Granzyme B Proteins (GZMB)

Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. Additionally we are shipping Granzyme B Antibodies (289) and Granzyme B Kits (84) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
GZMB 3002 P10144
GZMB    
GZMB    
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top Granzyme B Proteins at antibodies-online.com

Showing 10 out of 38 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HEK-293 Cells Mouse Un-conjugated 25 μg Log in to see 10 to 12 Days
$438.71
Details
HEK-293 Cells Human Un-conjugated 25 μg Log in to see 10 to 12 Days
$438.71
Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$6,749.58
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$6,749.58
Details
HEK-293 Cells Human His tag 10 μg Log in to see 2 to 3 Days
$385.00
Details
Human Cells Human His tag 10 μg Log in to see 14 to 16 Days
$285.35
Details
Escherichia coli (E. coli) Mouse His tag,GST tag 100 μg Log in to see 15 to 18 Days
$704.00
Details
Human Cells Mouse His tag   50 μg Log in to see 4 Days
$522.50
Details
Insect Cells Mouse Un-conjugated 5 μg Log in to see 2 to 3 Days
$315.00
Details
Insect Cells Human Un-conjugated 5 μg Log in to see 2 to 3 Days
$335.00
Details

GZMB Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , , , ,
, , ,
Mouse (Murine) , , , ,
,
Rat (Rattus) ,

More Proteins for Granzyme B (GZMB) Interaction Partners

Human Granzyme B (GZMB) interaction partners

  1. our exploratory study suggests that EOMES, BCL6 and GZMB gene expression are aberrant within the PB T cell transcriptome of HT patients. The association of this transcription signature with the heterogeneity of HT and disease control is suggested.

  2. Serum interleukin 1 receptor antagonist (IL1RA) and granzyme B (GZMB) levels were markedly increased in Crohn's disease (CD) patients, suggesting that these markers can serve as biomarkers to identify gut inflammation.

  3. Authors found that R(48)-GzmB is a stable protein that accumulates to similar levels in activated NK cells as Q(48)-GzmB. rs8192917 polymorphism may influence antitumor activity and the effect of antitumor cellular immunotherapy.

  4. GzmA and gzmB were predominantly expressed by natural killer cells, and during abdominal sepsis, the percentage of these cells expressing gzms in peritoneal lavage fluid decreased, while the amount of expression in the gzm(+) cells increased

  5. Study provides evidence that Il10 expression is limited to migratory CD25++ regulatory T cells only.

  6. Long-term lung function decline in asthma is associated with elevation of bronchial CD8 and CD4 at baseline, and CD8, CD3 and granzyme B at follow-up

  7. Granzyme B breaches the inner membrane through Tim22, the metabolite carrier translocase pore, in a mitochondrial heat-shock protein 70-dependent manner.

  8. Differential proteomics were used to identify granzyme B substrates in three unrelated bacteria: Escherichia coli, Listeria monocytogenes, and Mycobacteria tuberculosis. Granzyme B cleaves a highly conserved set of proteins in all three bacteria, which function in vital biosynthetic and metabolic pathways that are critical for bacterial survival under diverse environmental conditions.

  9. Proteolysis by granzyme B enhances presentation of autoantigenic PAD4 epitopes in rheumatoid arthritis.

  10. our results suggest granzyme B PET imaging can serve as a quantitatively useful predictive biomarker for efficacious responses to cancer immunotherapy.

  11. Plasma GzmB levels may reflect the degree of pruritus and dermatitis in patients with atopic dermatitis

  12. These results suggest the critical importance of miR-378 in the regulation of GrzB expression and a protective role for GrzB in controlling dengue virus replication in vivo.

  13. Analysis of infiltrating granzyme B-expressing T cells at the invasive borders of the colon tumors revealed a significant difference in expression granzyme by race underlining decreased antitumor cytotoxic immunity in African Americans.

  14. Increased TIM3+CD8+T cells with lower perforin and granzyme B expression and higher CD95 expression in MDS patients were observed.

  15. Carbamate pesticides significantly reduced the intracellular levels of perforin, GrA, GrB, Gr3/K, and GRN in NK-92CI cells.

  16. granzyme-B levels were found to be significantly associated with increased insulin resistance in adolescent polycystic ovary syndrome patients. Additionally, elevated levels of serum granzyme-B were predictive for increased cardiovascular risk in PCOS patients

  17. results suggest that enhanced IL-21R expression of CD19(+)CD5(+) B cells and production of IL-21 by iNKT cells may play an important role in the pathogenesis of pSS by regulating CD19(+)CD5(+) B cell functions and increasing GrB production, presumably leading to a counter-regulatory effect in the disease.

  18. Findings show that GrB was produced in 57.1% colorectal cancer cell (CRC) lines and 100% CRC-derived Cancer Stem Cells and present a novel role for GrB as up-modulator of epitelial-to-mesenchimal transition in CRC cells.

  19. FASL, granzyme B, and cytochrome c blood expression reflects breast cancer progression and response to therapy. (Review)

  20. Data show that NK cell lines could secreted rapidly inactive Mr 35 000 granzyme B (GZB)outside secretory lysosomes (SLs).

Granzyme B (GZMB) Protein Profile

Protein Summary

Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein encoded by this gene is crucial for the rapid induction of target cell apoptosis by CTL in cell-mediated immune response.

Gene names and symbols associated with Granzyme B Proteins (GZMB)

  • granzyme B (GZMB)
  • CCPI protein
  • CGL-1 protein
  • CGL1 protein
  • CSP-B protein
  • CSPB protein
  • CTLA1 protein
  • CTSGL1 protein
  • HLP protein
  • SECT protein

Protein level used designations for Granzyme B Proteins (GZMB)

C11 , CTLA-1 , T-cell serine protease 1-3E , cathepsin G-like 1 , cytotoxic T-lymphocyte proteinase 2 , cytotoxic serine protease B , fragmentin 2 , fragmentin-2 , granzyme B , human lymphocyte protein

GENE ID SPECIES
3002 Homo sapiens
Selected quality suppliers for Granzyme B Proteins (GZMB)
Did you look for something else?