anti-G Protein-Coupled Receptor 55 (GPR55) Antibodies

Members of the G protein-coupled receptor (GPR) family, such as GPR55, play important roles in signal transduction from the external environment to the inside of the cell (Sawzdargo et al., 1999 [PubMed 9931487]).[supplied by OMIM, Apr 2008].. Additionally we are shipping GPR55 Proteins (3) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
GPR55 9290 Q9Y2T6
GPR55 227326 Q3UJF0
GPR55 501177  
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Top anti-GPR55 Antibodies at antibodies-online.com

Showing 10 out of 57 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Human Rabbit Un-conjugated ELISA, IHC, IHC (p) Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE) Anti-GPR55 antibody IHC staining of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μL 11 to 14 Days
$484.00
Details
Human Rabbit Un-conjugated IHC, IHC (p) Anti-GPR55 antibody  ABIN1048839 IHC staining of human brain, putamen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg 11 to 14 Days
$484.00
Details
Human Rabbit Un-conjugated IHC, IHC (p) Anti-GPR55 antibody  ABIN1048837 IHC staining of human pancreas, islet of Langerhans. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Anti-GPR55 antibody IHC of human pancreas, islet of Langerhans. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg 11 to 14 Days
$484.00
Details
Human Rabbit Un-conjugated IHC, IHC (p) Anti-GPR55 antibody  ABIN1048838 IHC staining of human brain, putamen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Anti-GPR55 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg 11 to 14 Days
$484.00
Details
Human Rabbit Un-conjugated ELISA, ICC, IF, IHC (p), WB Immunohistochemical staining of paraffin embedded pig kidney tissue using anti-GPR55 (primary antibody at 1: 100) IHC-P staining of pig kidney tissue using anti-GPR55 (dilution at 1: 100) 100 μg 10 to 15 Days
$521.89
Details
Human Rabbit Un-conjugated IHC (p) IHC-P Image GPR55 antibody [C2C3], C-term detects GPR55 protein at membrane on human prostate by immunohistochemical analysis. Sample: Paraffin-embedded prostate. GPR55 antibody [C2C3], C-term , dilution: 1:100. 100 μL 3 to 4 Days
$466.18
Details
Human Rabbit Alexa Fluor 488 IF (p) RSC96 cells probed with GPR55 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated (bs-7686R-A488) at 1:2 for 30 minutes compared to control cells (blue) and isotype control (orange). 100 μL 14 to 21 Days
$416.90
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat brain labeled with Anti GPR55 Polyclonal Antibody, Unconjugated (ABIN872750) at 1:200 followed by conjugation to the secondary antibody and DAB staining. Lane 1: mouse brain lysates Lane 2: mouse embryo lysates probed with Anti GPR55 Polyclonal Antibody, Unconjugated  at 1:200 in 4˚C. Followed by conjugation to secondary antibody -HRP) at 1:3000 90min in 37˚C. Predicted band 37kD. Observed band size: 37kD. 100 μL 3 to 7 Days
$317.90
Details
Human Rabbit Un-conjugated ELISA, IHC, WB Western blot analysis of GPR55 expression in HEK293 cells ,The lane on the left is treated with the antigen-specific peptide. ABIN6273882 at 1/100 staining Human liver cancer tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary. 100 μL 11 to 12 Days
$390.77
Details
Human Rabbit Un-conjugated ELISA, WB   100 μL 11 to 13 Days
$335.04
Details

More Antibodies against GPR55 Interaction Partners

Human G Protein-Coupled Receptor 55 (GPR55) interaction partners

  1. Our findings support the hypothesis that neural stem cells (NSC) express functional GPR55 and that targeting GPR55 with selective agonists increases NSC proliferation and early neurogenesis both in vitro and in vivo. A better understanding of the role GPR55 plays during neurogenesis may provide new prospects for therapeutic treatments utilizing this receptor as a target.

  2. The GPR55 gene expressions were significantly lower in the Dorsolateral Prefrontal Cortex of suicide cases.

  3. GPR55 is involved in the migratory behavior of human breast cancer cells.

  4. Inhibition of GPR55 activity produces antitumor effects via attenuation of the MEK/ERK and PI3K-AKT pathways leading to a reduction in the expression and function of MDR proteins.

  5. our data suggest that GPR55 and CB1 play differential roles in colon carcinogenesis where the former seems to act as oncogene and the latter as tumor suppressor.

  6. GPR55 was highly expressed by beta-cells of both humans and mice. It was also present in a small proportion of mouse islet alpha-cells and in the majority of human islet alpha-cells, but it was absent or at very low levels in delta-cells of both species. GPR55 was preferentially expressed in the endocrine pancreas, with only faint immunoreactivity in the exocrine pancreas in mice and humans.

  7. We observed a significantly higher expression of GPR55 mRNA in Crohn's disease (CD) patients compared to ulcerative colitis (UC) and controls. CD patients manifested higher GPR55 mRNA expression in inflamed compared with non-inflamed colonic tissues. In contrast, the analysis of GPR55 mRNA expression in UC patients revealed no statistically significant differences between inflamed and non-inflamed colonic tissue.

