Growth Arrest-Specific 1 Proteins (GAS1)

Growth arrest-specific 1 plays a role in growth suppression.

list all proteins Gene Name GeneID UniProt
Human GAS1 GAS1 2619 P54826
Mouse GAS1 GAS1 14451 Q01721
Rat GAS1 GAS1 683470  
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Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days

More Proteins for Growth Arrest-Specific 1 (GAS1) Interaction Partners

Human Growth Arrest-Specific 1 (GAS1) interaction partners

  1. Studies establish Gas1 as a negative regulator in colorectal cancer.

  2. These results demonstrated that miR (show MLXIP Proteins)-184 and the GAS1/Akt (show AKT1 Proteins) pathway may be a potential therapeutic target for intervertebral disc degeneration.

  3. WT1 (show WT1 Proteins) modulates Akt (show AKT1 Proteins)/JNK (show MAPK8 Proteins) signaling pathway mediated autophagy by controlling the expression of growth arrest-specific 1 (Gas1).

  4. Downregulation of GAS1 is associated with clear cell renal cell carcinoma (show MOK Proteins).

  5. the synergistic effect of Gas1 inhibition and GDNF against glutamate (show GRIN1 Proteins)-induced cell injury in human SH-SY5Y neuroblastoma (show ARHGEF16 Proteins) cells, is reported.

  6. solutions structure and biophysical characterization of the multifaceted signalling effector protein growth arrest specific-1

  7. This review summarizes the structure of Gas1 and molecular mechanism of action during embryonic development and cellular functions.

  8. GAS1 is a novel endogenous inhibitor of glomerular mesangial cell proliferation.

  9. Growth arrest-specific gene 1 is downregulated and inhibits tumor growth in gastric cancer.

  10. GAS1 induced the activity of caspase-3 (show CASP3 Proteins) and resulting in apoptosis of the cells.

Mouse (Murine) Growth Arrest-Specific 1 (GAS1) interaction partners

  1. Western blot and immunofluorescence analyses showed two GIP (show GIP Proteins)-anchored proteins were clearly involved in the fertilisation process, namely growth arrest specific 1 (Gas1) and glial cell line-derived neurotrophic factor receptor alpha1 (Gfralpha1 (show GFRA1 Proteins)). This was demonstrated by evaluating oocyte fertilisability after treatment of oocytes with antibodies against the selected proteins, with their respective short interference RN...

  2. Findings provide evidence for a dual requirement for Boc (show BOC Proteins) and Gas1 during early development of the palate, mediating cell cycle regulation during growth and subsequent fusion of the palatal shelves.

  3. The results suggest that in diabetes the decrease of Gas1 promotes the activation of parietal progenitor cells of Bowman's capsule that might differentiate into podocytes and compensate their loss observed in this pathology.

  4. Up-regulation of inducible Gas1 contributed to the apoptosis of reactive astrocytes in injured substantia nigra.

  5. The C/EBP (show CEBPA Proteins) target Gas1 is induced in granulosa cells and is associated with ovulation and luteinization.

  6. the overexpression of Gas1 (growth arrest specific 1) gene reduces the size, proliferating activity and malignancy of liver tumors.

  7. WT1 (show WT1 Proteins) modulates receptor tyrosine kinase (show ERBB3 Proteins) signaling in nephron progenitor cell by directing the expression of Gas1.

  8. When Shh (show SHH Proteins) is presented as a point source, enteric axons turn away from it in a Gas1-dependent manner.

  9. widespread distribution and cellular localization of the GAS1 native protein in adult mammalian CNS

  10. finding that Gas1 is transcribed at the G(1)/S transition suggests that the gene may exert a novel function during cell proliferation.

GAS1 Protein Profile

Protein Summary

Growth arrest-specific 1 plays a role in growth suppression. GAS1 blocks entry to S phase and prevents cycling of normal and transformed cells. Gas1 is a putative tumor suppressor gene.

Gene names and symbols associated with GAS1

  • growth arrest specific 1 (GAS1)
  • growth arrest specific 1 (Gas1)
  • growth arrest specific 1 (gas1)
  • growth arrest-specific 1 (GAS1)
  • growth arrest-specific 1 (Gas1)
  • AW554192 protein
  • Gas-1 protein
  • MGC147541 protein

Protein level used designations for GAS1

GAS-1 , Growth arrest-specific gene-1 , growth arrest-specific protein 1 , growth arrest-specific 1 , growth arrest-specific protein 1-like

2619 Homo sapiens
14451 Mus musculus
540336 Bos taurus
607496 Canis lupus familiaris
736324 Pan troglodytes
780149 Xenopus (Silurana) tropicalis
770168 Gallus gallus
683470 Rattus norvegicus
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