anti-Hematopoietic Prostaglandin D Synthase (HPGDS) Antibodies

Prostaglandin-D synthase is a sigma class glutathione-S-transferase family member. Additionally we are shipping HPGDS Kits (13) and HPGDS Proteins (11) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
HPGDS 27306 O60760
HPGDS 54486 Q9JHF7
HPGDS 58962 O35543
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Top anti-HPGDS Antibodies at antibodies-online.com

Showing 10 out of 22 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB Western blot analysis of HPGDS expression in THP1 (A), Raw264.7 (B), PC12 (C) whole cell lysates. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Rabbit Un-conjugated IHC (p), WB Anti-HPGDS / PGDS antibody IHC staining of human lung. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN958991 concentration 5 ug/ml. 50 μg Log in to see 7 to 9 Days
$727.83
Details
Human Rat Un-conjugated IHC (p), WB Human Thymus (formalin-fixed, paraffin-embedded) stained with PGDS antibody ABIN337149 at 10 ug/ml followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 7 to 9 Days
$639.83
Details
Human Rabbit Un-conjugated ICC, IHC, WB DAB staining on IHC-P;;Samples: Human Stomach cancer Tissue 100 μg Log in to see 13 to 16 Days
$332.00
Details
Mouse Rabbit Un-conjugated ICC, IHC, WB Figure.DAB staining on IHC-P. Samples: Mouse Tissue 100 μg Log in to see 13 to 16 Days
$342.00
Details
Human Rabbit Un-conjugated IHC, IHC (p), WB Western Blot: HPGDS Antibody [NBP1-54625] - Titration: 0.2-1 ug/ml, Positive Control: Human Spleen. Immunohistochemistry-Paraffin: HPGDS Antibody [NBP1-54625] - Human Lung tissue, 5ug/ml. 100 μL Log in to see 8 to 11 Days
$485.88
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p) Immunocytochemistry/Immunofluorescence: HPGDS Antibody [NBP1-83322] Staining of human cell line A-431 shows positivity in nucleus but not nucleoli & cytoplasm. Immunohistochemistry-Paraffin: HPGDS Antibody [NBP1-83322] - Staining of human bone marrow shows moderate cytoplasmic positivity in megakaryocytes. 0.1 mL Log in to see 10 to 13 Days
$491.63
Details
Human Rabbit Un-conjugated IHC, WB   200 μL Log in to see 7 to 9 Days
$903.83
Details
Human Rabbit Un-conjugated WB   100 μL Log in to see 7 to 9 Days
$375.83
Details

HPGDS Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human , ,
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Mouse (Murine)
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Rat (Rattus)


More Antibodies against HPGDS Interaction Partners

Human Hematopoietic Prostaglandin D Synthase (HPGDS) interaction partners

  1. These observations suggest that tumor cell-derived inflammatory cytokines increase L-PGDS (show PTGDS Antibodies) expression and subsequent PGD2 (show PTGDS Antibodies) production in the tumor endothelial cells (ECs). This PGD2 (show PTGDS Antibodies) acts as a negative regulator of the tumorigenic changes in tumor ECs.

  2. we have utilized a broad-scaled affinity proteomics approach to identify three proteins (CCL5 (show CCL5 Antibodies), HPGDS, and NPSR1 (show NPSR1 Antibodies)) with altered plasma levels in asthmatic children compared to healthy controls, representing the first evaluation of HPGDS and NPSR1 (show NPSR1 Antibodies) in plasma.

  3. the development of a competition binding assay amenable to high-throughput screening (HTS (show APCDD1 Antibodies)) in a scintillation proximity assay (SPA (show FASL Antibodies)) format. This assay was used to screen an in-house compound library of approximately 280,000 compounds for novel H-PGDS inhibitors.

  4. Serum levels of beta trace protein and beta 2 microglobulin (show B2M Antibodies) can be used to predict residual kidney function in hemodialysis patients.

  5. BTP and B2M (show B2M Antibodies) levels are less affected than serum by amputation, and should be considered for future study of GFR (show RAPGEF5 Antibodies) estimation

  6. Hematopoietic prostaglandin D synthase defines a proeosinophilic pathogenic effector human T(H)2 cell subpopulation with enhanced function

  7. levels of L-PGDS (show PTGDS Antibodies) in cervicovaginal secretions of pregnant women at different stages of parturition correlate with preterm birth.