  8. Crucial amino acid residues involved in agonist signaling at the GPR55 receptor have been identified.

  9. The signalling pathways activated by lysophosphatidylinositol through its receptor GPR55 play a pivotal role in different cancer. [review]

  10. GPR55 is involved in the migratory behaviour of colon carcinoma cells.

  11. Inhibiting the pro-angiogenic L-alpha-lysophosphatidylinositol /GPR55 pathway appears a promising target against angiogenesis in ovarian carcinoma

  12. GPR55 is expressed in placenta,located solely at the placental endothelium; L-alpha-lysophosphatidylinositol (LPI), the endogenous ligand of GPR55, increases migratory activity of venous but not arterial placental endothelial cells suggesting a role of LPI-GPR55 axis in placental venous endothelium function

  13. GPR55 could play deleterious role in ox-LDL-induced foam cells and could be a novel pharmacological target to manage atherosclerosis and other related cardiovascular diseases.

  14. GPR55 was a direct target gene of miR-675-5p.

  15. proinflammatory role in innate immunity

  16. expression of CB1 and GPR55 in proximal tubules is altered in response to elevated levels of glucose and albumin

  17. This review summarizes our current knowledge of expression and function of GPR55 in tissues involved in metabolic regulation and the signaling cascades through which GPR55 is reported to act.

  18. Heteromerization of GPR55 and cannabinoid CB2 receptors modulates signalling

  19. Data suggest GPR55 (G-protein coupled receptor 55), ABCC1 (ATP-binding cassette sub-family C), and MPR1/ABCB1 (multidrug resistance protein 1) participate/cooperate in autocrine communication/tumorigenesis involving lysophosphatidylinositol. [REVIEW]

  20. CB2R and GPR55 form heteromers in cancer cells, these structures possess unique signaling properties, and modulation of these heteromers can modify the antitumoral activity of cannabinoids in vivo

Mouse (Murine) G Protein-Coupled Receptor 55 (GPR55) interaction partners

  1. Our findings support the hypothesis that neural stem cells (NSC) express functional GPR55 and that targeting GPR55 with selective agonists increases NSC proliferation and early neurogenesis both in vitro and in vivo. A better understanding of the role GPR55 plays during neurogenesis may provide new prospects for therapeutic treatments utilizing this receptor as a target.

  2. findings identify GPR55 as a positive regulator of insulin action and adipogenesis and as a potential therapeutic target for countering obesity-induced metabolic dysfunction and insulin resistance

  3. GPR55 might be a therapeutic target for T2DM.

  4. Our results demonstrate the important role played by GPR55 ...in pancreatic ductal adenocarcinoma progression

  5. The study reveals changes in gene expression of members of the endocannabinoid system in situ attesting particularly GPR55 and MGL a distinct cellular role in the regulation of the immune response to intestinal and systemic inflammation.

  6. Genetic deletion of GPR55 did not alter the development of pathological pain in adult mice in any chronic pain model evaluated.

  7. GPR55 plays an important role in anxiety.

  8. This study demonstrated that the GPR55 modulates hippocampal synaptic plasticity.

  9. our data suggest that GPR55 and CB1 play differential roles in colon carcinogenesis where the former seems to act as oncogene and the latter as tumor suppressor.

  10. GPR55 was highly expressed by beta-cells of both humans and mice. It was also present in a small proportion of mouse islet alpha-cells and in the majority of human islet alpha-cells, but it was absent or at very low levels in delta-cells of both species. GPR55 was preferentially expressed in the endocrine pancreas, with only faint immunoreactivity in the exocrine pancreas in mice and humans.

  11. GPR55 agonist lysophosphatidylinositol and lysophosphatidylcholine inhibit endothelial cell hyperpolarization via GPR-independent suppression of Na(+)-Ca(2+) exchanger and endoplasmic reticulum Ca(2+) refilling.

  12. Gpr55 deficiency is associated with subtle effects on energy expenditure and motor activity behaviours but does not appear per se critically required for overall metabolism or behaviours

  13. GPR55 has an important role in energy homeostasis. GPR55 ablation increases adiposity and insulin resistance by selectively decreasing physical activity, but not by altering feeding behavior as CB1.

  14. Results indicate that GPR55 modulates the growth rate and the targets innervation of retinal projections and highlight, for the first time, an important role of GPR55 in axon refinement during development

  15. expression of CB1 and GPR55 in proximal tubules is altered in response to elevated levels of glucose and albumin

  16. Data show evidence of GPR55 involvement in central pain processing and unravel a novel Ca2+-mediated mechanism by which periaqueductal gray neurons are activated downstream of GPR55.

  17. Mice deficient in GPR55 exhibit maladaptive adrenergic signalling, as evidenced by the reduced contractile reserve.

  18. GPR55 is distributed in pancreatic beta cells and is a strong activator of insulin secretion, with glucose-lowering effects in vivo. Development of agents agonizing the GPR55 receptor may have therapeutic potential in the treatment of type 2 diabetes.

  19. Data (including data from knockout mice) suggest that GPR55 is strongly expressed on myenteric neurons of the colon and that GPR55 is selectively involved in the regulation of colonic motility.

  20. GPR55 plays a role in motor coordination, but does not strongly regulate CNS development, gross motor movement or several types of learned behavior.

GPR55 Antigen Profile

Protein Summary

Members of the G protein-coupled receptor (GPR) family, such as GPR55, play important roles in signal transduction from the external environment to the inside of the cell (Sawzdargo et al., 1999

Gene names and symbols associated with GPR55

  • G protein-coupled receptor 55 (GPR55) antibody
  • G protein-coupled receptor 55 (Gpr55) antibody
  • Gm218 antibody
  • GPR55 antibody

Protein level used designations for GPR55

G protein-coupled receptor 55 , G-protein coupled receptor 55

GENE ID SPECIES
470673 Pan troglodytes
539107 Bos taurus
9290 Homo sapiens
227326 Mus musculus
501177 Rattus norvegicus
770641 Gallus gallus
486157 Canis lupus familiaris
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