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GRIPAP1 encodes a guanine nucleotide exchange factor for the Ras family of small G proteins (RasGEF).
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Human Polyclonal GRIPAP1 Primary Antibody for ELISA - ABIN250234
Ye, Liao, Zhang, Zhang, Dong, Huganir: GRASP-1: a neuronal RasGEF associated with the AMPA receptor/GRIP complex. in Neuron 2000
We identified a new TFE3 (show TFE3 Antibodies) fusion partner, GRIPAP1, in translocation renal cell carcinoma (show MOK Antibodies)
results demonstrate a requirement for normal recycling endosome function in AMPAR-dependent synaptic function and neuronal connectivity in vivo, and suggest a potential role for GRASP1 in the pathophysiology of human cognitive disorders.
GRASP-1 was identified as an soluble autoantigen that has numerous coiled-coil domains throughout the protein.
Results suggest that GRASP-1 serves as a scaffold protein (show HOMER1 Antibodies) to facilitate MEKK-1 (show MAP3K1 Antibodies) activation of JNK (show MAPK8 Antibodies) signaling in neurons.
This gene encodes a guanine nucleotide exchange factor for the Ras family of small G proteins (RasGEF). In brain studies, the encoded protein was found with the GRIP/AMPA receptor complex. Multiple alternatively spliced transcript variants have been described that encode different protein isoforms\; however, the full-length nature and biological validity of all of these variants have not been determined.
GRIP1 associated protein 1
, GRIP1-associated protein 1
, GRIP1-associated protein 1-like
, HCMV-interacting protein
, GRIP-associated protein 1