Rümmele, Grützmann, Aust, Pilarsky, Denz: The G Protein-Coupled Receptor RAI3 Is an Independent Prognostic Factor for Pancreatic Cancer Survival and Regulates Proliferation via STAT3 Phosphorylation. in PLoS ONE 2017 (PubMed)
    Show all 2 Pubmed References

  2. Human Polyclonal GPRC5A Primary Antibody for ELISA, WB - ABIN545747 : Cafferata, Gonzalez-Guerrico, Pivetta, Santa-Coloma: Identification by differential display of a mRNA specifically induced by 12-O-tetradecanoylphorbol-13-acetate (TPA) in T84 human colon carcinoma cells. in Cellular and molecular biology (Noisy-le-Grand, France) 1997 (PubMed)
    Show all 3 Pubmed References

More Antibodies against GPRC5A Interaction Partners

Human G Protein-Coupled Receptor, Family C, Group 5, Member A (GPRC5A) interaction partners

  1. On the basis of our findings in human DN and in Gprc5a deficient mice, we believe that chronic reduction in Gprc5a expression plays a pathogenic role in the progression of DN. Results in cell culture support our other findings in mice showing that Gprc5a modulates EGFR and TGF-b signaling in podocytes.

  2. The lung tumor suppressor gene GPRC5A played a protective role in cigarette smoke-induced lung tumor initiation.

  3. RAI3 overexpression is associated with poor prognosis in esophageal cancers

  4. GPRC5a was upregulated in pancreatic cancer (PaCa) leading to an enhanced drug resistance in PaCa cells.

  5. under-expressed GPRC5A during lung tumorigenesis enhances any transcriptional stimulation through an active translational status.

  6. findings reveal an unprecedented role for GPRC5A in regulation of the ITGB1-mediated cell adhesion and it's downstream signaling, thus indicating a potential novel role for GPRC5A in human epithelial cancers.

  7. miR-204 inhibits cell proliferation in gastric cancer by targeting CKS1B, CXCL1 and GPRC5A.

  8. p53 overexpression and GPRC5A induction markedly inhibited tumor cell viability and induced apoptosis.

  9. Mutations of ARID1A, GPRC5A and MLL2 grant bladder cancer non-stem cells the capability of self-renewal.

  10. GPRC5A is a potential oncogene in pancreatic ductal adenocarcinoma cells that is upregulated by gemcitabine with help from HuR.

  11. These results suggest RAI3 plays an important role in adipogenesis of hASCs and may have a potential use in the future application.

  12. Study underscores genomic alterations that represent early events in the development of Kras mutant LUAD following Gprc5a loss and tobacco carcinogen exposure.

  13. Data show that G protein-coupled receptor, family C, group 5, member A protein (GPRC5A) regulates oxidative stress through vanin 1 protein (VNN1).

  14. Suppression of GPRC5a results in decreased cell growth, proliferation and migration in pancreatic cancer cell lines via a STAT3 modulated pathway, independent from ERK activation

  15. our results implicate GPRC5A as a tumor suppressor in breast cancer cells, and GPRC5A exerts its tumor-suppressive function by inhibiting EGFR and its downstream pathway

  16. elevated levels of GPRC5A played significant roles in gastric cancer progression

  17. Results show how GPRC5A deficiency leads to dysregulated EGFR and STAT3 signaling and lung tumorigenesis.

  18. EGFR interacted with GPRC5A and phosphorylated it in two conserved double-tyrosine motifs, Y317/Y320 and Y347/ Y350, at the C-terminal tail of GPRC5A.

  19. The interaction of miR-103a-3p with each of the two 5' UTR targets reduces the expression levels of both GPRC5A mRNA and GPRC5A protein in one normal epithelial and two pancreatic cancer cell lines.

  20. RAI3 may contribute to the malignant progression of hepatocellular carcinoma

Mouse (Murine) G Protein-Coupled Receptor, Family C, Group 5, Member A (GPRC5A) interaction partners

  1. On the basis of our findings in human DN and in Gprc5a deficient mice, we believe that chronic reduction in Gprc5a expression plays a pathogenic role in the progression of DN. Results in cell culture support our other findings in mice showing that Gprc5a modulates EGFR and TGF-b signaling in podocytes.

  2. G protein-coupled receptor family C group 5 member A (GPRC5A) deficiency contributes to dysregulated proto-oncogene protein c-mdm2 (MDM2) via activated epidermal growth factor receptor (EGFR) signaling, which promotes lung tumor development.

  3. GPRC5a was upregulated in pancreatic cancer (PaCa) leading to an enhanced drug resistance in PaCa cells.

  4. under-expressed GPRC5A during lung tumorigenesis enhances any transcriptional stimulation through an active translational status.

  5. Study underscores genomic alterations that represent early events in the development of Kras mutant LUAD following Gprc5a loss and tobacco carcinogen exposure.

  6. Data show that G protein-coupled receptor, family C, group 5, member A protein (Gprc5a) deficiency exacerbates the silica-induced tissue damages and fibrogenic response in lungs.

  7. Gprc5a deficiency leads to impaired induction of peripherally derived regulatory T-cells and increased experimental autoimmune encephalomyelitis severity.

  8. Gprc5a deficiency confers susceptibility to endotoxin-induced pulmonary edema and injury, mainly through NF-kappaB signaling in bronchioalveolar epithelium of lung.

  9. Results show how GPRC5A deficiency leads to dysregulated EGFR and STAT3 signaling and lung tumorigenesis.

  10. Gprc5a deletion enhances the transformed phenotype in normal and malignant lung epithelial cells by eliciting persistent Stat3 signaling induced by autocrine leukemia inhibitory factor.

  11. Loss of GPRC5A is associated with lung adenocarcinomas.

  12. Gprc5a loss enhances NF-kappaB activation in lung epithelial cells

  13. analysis of the Rai3 gene promoter revealed that the proximal region harbors most of the elements necessary for its regulation, including GC boxes and Sp1-, AP1-, and AP2-binding sites, and a retinoic acid response element

  14. Data show that targeted inactivation of Raig1 did not cause significant developmental defects, and tha epithelial cell differentiation was normal and lung structure was intact.

GPRC5A Antigen Profile

Protein Summary

This gene encodes a member of the type 3 G protein-coupling receptor family, characterized by the signature 7-transmembrane domain motif. The encoded protein may be involved in interaction between retinoid acid and G protein signalling pathways. Retinoic acid plays a critical role in development, cellular growth, and differentiation. This gene may play a role in embryonic development and epithelial cell differentiation.

Gene names and symbols associated with GPRC5A

  • G protein-coupled receptor class C group 5 member A (GPRC5A) antibody
  • G protein-coupled receptor, family C, group 5, member A (Gprc5a) antibody
  • G protein-coupled receptor, class C, group 5, member A (Gprc5a) antibody
  • G protein-coupled receptor class C group 5 member A (Gprc5a) antibody
  • GPCR5A antibody
  • Rai3 antibody
  • Raig1 antibody

Protein level used designations for GPRC5A

G-protein coupled receptor family C group 5 member A , RAIG-1 , orphan G-protein-coupling receptor PEIG-1 , retinoic acid induced 3 , retinoic acid responsive , retinoic acid-induced gene 1 protein , retinoic acid-induced protein 3

GENE ID SPECIES
9052 Homo sapiens
232431 Mus musculus
312790 Rattus norvegicus
516026 Bos taurus
486680 Canis lupus familiaris
417960 Gallus gallus
100730088 Cavia porcellus
101110748 Ovis aries
100349493 Oryctolagus cuniculus
100624186 Sus scrofa
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