G Protein-Coupled Receptor 183 (GPR183) ELISA Kits

GPR183 was identified by the up-regulation of its expression upon Epstein-Barr virus infection of primary B lymphocytes. Additionally we are shipping GPR183 Antibodies (38) and GPR183 Proteins (3) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human GPR183 GPR183 1880 P32249
Anti-Mouse GPR183 GPR183 321019 Q3U6B2
Anti-Rat GPR183 GPR183 679975  
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More ELISA Kits for GPR183 Interaction Partners

Zebrafish G Protein-Coupled Receptor 183 (GPR183) interaction partners

  1. Inhibition of Gpr183 significantly upregulates Notch (show NOTCH1 ELISA Kits) signaling and abolishes embryonic hematopoietic stem and progenitor cells emergence.

Human G Protein-Coupled Receptor 183 (GPR183) interaction partners

  1. Studies provide evidence that EBI2 and oxysterols are important players not only in the immune system but also in the central nervous system. Proper functioning of the EBI2/oxysterol system seems crucial for healthy physiology and prevention of the onset or progression of several neurodegenerative diseases. [review]

  2. Human EBI2 (GPR183) expression in mice leads to an abnormally expanded CD5 (show CD5 ELISA Kits)+ B1a B-cell subset and chronic lymphocytic leukemia-like B-cell malignancies.

  3. On ligand engagement, EBI2 typically signals via inhibitory G-protein subunit alpha to induce intracellular calcium mobilization, mitogen-activated protein kinase (show MAPK1 ELISA Kits) (MAPK (show MAPK1 ELISA Kits)) activation, and cell proliferation.

  4. this study concludes that EBI2 expression is directly influenced by EBV infection and that BRRF1 is necessary and sufficient for EBI2 upregulation during infection.

  5. These results demonstrate a role for EBI2 in astrocyte function and suggest that modulation of this receptor may be beneficial in neuroinflammatory disorders.

  6. EBI2 is expressed in primary human monocytes and macrophages.

  7. This model of ligand docking yields important structural insight into the molecular mechanisms mediating EBI2 function.

  8. Data indicate that EBI2 expression modulates CXCL13 (show CXCL13 ELISA Kits) binding affinity to CXCR5 (show CXCR5 ELISA Kits).

  9. Molecular characterization of oxysterol binding to the Epstein-Barr virus-induced gene 2 (GPR183).

  10. Based on the constitutive signaling and cellular expression pattern of EBI2, it is suggested that it may function in conjunction with BILF1 in the reprogramming of the cell during EBV infection

Mouse (Murine) G Protein-Coupled Receptor 183 (GPR183) interaction partners

  1. These data identify a role for EBI2 in promoting efficient thymic central tolerance.

  2. mice lacking EBI2 in T cells or CD25 (show IL2RA ELISA Kits) in dendritic cells have reduced T follicular helper cells and mount defective T-cell-dependent plasma cell and germinal centre responses

  3. findings establish an essential role for EBI2 in CD4 (show CD4 ELISA Kits)(+) DC positioning and homeostasis and in facilitating capture and presentation of blood-borne particulate antigens

  4. EBI2 is a negative regulator of type I interferons in plasmacytoid and myeloid dendritic cells.

  5. Regulated expression of EBI2 on DC populations is therefore critical for the generation and correct positioning of splenic DCs and the initiation of immune responses.

  6. Regulation of B cell migration by EBI2 has an important role in controlling the positioning of activated B cells within lymphoid follicles in the early phases of B cell responses during cell differentiation and affinity maturation.

  7. These findings establish a role for EBI2 in helping control B cell position at multiple stages during the Ab response

  8. ligand targeting EBI2. In turn, this molecule provides a useful tool for further characterization of EBI2 as well as serving as a potent lead compound.

  9. important role for EBI2 in promoting B cell localization in the outer follicle, and show that differential expression of this receptor helps position B cells appropriately for mounting T-dependent antibody responses

  10. EBI2 provides a previously uncharacterized dimension to B (show TDO2 ELISA Kits) cell migration that is crucial for coordinating rapid versus long-term antibody responses.

GPR183 Antigen Profile

Antigen Summary

This gene was identified by the up-regulation of its expression upon Epstein-Barr virus infection of primary B lymphocytes. This gene is predicted to encode a G protein-coupled receptor that is most closely related to the thrombin receptor. Expression of this gene was detected in B-lymphocyte cell lines and lymphoid tissues but not in T-lymphocyte cell lines or peripheral blood T lymphocytes. The function of this gene is unknown.

Gene names and symbols associated with GPR183

  • G protein-coupled receptor 183 (GPR183) antibody
  • G protein-coupled receptor 183a (gpr183a) antibody
  • EBV-induced G-protein coupled receptor 2 (ebi2) antibody
  • G protein-coupled receptor 183 (Gpr183) antibody
  • G protein-coupled receptor 183-like (LOC615640) antibody
  • Ebi2 antibody
  • gpr183 antibody
  • gpr183a antibody
  • zgc:165579 antibody

Protein level used designations for GPR183

G protein-coupled receptor 183 , EBV-induced G protein-coupled receptor 2 , Epstein-Barr virus induced gene 2 (lymphocyte-specific G protein-coupled receptor) , G-protein coupled receptor 183 , Epstein-Barr virus induced gene 2 , G-protein coupled receptor 183-A , G-protein coupled receptor 183-like , EBV-induced G-protein coupled receptor 2 , epstein-Barr virus-induced G-protein coupled receptor 2 , EBV-induced G-protein coupled receptor 2 homolog

GENE ID SPECIES
467308 Pan troglodytes
540287 Bos taurus
556770 Danio rerio
698844 Macaca mulatta
100388743 Callithrix jacchus
100452504 Pongo abelii
100195196 Salmo salar
1880 Homo sapiens
321019 Mus musculus
679975 Rattus norvegicus
615640 Bos taurus
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