anti-G Protein-Coupled Receptor 77 (GPR77) Antibodies

The anaphylatoxins C3a (see MIM 120700), C4a (see MIM 120810), and C5a are cationic fragments generated during the complement cascade that participate in host defense. Additionally we are shipping G Protein-Coupled Receptor 77 Kits (3) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
GPR77 27202 Q9P296
GPR77 319430 Q8BW93
Anti-Rat GPR77 GPR77 445269  
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Top anti-G Protein-Coupled Receptor 77 Antibodies at antibodies-online.com

Showing 10 out of 104 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB WB Image Sample (30 ug of whole cell lysate) A: HeLa B: Molt-4 , 10% SDS PAGE antibody diluted at 1:1000 100 μL Log in to see 1 to 2 Days
$358.60
Details
Cow Rabbit Un-conjugated IHC, IHC (p), WB Human  Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE) Anti-C5L2 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml. 50 μg Log in to see 11 to 14 Days
$484.00
Details
Human Rabbit Un-conjugated IHC, IHC (p) Anti-C5L2 antibody IHC of human adrenal, adipocytes. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Log in to see 11 to 14 Days
$484.00
Details
Human Rabbit Un-conjugated IHC, IHC (p) Anti-C5L2 antibody IHC of human adrenal, adipocytes. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Log in to see 11 to 14 Days
$484.00
Details
Human Rabbit Un-conjugated WB GPR77 Antibody (C-term) (ABIN1881388) western blot analysis in A549 cell line lysates (35 µg/lane). This demonstrates the GPR77 antibody detected the GPR77 protein (arrow). 400 μL Log in to see 10 to 11 Days
$335.50
Details
Human Rabbit Un-conjugated ELISA, IHC, IHC (p) Human Brain, Cortex (formalin-fixed, paraffin-embedded) stained with GPR77 antibody ABIN213475 at 10 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. Anti-C5L2 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Log in to see 11 to 14 Days
$484.00
Details
Human Rabbit Un-conjugated ELISA, IHC, IHC (p) Human Brain, Cortex (formalin-fixed, paraffin-embedded) stained with GPR77 antibody ABIN213474 at 10 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. Anti-C5L2 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Log in to see 11 to 14 Days
$484.00
Details
Chimpanzee Rabbit Un-conjugated IHC (p), WB 50 μg Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IHC, ELISA 0.05 mg Log in to see 2 to 3 Days
$550.00
Details
Human Rabbit Un-conjugated IHC, ELISA 0.05 mg Log in to see 2 to 3 Days
$550.00
Details

More Antibodies against G Protein-Coupled Receptor 77 Interaction Partners

Human G Protein-Coupled Receptor 77 (GPR77) interaction partners

  1. Both rs2972607 and rs8112962 SNPs of C5L2 are associated with coronary artery disease in a Han population of China.

  2. Studies indicate that the complement response lie the active fragments, C3a (show C3 Antibodies) and C5a, acting through their specific receptors, C3aR (show C3AR1 Antibodies), C5aR1 (show C5AR1 Antibodies) and C5aR2 to direct the cellular response to inflammation.

  3. negative regulator of BDNF (show BDNF Antibodies) secretion by pulp fibroblasts under carious teeth

  4. All the C698T genotypes and allele frequencies in C5L2 were almost similar in both the cases and controls.

  5. C5AR (show C5AR1 Antibodies) and C5L2-mediated neutrophil dysfunction is associated with a poor outcome in sepsis.

  6. this study reveals a novel role for C5aR2 in C5a-mediated activation of mast cells and demonstrates that C5aR2 ligation initiates a beta (show SUCLA2 Antibodies)-arrestin-2 (show ARRB2 Antibodies)-, PI3K (show PIK3CA Antibodies)-, and ERK (show EPHB2 Antibodies)-dependent signaling pathway in these cells.

  7. C5a2 can modulate ERK1/2 signaling in macrophages via heteromer formation with C5a1 and beta-arrestin recruitment.

  8. prominent C5L2 expression in advanced atherosclerotic stages directly correlates with high levels of proinflammatory cytokines

  9. The present study has extended the mutation spectrum of C5L2, and Thr196Asn mutations in C5L2 were associated with retinitis pigmentosa and serum lipid levels.

  10. C5aR (show C5AR1 Antibodies) and C5L2 may have roles in adiposity in women

Mouse (Murine) G Protein-Coupled Receptor 77 (GPR77) interaction partners

  1. The role of C5aR1 (show C5AR1 Antibodies) and C5aR2 in response to renal ischemia-reperfusion injury is reported. The results also demonstrated that C5aR2 is a functional receptor, rather than a decoy receptor, and may provide a new target for intervention.

  2. C5L2 plays an important antiinflammatory role.

  3. Findings demonstrate that, under excitotoxicity, Fosb (show FOSB Antibodies) products contribute to a neuroinflammatory response in the hippocampus through regulation of microglial C5ar1 (show C5AR1 Antibodies) and C5ar2 expression

  4. This work reveals an essential role for C5L2 in C5a-triggered, AP2 (show TFAP2A Antibodies)-dependent C5aR (show C5AR1 Antibodies) internalization and downstream ERK (show EPHB2 Antibodies) signaling.

  5. Mouse susceptibility to MHV-3-induced fulminant hepatitis may rely on C5a/C5aR interactions, for which ERK1/2 and p38 (show CRK Antibodies) pathways participate in up-regulating Fgl2 (show FGL2 Antibodies) expression.

  6. These observations indicate the importance of C5aR (show C5AR1 Antibodies) in adipose tissue metabolism and immunity, which may be regulated through heterodimerization with C5L2.

  7. in allergic contact sensitivity, as in isolated human neutrophils, C5L2 functions to suppress C5a-C5aR-mediated responses, further underscoring its role as a negative regulator of anaphylatoxin activity.

  8. Disruption of C5L2 increases macrophage presence in white adipose tissue, contributing to obesity-associated pathologies.

  9. C5L2 is a functional receptor for ASP (show C3 Antibodies) and act as a decoy receptor for C5a in pathophysiological conditions.

  10. These findings elucidate the functional characteristics of the C5L2 receptor during the acute inflammatory response.

G Protein-Coupled Receptor 77 (GPR77) Antigen Profile

Protein Summary

This gene encodes a G-protein coupled receptor 1 family member involved in the complement system of the innate immune response. Unlike classical G-protein coupled receptors, the encoded protein does not associate with intracellular G-proteins. It may instead modulate signal transduction through the beta-arrestin pathway, and may alternatively act as a decoy receptor. This gene may be involved in coronary artery disease and in the pathogenesis of sepsis. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with GPR77

  • complement component 5a receptor 2 (C5AR2) antibody
  • complement component 5a receptor 2 (C5ar2) antibody
  • C5L2 antibody
  • E030029A11Rik antibody
  • GPF77 antibody
  • Gpr77 antibody

Protein level used designations for GPR77

G protein-coupled receptor 77 , G protein-coupled receptor C5L2 , C5a anaphylatoxin chemotactic receptor 2 , C5a anaphylatoxin chemotactic receptor C5L2 , G-protein coupled receptor 77 , C5A receptor beta , complement 5A receptor beta

GENE ID SPECIES
456162 Pan troglodytes
612145 Canis lupus familiaris
717209 Macaca mulatta
27202 Homo sapiens
319430 Mus musculus
445269 Rattus norvegicus
522144 Bos taurus
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