Glial Fibrillary Acidic Protein Proteins (GFAP)

GFAP encodes one of the major intermediate filament proteins of mature astrocytes. Additionally we are shipping GFAP Antibodies (953) and GFAP Kits (81) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
GFAP 2670 P14136
GFAP 24387 P47819
GFAP 14580 P03995
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Top GFAP Proteins at antibodies-online.com

Showing 10 out of 38 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$5,465.26
Details
Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$5,465.26
Details
Escherichia coli (E. coli) Mouse His tag,GST tag 100 μg Log in to see 15 to 18 Days
$544.00
Details
Escherichia coli (E. coli) Human His tag   50 μg Log in to see 4 Days
$522.50
Details
Escherichia coli (E. coli) Human His tag Validation with Western Blot 10 μg Log in to see 8 to 11 Days
$504.90
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see Available
$814.00
Details
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$414.29
Details
Escherichia coli (E. coli) Human His tag 100 μg Log in to see 15 to 18 Days
$560.00
Details
Yeast Cow His tag   1 mg Log in to see 60 to 71 Days
$3,193.67
Details
Yeast Orang-Utan His tag   1 mg Log in to see 60 to 71 Days
$3,206.50
Details

GFAP Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Rat (Rattus) ,
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Mouse (Murine) ,
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More Proteins for Glial Fibrillary Acidic Protein (GFAP) Interaction Partners

Rhesus Monkey Glial Fibrillary Acidic Protein (GFAP) interaction partners

  1. There was significantly more GFAP immunoreactivity in the prefrontal cortex and hippocampus of aged animals compared to adult or middle-aged animals.

Human Glial Fibrillary Acidic Protein (GFAP) interaction partners

  1. Desmin (show DES Proteins), Glial Fibrillary Acidic Protein, Vimentin (show VIM Proteins), and Peripherin (show PRPH Proteins) are type III intermediate filaments that have roles in health and disease [review]

  2. Plasma concentration of GFAP demonstrated associations with stroke occurrence in a West African cohort but was not associated with stroke severity or mortality.

  3. This study demonstrated that Concentrations of microparticles expressing GFAP and AQP4 (show AQP4 Proteins) were significantly higher in the traumatic brain injury group compared with healthy controls.

  4. The authors observed higher serum levels of GFAP and UCH-L1 (show UCHL1 Proteins) in brain-injured children compared with controls and also demonstrated a step-wise increase of biomarker concentrations over the continuum of severity from mild to severe traumatic brain injury. Serum UCH-L1 (show UCHL1 Proteins) and GFAP concentrations also strongly predicted poor outcome.

  5. Study examined if QKI6B expression can predict the outcome of GFAP, and several oligodendrocyte-related genes, in the prefrontal cortex of brain samples of schizophrenic individuals. QKI6B significantly predicts the expression of GFAP, but does not predict oligodendrocyte-related gene outcome, as previously seen with other QKI (show QKI Proteins) isoforms.

  6. GFAP, along with tau and AmyloidBeta42, were increased in plasma up to 90 days after traumatic brain injury compared with controls.

  7. Results show that the positive rates and expression levels of nestin (show NES Proteins), tyrosine hydroxylase (TH (show TH Proteins)), GFAP and IL-17 (show IL17A Proteins) were significantly decreased while Foxp3 (show FOXP3 Proteins) and the ratio of Foxp3 (show FOXP3 Proteins)/IL-17 (show IL17A Proteins) were statistically elevated in BM of AML (show RUNX1 Proteins) patients.

  8. GFAP levels >0.29 ng/ml were seen only in intracerebral hemorrhage, thus confirming the diagnosis of ICH (show COL4a2 Proteins) during prehospital care.

  9. These results indicate that autoantibodies against GFAP could serve as a predictive marker for the development of overt autoimmune diabetes.

  10. Higher median plasma GFAP values were documented in intracerebral hemorrhage compared with acute ischemic stroke, stroke mimics, and controls.

