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Involved in meiotic progression (By similarity). Additionally we are shipping HORMAD2 Antibodies (24) and HORMAD2 Kits (6) and many more products for this protein.
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The variant rs2412971, intronic in HORMAD2 at chromosome 22q12.2, was robustly associated with tonsillectomy.
Hormad1 and Hormad2 might not be the susceptible genes for the non-obstructive azoospermia in our study population. However, rs718772 of Hormad2 variant might be associated with testis development in NOA patients.
These findings indicate that polymorphisms at the CT gene HORMAD2 might be involved in the prognosis of advanced non-small-cell lung cancer in Han Chinese.
HORMAD2 is predominantly expressed in human testis and weakly expressed in liver. HORMAD2 is ectopically expressed in nearly 10% of lung cancer samples from Chinese Han individuals.
A HORMAD2-dependent quality control mechanism that recognizes unsynapsis and recruits ATR activity during mammalian meiosis.
these observations strongly suggest that HORMAD2-dependent recruitment of ATR to unsynapsed chromosome axes constitutes a mechanism for the surveillance of asynapsis.
HORMAD1 and HORMAD2 are depleted from synapsed chromosome axes with the help of TRIP13.
Involved in meiotic progression (By similarity).
HORMA domain containing 2
, HORMA domain-containing protein 2