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HNRPDL belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). Additionally we are shipping HNRPDL Kits (12) and HNRPDL Proteins (7) and many more products for this protein.
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Cow (Bovine) Polyclonal HNRPDL Primary Antibody for WB - ABIN2778938
Li, Johansson, Glahder, Mossberg, Schwartz: Suppression of HPV-16 late L1 5'-splice site SD3632 by binding of hnRNP D proteins and hnRNP A2/B1 to upstream AUAGUA RNA motifs. in Nucleic acids research 2013
Show all 2 Pubmed References
The data of this study show that JKTBP1 and the 14-nt element act independently to mediate NRF internal ribosome entry segment activity.
High HNRNPDL expression is associated with cervical cancer.
Heterogeneous nuclear ribonucleoprotein D-like (HNRPDL) is aberrantly expressed in specimens from colorectal cancer patients.
Both hnRNP D and DL are able to control their own expression by alternative splicing of cassette exons in their 3'UTRs. Exon inclusion produces mRNAs degraded by nonsense-mediated decay. Moreover, hnRNP D and DL control the expression of one another by the same mechanism.
A defect in the RNA-processing protein HNRPDL causes limb-girdle muscular dystrophy 1G.
hnRNP DL and CNBP are novel antigens for SLE patients
A protein encoded by this locus was found to be differentially expressed in postmortem brains from patients with atypical frontotemporal lobar degeneration.
The results indicate that JKTBP1 regulates the level of NRF protein expression by binding to both NRF 5' and 3' UTRs.
Study shows that there is interaction of the intracellular domain of beta-amyloid precursor protein with JKTBP2, indicating that JKTBP2 may have an important function in AD formation.
overexpression of JKTBP1 in LNCaP cells leads to abnormal cell proliferation
This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two RRM domains that bind to RNAs. Three alternatively spliced transcript variants have been described for this gene. One of the variants is probably not translated because the transcript is a candidate for nonsense-mediated mRNA decay. The protein isoforms encoded by this gene are similar to its family member HNRPD.
, hnRPD-like protein
, JKT41-binding protein
, heterogeneous nuclear ribonucleoprotein D-like-A
, hnRNP D-like A
, hnRNP DL-A
, hnRPD-like protein A
, A+U-rich element RNA binding factor
, AU-rich element RNA-binding factor
, hnRNP DL
, protein laAUF1
, heterogeneous nuclear ribonucleoprotein D-like
, heterogeneous nuclear ribonucleoprotein D-like-B
, hnRNP D-like B
, hnRNP DL-B
, hnRPD-like protein B