Pig (Porcine) Glial Fibrillary Acidic Protein (GFAP) interaction partners

  1. Isolation of an evolutionary conserved novel GFAP isoform, GFAPkappa, produced by alternative splicing and polyadenylation of the 3'-region of the human GFAP pre-mRNA is described.

Mouse (Murine) Glial Fibrillary Acidic Protein (GFAP) interaction partners

  1. This report the successful prediction and validation of Gfap as an miR (show MLXIP Proteins)-3099 target gene using a combination of bioinformatics resources with enrichment of annotations based on functional ontologies and a spatio-temporal expression dataset.

  2. These results indicate that autoantibodies against GFAP could serve as a predictive marker for the development of overt autoimmune diabetes.

  3. GFAP is specifically expressed in the auricular chondrocytes, and assumes a pivotal role in resistance against mechanical stress.

  4. compared open-skull and thinned-skull imaging methods for two-photon laser microscopy of live astrocytes in neocortex of GFAP-GFP transgenic mice

  5. work reveals that an Alexander disease-causing mutation alters GFAP turnover kinetics in vivo and provides an essential foundation for future studies aimed at preventing or reducing the accumulation of GFAP.

  6. Tat (show TAT Proteins) expression or GFAP expression led to formation of GFAP aggregates and induction of unfolded protein response (UPR) and endoplasmic reticulum (ER) stress in astrocytes.

  7. Study provides evidence that transcription of one of the astrocyte-specific genes, Gfap, is cooperatively regulated by co-expressed genes and their regulatory factors.

  8. This study demonstrated the GFAP-ApoE4 mice exhibited motor impairments when compared to GFAP-ApoE3 and wild-type mice.

  9. PINK1 (show PINK1 Proteins) deficiency causes defects in GFAP-positive astrogliogenesis during brain development.

  10. Gnasxl (show GNAS Proteins) deficiency does not directly affect glial development in the hypothalamus, since it is expressed in neurons, and Gfap-positive astrocytes and tanycytes appear normal during early postnatal stages.

Zebrafish Glial Fibrillary Acidic Protein (GFAP) interaction partners

  1. Aggregation-prone GFAP mutation in Alexander disease was validated using a zebrafish model; The p.Asp128Asn GFAP mutation is likely to be a disease-causing mutation

  2. The distribution of GFAP immunoreactivity implies that enteric glia are widespread in the fish gastrointestinal tract.

  3. Generation of transgenic zebrafish that express green fluorescent protein (GFP) in glial cells driven by the zebrafish glial fibrillary acidic protein (GFAP) regulatory elements.

  4. Cells expressing the two reporters display radial glial morphology, colocalize with the NSC marker Sox2 (show SOX2 Proteins), undergo proliferation, and are capable of self-renewal within the matrix of distinct thickness in the telencephalon.

GFAP Protein Profile

Protein Summary

This gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Gene names and symbols associated with GFAP

  • glial fibrillary acidic protein (GFAP)
  • glial fibrillary acidic protein (LOC100136168)
  • glial fibrillary acidic protein (gfap)
  • glial fibrillary acidic protein (Gfap)
  • AI836096 protein
  • cb345 protein
  • etID36982.3 protein
  • GFAP protein
  • gfapl protein
  • wu:fb34h11 protein
  • wu:fk42c12 protein
  • xx:af506734 protein
  • zgc:110485 protein

Protein level used designations for GFAP

glial fibrillary acidic protein , glial fibrillary acidic protein alpha , intermediate filament , intermediate filament protein , zrf-1 antigen

GENE ID SPECIES
712941 Macaca mulatta
454741 Pan troglodytes
100136168 Oncorhynchus mykiss
100534495 Oreochromis niloticus
2670 Homo sapiens
24387 Rattus norvegicus
100720409 Cavia porcellus
101081938 Felis catus
396562 Sus scrofa
281189 Bos taurus
14580 Mus musculus
100352532 Oryctolagus cuniculus
419969 Gallus gallus
480495 Canis lupus familiaris
443220 Ovis aries
30646 Danio rerio
100172719 Pongo abelii
100033970 Equus caballus
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