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The protein encoded by IK was identified by its RED repeat, a stretch of repeated arginine, glutamic acid and aspartic acid residues. Additionally we are shipping IK Cytokine, Down-Regulator of HLA II Antibodies (14) and IK Cytokine, Down-Regulator of HLA II Kits (6) and many more products for this protein.
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Taken together, these results imply that IK plays a role in downregulating MHC class II expression on B cells during coxsackievirus B3 infection through the induction of cAMP.
IK inhibits Aurora B (show AURKB Proteins) activation through recruiting PP2A (show PPP2R4 Proteins) into IK and Aurora B (show AURKB Proteins) complex.
Data suggest that two human spliceosomal factors, RED and SMU1, are recruited to control expression and alternative splicing of viral exportins via PB2 (polymerase PB2) of influenza A virus (H3N2) and are required for efficient viral multiplication.
RED is required for kinetochore localization of MAD1 (show MXD1 Proteins), mitotic progression, and activation of the spindle assembly checkpoint.
At least three genes, orthologous to loci in this LD block, HBEGF (show HBEGF Proteins), IK, and SRA1 (show SRA1 Proteins), result independently in a phenotype of myocardial contractile dysfunction when their expression is reduced with morpholino antisense reagents.
The protein encoded by this gene was identified by its RED repeat, a stretch of repeated arginine, glutamic acid and aspartic acid residues. The protein localizes to discrete dots within the nucleus, excluding the nucleolus. Its function is unknown. This gene maps to chromosome 5\; however, a pseudogene may exist on chromosome 2.
IK cytokine, down-regulator of HLA II
, protein Red
, protein Red-like
, IK factor
, arginine/glutamic acid/aspartic acid repeat containing protein
, cytokine IK
, Ik factor
, chondrosarcoma-associated protein 2
, RD element
, prer protein
, RED protein