Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
Growth arrest-specific 1 plays a role in growth suppression.
Showing 2 out of 2 products:
Studies establish Gas1 as a negative regulator in colorectal cancer.
These results demonstrated that miR (show MLXIP Proteins)-184 and the GAS1/Akt (show AKT1 Proteins) pathway may be a potential therapeutic target for intervertebral disc degeneration.
WT1 (show WT1 Proteins) modulates Akt (show AKT1 Proteins)/JNK (show MAPK8 Proteins) signaling pathway mediated autophagy by controlling the expression of growth arrest-specific 1 (Gas1).
Downregulation of GAS1 is associated with clear cell renal cell carcinoma (show MOK Proteins).
the synergistic effect of Gas1 inhibition and GDNF against glutamate (show GRIN1 Proteins)-induced cell injury in human SH-SY5Y neuroblastoma (show ARHGEF16 Proteins) cells, is reported.
solutions structure and biophysical characterization of the multifaceted signalling effector protein growth arrest specific-1
This review summarizes the structure of Gas1 and molecular mechanism of action during embryonic development and cellular functions.
GAS1 is a novel endogenous inhibitor of glomerular mesangial cell proliferation.
Growth arrest-specific gene 1 is downregulated and inhibits tumor growth in gastric cancer.
GAS1 induced the activity of caspase-3 (show CASP3 Proteins) and resulting in apoptosis of the cells.
Western blot and immunofluorescence analyses showed two GIP (show GIP Proteins)-anchored proteins were clearly involved in the fertilisation process, namely growth arrest specific 1 (Gas1) and glial cell line-derived neurotrophic factor receptor alpha1 (Gfralpha1 (show GFRA1 Proteins)). This was demonstrated by evaluating oocyte fertilisability after treatment of oocytes with antibodies against the selected proteins, with their respective short interference RN...
Findings provide evidence for a dual requirement for Boc (show BOC Proteins) and Gas1 during early development of the palate, mediating cell cycle regulation during growth and subsequent fusion of the palatal shelves.
The results suggest that in diabetes the decrease of Gas1 promotes the activation of parietal progenitor cells of Bowman's capsule that might differentiate into podocytes and compensate their loss observed in this pathology.
Up-regulation of inducible Gas1 contributed to the apoptosis of reactive astrocytes in injured substantia nigra.
The C/EBP (show CEBPA Proteins) target Gas1 is induced in granulosa cells and is associated with ovulation and luteinization.
the overexpression of Gas1 (growth arrest specific 1) gene reduces the size, proliferating activity and malignancy of liver tumors.
WT1 (show WT1 Proteins) modulates receptor tyrosine kinase (show ERBB3 Proteins) signaling in nephron progenitor cell by directing the expression of Gas1.
When Shh (show SHH Proteins) is presented as a point source, enteric axons turn away from it in a Gas1-dependent manner.
widespread distribution and cellular localization of the GAS1 native protein in adult mammalian CNS
finding that Gas1 is transcribed at the G(1)/S transition suggests that the gene may exert a novel function during cell proliferation.
Growth arrest-specific 1 plays a role in growth suppression. GAS1 blocks entry to S phase and prevents cycling of normal and transformed cells. Gas1 is a putative tumor suppressor gene.
, Growth arrest-specific gene-1
, growth arrest-specific protein 1
, growth arrest-specific 1
, growth arrest-specific protein 1-like