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The protein encoded by GAS2L1, a member of the GAS2 family, is similar in sequence to the mouse protein Gas2, an actin-associated protein expressed at high levels in growth-arrested cells.
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This work reveals a GAS2L1-mediated centriole-tethering mechanism of microtubules and actin, which provide the forces required for centrosome dynamics and separation.
GAS2L1 and GAS2L2 are differentially involved in mediating the crosstalk between F-actin and microtubules.
There was no significant difference in the frequency six marker haplotype in the GAS2L1 gene between the cases of schizophreina and controls.
T3-induced genes identified basic transcription element binding protein 1/Kruppel-like factor 9 (show KLF9 Proteins) (BTEB1/KLF9 (show KLF9 Proteins)) and GAR22 as TR target genes
The protein encoded by this gene, a member of the GAS2 family, is similar in sequence to the mouse protein Gas2, an actin-associated protein expressed at high levels in growth-arrested cells. Expression of the mouse Gas2 gene is negatively regulated by serum and growth factors. Three transcript variants encoding two different isoforms have been found for this gene.
GAS2-like protein 1
, GAS2-related protein on chromosome 22
, growth arrest-specific protein 2-like 1
, GAS2-related protein