anti-Hook Homolog 1 (Drosophila) (HOOK1) Antibodies

HOOK1 encodes a member of the hook family of coiled-coil proteins, which bind to microtubules and organelles through their N- and C-terminal domains, respectively. Additionally we are shipping Hook Homolog 1 (Drosophila) Proteins (5) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
HOOK1 77963 Q8BIL5
HOOK1 313370  
HOOK1 51361 Q9UJC3
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Top anti-Hook Homolog 1 (Drosophila) Antibodies at antibodies-online.com

Showing 10 out of 64 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Cow Rabbit Un-conjugated WB 100 μL 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IP, WB HOOK1 MaxPab rabbit polyclonal antibody. Western Blot analysis of HOOK1 expression in mouse testis. HOOK1 MaxPab rabbit polyclonal antibody. Western Blot analysis of HOOK1 expression in human pancreas. 100 μL 11 to 12 Days
$425.71
Details
Guinea Pig Rabbit Un-conjugated WB 100 μL 11 to 14 Days
$551.83
Details
Human Mouse Un-conjugated ELISA, IHC, IHC (p), WB 100 μg 11 to 14 Days
$551.83
Details
Human Mouse Un-conjugated IHC (p), ELISA, WB HOOK1 monoclonal antibody (M02), clone 1D11. Western Blot analysis of HOOK1 expression in MCF-7 Immunoperoxidase of monoclonal antibody to HOOK1 on formalin-fixed paraffin-embedded human small Intestine. [antibody concentration 3 ug/ml] 100 μg 11 to 12 Days
$440.00
Details
Human Rabbit Un-conjugated WB Western blot analysis in WiDr cell line lysates (35ug/lane). 400 μL 2 to 3 Days
$515.63
Details
Human Rabbit Un-conjugated IHC, WB Western blot analysis of extracts of various cells, using HOOK1 antibody. 100 μL 11 to 13 Days
$366.77
Details
Human Mouse Un-conjugated WB Western Blot analysis of HOOK1 expression in transfected 293T cell line by HOOK1 MaxPab polyclonal antibody.Lane 1: HOOK1 transfected lysate(80.08 KDa).Lane 2: Non-transfected lysate. HOOK1 MaxPab polyclonal antibody. Western Blot analysis of HOOK1 expression in 293. 50 μL 11 to 12 Days
$440.00
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Mouse Large intestine lysates probed with HOOK1 Polyclonal Antibody, Unconjugated  at 1:300 dilution and 4˚C overnight incubation. Followed by conjugated secondary antibody incubation at 1:10000 for 60 min at 37˚C. 100 μL 14 to 21 Days
$329.45
Details
Human Rabbit Un-conjugated WB Western blot analysis of extracts of various cell lines, using HOOK1 antibody (ABIN5972717) at 1/1000 dilution. 100 μL 11 to 16 Days
$426.40
Details

Top referenced anti-Hook Homolog 1 (Drosophila) Antibodies

  1. Human Polyclonal HOOK1 Primary Antibody for IHC, IHC (p) - ABIN4319664 : Cadalbert, Ghaffar, Stevenson, Bryson, Vaz, Gottlieb, Strathdee: Mouse Tafazzin Is Required for Male Germ Cell Meiosis and Spermatogenesis. in PLoS ONE 2015 (PubMed)

More Antibodies against Hook Homolog 1 (Drosophila) Interaction Partners

Mouse (Murine) Hook Homolog 1 (Drosophila) (HOOK1) interaction partners

  1. Hook1 is a binding partner of Ccdc181.

  2. Single-molecule motility assays using total internal reflection fluorescence microscopy indicate that both Hook1 and Hook3 effectively activate cytoplasmic dynein, inducing longer run lengths and higher velocities than the previously characterized dynein activator bicaudal D2 (BICD2).

  3. azh mutation is due to a deletion of exons 10 and 11 in the murine Hook1 gene leading to a non-functional protein. Our results indicate that loss of Hook1 function results in ectopic positioning of microtubular structures within the spermatid

  4. Hook1 and Ankyrin G are co-locolized, Hook1 also localizes to additional regions of the cell devoid of Ankyrin G where it interacts with other proteins.

  5. Multiple samples of ejaculated spermatozoa from normal fertile C57BL/6 and infertile Hook1/Hook1 (formerly known as azh/azh) mutant males from uteri after mating.

Human Hook Homolog 1 (Drosophila) (HOOK1) interaction partners

  1. unreported mutation in HOOK1 gene was identified, which might be responsible to some patients with decapitated and decaudated spermatozoa (DDS) syndrome. Further studies need to uncover the molecular mechanism of spermiogenesis for genomic therapy.

  2. Hook1 knockdown promoted epithelial-mesenchymal transition and attenuated the sensitivity of hepatocellular carcinoma cells to doxorubicin. In summary, our results indicate that downregulation of Hook1 plays a pivotal role in hepatocellular carcinoma progression via epithelial-mesenchymal transition. Hook1 may be used as a novel marker and therapeutic molecular target in hepatocellular carcinoma

  3. Single-molecule motility assays using total internal reflection fluorescence microscopy indicate that both Hook1 and Hook3 effectively activate cytoplasmic dynein, inducing longer run lengths and higher velocities than the previously characterized dynein activator bicaudal D2 (BICD2).

  4. SHP2 positively regulates TGFbeta1-induced epithelial-mesenchymal transition modulated by its novel interacting protein Hook1.

  5. Hook1, a microtubule- and cargo-tethering protein, recognized the cytoplasmic tail of CD147 to help sort it and CD98 into Rab22a-dependent tubules associated with recycling.

  6. novel interactions between the microtubule-binding Hook1 and the large family of Rab GTPases also suggest a link between CLN3 function, microtubule cytoskeleton and endocytic membrane trafficking

  7. These data suggest that the FTS/Hook/FHIP complex functions to promote vesicle trafficking and/or fusion via the homotypic vacuolar protein sorting complex.

Hook Homolog 1 (Drosophila) (HOOK1) Antigen Profile

Protein Summary

This gene encodes a member of the hook family of coiled-coil proteins, which bind to microtubules and organelles through their N- and C-terminal domains, respectively. The encoded protein localizes to discrete punctuate subcellular structures, and interacts with several members of the Rab GTPase family involved in endocytosis. It is thought to link endocytic membrane trafficking to the microtubule cytoskeleton. Several alternatively spliced transcript variants have been identified, but the full-length nature of some of these variants has not been determined.

Gene names and symbols associated with HOOK1

  • hook microtubule tethering protein 1 (HOOK1) antibody
  • hook microtubule-tethering protein 1 (hook1) antibody
  • hook microtubule tethering protein 1 (Hook1) antibody
  • hook microtubule-tethering protein 1 (Hook1) antibody
  • A930033L17Rik antibody
  • azh antibody
  • HK1 antibody
  • HOOK1 antibody
  • si:dkey-183n20.14 antibody

Protein level used designations for HOOK1

hook homolog 1 (Drosophila) , protein Hook homolog 1 , abnormal spermatozoon head shape , mHK1 , h-hook1 , hHK1 , hook homolog 1

GENE ID SPECIES
456895 Pan troglodytes
570393 Danio rerio
77963 Mus musculus
424675 Gallus gallus
479553 Canis lupus familiaris
100525467 Sus scrofa
313370 Rattus norvegicus
51361 Homo sapiens
785042 Bos taurus
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