  8. PTGDS (show PTGDS Antibodies) mRNA expression was down-regulated in rapid-cycling bipolar disorder patients in a euthymic, depressive, and manic/hypomanic state compared with healthy control subjects.

  9. Expression of MR and prostaglandin D2 synthase (show PTGDS Antibodies) is strongly correlated in adipose tissues from obese patients.

  10. These data indicate that scalp is spatially programmed via mast cell prostaglandin D-synthase (show PTGDS Antibodies) distribution in a manner reminiscent of the pattern seen in androgenetic alopecia.

Mouse (Murine) Hematopoietic Prostaglandin D Synthase (HPGDS) interaction partners

  1. H-PGDS deficiency accelerates the production of SDF-1alpha and the activity of MMP-9 (show MMP9 Antibodies) in the antigen-stimulated intestine. SDF-1alpha receptor blockade or MMP-9 (show MMP9 Antibodies) inhibition relieves the exacerbated mast cell hyperplasia and manifestations observed in H-PGDS(-/-).

  2. HPGDS may play a role in the regulation of inflammation and epithelial cell health within the oviduct.

  3. Data suggest a role for hematopoietic prostaglandin D synthase-produced prostaglandin D(2) in the initial nuclear translocation of SOX9 (show SOX9 Antibodies).

  4. These data suggest that PGD(2) generated via HPGDS has detrimental effects after spinal cord injury and that blocking the activity of this enzyme can be beneficial.

  5. hPGD (show HPGD Antibodies)(2)S-derived cyclopentenone prostaglandins may protect against inflammatory diseases, where T lymphocytes play a pathogenic role, as in rheumatoid arthritis, atopic eczema, and chronic rejection

  6. Our results demonstrated that the neuroprotective effects of HPGDS in our model are mediated by suppression of activation and infiltration of inflammatory cells.

HPGDS Antigen Profile

Protein Summary

The protein encoded by this gene is a glutathione-independent prostaglandin D synthase that catalyzes the conversion of prostaglandin H2 (PGH2) to postaglandin D2 (PGD2). PGD2 functions as a neuromodulator as well as a trophic factor in the central nervous system. PGD2 is also involved in smooth muscle contraction/relaxation and is a potent inhibitor of platelet aggregation. This gene is preferentially expressed in brain. Studies with transgenic mice overexpressing this gene suggest that this gene may be also involved in the regulation of non-rapid eye movement sleep.

Gene names and symbols associated with HPGDS

  • hematopoietic prostaglandin D synthase (HPGDS) antibody
  • prostaglandin D2 synthase (PTGDS) antibody
  • hematopoietic prostaglandin D synthase (hpgds) antibody
  • hematopoietic prostaglandin D synthase (Hpgds) antibody
  • hematopoietic prostaglandin D synthase L homeolog (hpgds.L) antibody
  • gsts antibody
  • GSTS1-1 antibody
  • H-PGDS antibody
  • hpgds antibody
  • hpgds-a antibody
  • hpgds-b antibody
  • hpgdsa antibody
  • L-PGDS antibody
  • LPGDS antibody
  • PDS antibody
  • PGD2 antibody
  • pgds antibody
  • PGDS2 antibody
  • Ptgds2 antibody
  • XlGSTS1 antibody

Protein level used designations for HPGDS

GST class-sigma , glutathione S-transferase sigma , glutathione-dependent PGD synthase , glutathione-dependent PGD synthetase , glutathione-requiring prostaglandin D synthase , hematopoietic prostaglandin D2 synthase , prostaglandin-H2 D-isomerase , PGD2 synthase , beta-trace protein , cerebrin-28 , glutathione-independent PGD synthase , glutathione-independent PGD synthetase , lipocalin-type prostaglandin D synthase , lipocalin-type prostaglandin-D synthase , prostaglandin D synthase , prostaglandin-D2 synthase , prostaglandin D2 synthase, hematopoietic , glutathione S-transferase , prostaglandin D2 synthase 2, hematopoietic , H-PGDS , prostaglandin-D synthase , hematopoietic prostaglandin D synthase , hematopoietic prostaglandin D synthase a , prostaglandin D2 synthase, hematopoietic a

GENE ID SPECIES
27306 Homo sapiens
5730 Homo sapiens
448666 Xenopus (Silurana) tropicalis
54486 Mus musculus
58962 Rattus norvegicus
395863 Gallus gallus
100139892 Bos taurus
398969 Xenopus laevis
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