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Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell. Additionally we are shipping Hemagglutinin Proteins (476) and Hemagglutinin Antibodies (332) and many more products for this protein.
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HA present on the surface of VV-infected cells was able to block NKp30 (show NCR3 ELISA Kits)-triggered activation, whereas it stimulated the activation through NKp46 (show NCR1 ELISA Kits), resulting in a decreased NK lysis susceptibility of infected cells.
Deletion of the A56R gene results in varying effects on vaccinia virus virulence.
Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell. Plays a major role in the determination of host range restriction and virulence. Class I viral fusion protein. Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane. Low pH in endosomes induce an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide. Several trimers are required to form a competent fusion pore.