GDP Dissociation Inhibitor 1 Proteins (GDI1)

GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. Additionally we are shipping GDP Dissociation Inhibitor 1 Antibodies (88) and GDP Dissociation Inhibitor 1 Kits (35) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
GDI1 2664 P31150
GDI1 14567 P50396
GDI1 25183 P50398
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Top GDP Dissociation Inhibitor 1 Proteins at antibodies-online.com

Showing 10 out of 14 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$9,626.73
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$9,626.73
Details
Escherichia coli (E. coli) Human His tag 50 μg Log in to see 13 to 16 Days
$492.31
Details
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$325.44
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see Available
$814.00
Details
Yeast Chimpanzee His tag   1 mg Log in to see 60 to 71 Days
$3,254.17
Details
Yeast Cynomolgus His tag   1 mg Log in to see 60 to 71 Days
$3,254.17
Details
Yeast Rat His tag   1 mg Log in to see 60 to 71 Days
$3,254.17
Details
Yeast Cow His tag   1 mg Log in to see 60 to 71 Days
$3,254.17
Details
Yeast Dog His tag   1 mg Log in to see 60 to 71 Days
$3,254.17
Details

GDI1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, , ,
Mouse (Murine)

Rat (Rattus)

Top referenced GDP Dissociation Inhibitor 1 Proteins

  1. Human GDI1 Protein expressed in Wheat germ - ABIN1354977 : Kimura, Kanoh, Sakurai, Koumura, Yamada, Hayashi, Tanaka, Hozumi, Takemura, Seishima, Inuzuka: Antibodies in patients with neuropsychiatric systemic lupus erythematosus. in Neurology 2010 (PubMed)

More Proteins for GDP Dissociation Inhibitor 1 (GDI1) Interaction Partners

Human GDP Dissociation Inhibitor 1 (GDI1) interaction partners

  1. Data confirm isolated adrenocorticotropin deficiency (IAD) as autoimmune disease; RABGDIA (human, human recombinant, or rat) exhibits characteristics of autoantigen in anterior pituitary; patients with IAD exhibit autoantibodies against RABGDIA.

  2. Human oligodendrogliomas cells stably expressing mutant GDI1 showed altered cell proliferation.

  3. The results of this study identified RabGDI as a component of the switching mechanism that is required for commissural axons to change their response from attraction to repulsion at the intermediate target

  4. GDI1 mutations cause an unspecific phenotype characterized by cognitive deficits of variable degree in males, and to a lesser degree in female carriers.

  5. The mutations in this gene are common and do not seem to influence the gene expression so as to cause a change in phenotype.

  6. A model by which mutant PrP induces overexpression of GDI, activating a cytotoxic feedback loop that leads to protein accumulation in the secretory pathway.

  7. This protein has been found differentially expressed in the anterior cingulate cortex from patients with schizophrenia

  8. RhoGDI has a role in inactivating Rho GTPases with ExoS RhoGAP

  9. isoprenylcysteine carboxylmethyltransferase regulates Rac1 activity by controlling the interaction of Rac1 with RhoGDI through TNFA

  10. RhoGDI overexpression is associated with paclitaxel resistance in ovarian cancers

  11. The results of case-control analysis indicated that, no association between the rs11549300 polymorphisms of GDI1 and children NSMR (P >0.05), but its polymorphisms may be related to intelligence levels of children in Qinba region (P =0.03).

  12. GDI-1 is preferentially involved in insulin-stimulated glucose transporter 4 (GLUT4) translocation through facilitating Rab10 recycling.

Mouse (Murine) GDP Dissociation Inhibitor 1 (GDI1) interaction partners

  1. Study used cognitive protocols with high translational validity to human condition that target the functionality of cortico-striatal circuitry such as attention and stimulus selection ability with progressive degree of complexity; showed that that Gdi1-null mice are impaired in attention and associative learning processes.

  2. Data confirm isolated adrenocorticotropin deficiency (IAD) as autoimmune disease; RABGDIA/Gdi1 (human or rat) exhibits characteristics of autoantigen in anterior pituitary; patients with IAD exhibit autoantibodies against RABGDIA/Gdi1.

  3. A pivotal role of alphaGDI via specific RAB GTPases acting specifically in forebrain regions at the pre-synaptic sites involved in memory formation.

  4. Lack of alphaGDI impairs synaptic vesicle biogenesis and recycling in the hippocampus.

GDP Dissociation Inhibitor 1 (GDI1) Protein Profile

Protein Summary

GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound rabs. GDI1 is expressed primarily in neural and sensory tissues. Mutations in GDI1 have been linked to X-linked nonspecific mental retardation.

Gene names and symbols associated with GDI1

  • GDP dissociation inhibitor 1 (GDI1)
  • GDP dissociation inhibitor 1 S homeolog (gdi1.S)
  • guanosine diphosphate (GDP) dissociation inhibitor 1 (Gdi1)
  • GDP dissociation inhibitor 1 (Gdi1)
  • GDP dissociation inhibitor 1 (gdi1)
  • 1A protein
  • GDI-1 protein
  • GDIA protein
  • GDIalpha protein
  • GDIL protein
  • MRX41 protein
  • MRX48 protein
  • OPHN2 protein
  • QccE-14779 protein
  • RABGD1A protein
  • RABGDIA protein
  • Rab GDI alpha protein
  • XAP-4 protein
  • zgc:110600 protein

Protein level used designations for GDI1

GDI-1 , guanosine diphosphate dissociation inhibitor 1 , mental retardation, X-linked 48 , oligophrenin-2 , protein XAP-4 , rab GDI alpha , rab GDP dissociation inhibitor alpha , rab GDP-dissociation inhibitor, alpha , Rab GDIalpha , GDP-dissociation inhibitor 1 , SMG p25A GDI , Guanosine diphosphate dissociation inhibitor 1 , Rab GDI alpha

GENE ID SPECIES
2664 Homo sapiens
447577 Xenopus laevis
14567 Mus musculus
25183 Rattus norvegicus
403819 Canis lupus familiaris
281188 Bos taurus
100328761 Oryctolagus cuniculus
450155 Pan troglodytes
100173688 Pongo abelii
100723872 Cavia porcellus
100302074 Ovis aries
554985 Danio rerio
102142996 Macaca fascicularis
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