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GTP-binding proteins, or G proteins, constitute a superfamily capable of binding GTP or GDP. Additionally we are shipping GTPBP2 Antibodies (56) and GTPBP2 Kits (4) and many more products for this protein.
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Biallelic inactivating variants in the GTPBP2 were identified in two patients with severe intellectual disability and structural brain abnormalities.
GTPBP2 lacked elongation activity and did not stimulate exosomal degradation, indicating that GTPBP1 and GTPBP2 have different functions.
It may be a novel neurodegeneration with brain iron accumulation gene.
these results not only define GTPBP2 as a ribosome rescue factor but also unmask the disease potential of mutations in nuclear-encoded tRNA genes.
Gtpbp2 is required for BMP signaling and mesoderm patterning in Xenopus embryos.
GTP-binding proteins, or G proteins, constitute a superfamily capable of binding GTP or GDP. G proteins are activated by binding GTP and are inactivated by hydrolyzing GTP to GDP. This general mechanism enables G proteins to perform a wide range of biologic activities.
GTP-binding protein 2
, GTP-binding-like protein 2
, GTP binding protein beta subunit
, guanine nucleotide-binding protein subunit beta
, hypothetical protein