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mouse homolog is induced by dioxin and may play a role in spermatogenesis [RGD, Feb 2006]..
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Results identified GGNBP2 as a novel tumor suppressor which is downregulated in human breast tumors and cell lines and suggest that GGNBP2 may function as a corepressor to inhibit ERa's transcriptional activity and consequently inhibit tumorigenic potential of breast cancer cells.
The effects of ZFP403 on cell proliferation and metastasis suggest that it may serve as a tumor suppressor in ovarian cancer.
Results show that downregulation of RNASET2 (show RNASET2 Proteins) and GGNBP2 in drug-resistant ovarian cancer tissues/cells contributes to the regulation of drug resistance in ovarian cancer.
There is an essential role for ZNF403 in cell proliferation and G2/M cell-cycle transition.
LCRG1 is a novel gene localized to the tumor suppressor locus D17S800-D17S930 involved in laryngeal carcinoma.
demonstrates that GGNBP2 is critically required for maintenance of the adhesion integrity of the adlumenal germ epithelium and is indispensable for normal spermatid transformation into mature spermatozoa in mice
GGNBP2 is an essential factor for pregnancy success acting through the maintenance of a balance of trophoblast stem cell proliferation and differentiation during placental development.
Ggnbp2 is mainly expressed in the testis. Its protein product interacted with GGN1 and could be involved in intracellular trafficking.
mouse homolog is induced by dioxin and may play a role in spermatogenesis
C3HC4-type zinc finger protein
, gametogenetin-binding protein 2
, laryngeal carcinoma related gene 1
, laryngeal carcinoma-related protein 1
, zinc finger protein 403
, dioxin inducible factor 3
, dioxin-inducible factor 3
, gametogenin binding protein 2
, gametogenetin binding protein 2
, gametogenetin-binding protein 2-like