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Oxidoreductase required for tumor suppression. Additionally we are shipping HIV-1 Tat Interactive Protein 2, 30kDa Antibodies (74) and HIV-1 Tat Interactive Protein 2, 30kDa Proteins (12) and many more products for this protein.
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Human HTATIP2 ELISA Kit for Sandwich ELISA - ABIN578497
Kumtepe, Halici, Sengul, Kunak, Bayir, Kilic, Cadirci, Pulur, Bayraktutan: High serum HTATIP2/TIP30 level in serous ovarian cancer as prognostic or diagnostic marker. in European journal of medical research 2013
These results suggest that TIP30, as a tumor suppressor in the bladder cancer, might be served as a target in cancer therapies in the future.
Binding of HIV1 Tat (show TAT ELISA Kits) to TIP30 enhanced epithelial-to-mesenchymal transition and metastasis by regulating the nuclear translocation of Snail (show SNAI1 ELISA Kits).
Cholangiocarcinoma patients who had high methylation of HTATIP2 and low methylation of UCHL1 (show UCHL1 ELISA Kits) showed longer overall survival than those with low HTATIP2 methylation and high UCHL1 (show UCHL1 ELISA Kits) methylation.
the results suggest that downregulation of TIP30 may result from HBV infection, and subsequently promotes the progression of HCC.
TIP30 expression is associated with a good prognosis in patients with tumors.
these data suggest that positive MCM2 (show MCM2 ELISA Kits) and negative TIP30 expression are closely correlated with the clinical, pathological and biological parameters, in addition to poor prognosis in patients with gallbladder cancer.
The results of the present study indicated that TIP30 may suppress oncogenesis and glioma progression, thereby improving the prognosis of patients with glioma.
combination of sorafenib and metformin inhibits proliferation and invasion in vitro, prolongs median survival, and reduces lung metastasis of HCC in vivo. This effect is closely associated with the upregulation of TIP30
Increased HMGB1 (show HMGB1 ELISA Kits) and cleaved caspase-3 (show CASP3 ELISA Kits) stimulate the proliferation of tumor cells and are correlated with the poor prognosis in colorectal cancer
Data iindicate TIP30 was a marker in predicting the prognosis of esophageal squamous cell carcinoma (ESCC).
Overexpression or knockdown of Htatip2 in hepatocytes affected fatty acid storage and oxidation, consistent with a novel role in mediating the differential effects of PKC isoforms on lipid metabolism.
Data suggest that TIP30 plays a negative regulatory role in oligodendroglial differentiation.
TIP30 is a key regulator for maintaining ER(+) and ER(-)luminal pools in the mammary luminal lineage, and loss of it promotes expansion of ER(+) luminal progenitors and mature cells and ER(+) mammary tumorigenesis.
TIP30 functions as a tumor suppressor to inhibit EGFR (show EGFR ELISA Kits) cytoplasmic and nuclear signaling and suppress adenocarcinogenesis in the lung.
TIP30 complex regulates EGFR (show EGFR ELISA Kits) endocytosis by facilitating the transport of V-ATPases from trans-Golgi network to early endosomes.
Results suggest that Tip30 is an intrinsic and negative regulator of MEC proliferation partly through the inhibition of Wisp2 and Igf-1 expression, and its absence in the mammary gland may predispose MECs to neoplastic transformation.
Oxidoreductase required for tumor suppression. NAPDH- bound form inhibits nuclear import by competing with nuclear import substrates for binding to a subset of nuclear transport receptors. May act as a redox sensor linked to transcription through regulation of nuclear import. Isoform 1 is a metastasis suppressor with proapoptotic as well as antiangiogenic properties. Isoform 2 has an antiapoptotic effect.
HIV-1 Tat interactive protein 2, 30kDa
, HIV-1 tat interactive protein 2, homolog
, oxidoreductase HTATIP2
, tat-interacting protein 30 kDa
, 30 kDa HIV-1 TAT-interacting protein
, HIV-1 TAT-interactive protein 2
, Tat-interacting protein (30kD)
, short chain dehydrogenase/reductase family 44U, member 1
, HIV-1 tat interactive protein 2, 30 kDa homolog