anti-ITGAV/ITGB3 (ITGAV/ITGB3) Antibodies

ITAGV encodes integrin alpha chain V. Additionally we are shipping ITGAV/ITGB3 Proteins (3) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ITGAV/ITGB3 3685 P06756
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Top anti-ITGAV/ITGB3 Antibodies at

Showing 10 out of 73 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated FACS, IF (p), IHC (p) Formalin-fixed and paraffin embedded rat brain labeled with Rabbit Anti Integrin Alpha V + Beta 3 (CD51+CD61) Polyclonal Antibody, Unconjugated (ABIN674784) at 1:200 followed by conjugation to the secondary antibody and DAB staining MCF-7 cells probed with Rabbit Anti-Integrin Alpha V + Beta 3 (CD51+CD61) Polyclonal Antibody  Alexa Fluor 488 Conjugated Secondary Antibody. 100 μL Log in to see 14 to 21 Days
Human Mouse Un-conjugated BR, CyTOF, FACS, IHC, IP   100 μg Log in to see 8 to 9 Days
Human Mouse PE FACS 100 Tests Log in to see 8 to 9 Days
Human Mouse Un-conjugated FACS 50 μg Log in to see 10 to 12 Days
Human Mouse Biotin FACS, IP, IHC, WB 100 μg Log in to see 10 to 12 Days
Human Mouse FITC FACS 100 Tests Log in to see 10 to 12 Days
Human Mouse Alexa Fluor 647 ELISA (Capture), IP, Neut, WB 100 Tests Log in to see 10 to 12 Days
Human Mouse Alexa Fluor 488 FACS 100 Tests Log in to see 10 to 12 Days
Human Mouse APC FACS Detection of Integrin alpha V beta 3 in HUVEC Human Cells by Flow Cytometry. HUVEC human umbilical vein endothelial cells were stained with Mouse Anti-Human Integrin alpha V beta 3 APC-conjugated Monoclonal Antibody. 100 Tests Log in to see 8 to 9 Days
Chicken Mouse Un-conjugated IHC (fro), FACS, IP   0.1 mg Log in to see 3 to 4 Days

Top referenced anti-ITGAV/ITGB3 Antibodies

  1. Human Monoclonal ITGAV/ITGB3 Primary Antibody for BR, CyTOF - ABIN5012934 : Suri, Rakotondradany, Myles, Fenniri, Singh: The role of RGD-tagged helical rosette nanotubes in the induction of inflammation and apoptosis in human lung adenocarcinoma cells through the P38 MAPK pathway. in Biomaterials 2009 (PubMed)
    Show all 11 Pubmed References

  2. Human Polyclonal ITGAV/ITGB3 Primary Antibody for FACS, IF (p) - ABIN674784 : Mondal, Barui, Chaudhuri: The relationship between the cyclic-RGDfK ligand and ?v?3 integrin receptor. in Biomaterials 2013 (PubMed)
    Show all 7 Pubmed References

  3. Human Monoclonal ITGAV/ITGB3 Primary Antibody for FACS - ABIN1177347 : Chuntharapai, Bodary, Horton, Kim: Blocking monoclonal antibodies to alpha V beta 3 integrin: a unique epitope of alpha V beta 3 integrin is present on human osteoclasts. in Experimental cell research 1993 (PubMed)
    Show all 5 Pubmed References

  4. Human Monoclonal ITGAV/ITGB3 Primary Antibody for FACS - ABIN4898649 : Chang, Lo, Juan, Chang, Chuang: Combination of RGD compound and low-dose paclitaxel induces apoptosis in human glioblastoma cells. in PLoS ONE 2012 (PubMed)
    Show all 4 Pubmed References

  5. Human Monoclonal ITGAV/ITGB3 Primary Antibody for FACS, IHC - ABIN2191902 : Newton, Girgenti, Collier, Duman: Electroconvulsive seizure increases adult hippocampal angiogenesis in rats. in The European journal of neuroscience 2006 (PubMed)
    Show all 3 Pubmed References

  6. Human Monoclonal ITGAV/ITGB3 Primary Antibody for FACS, IHC - ABIN2191903 : Merkel, Germershaus, Wada, Tarcha, Merdan, Kissel: Integrin alphaVbeta3 targeted gene delivery using RGD peptidomimetic conjugates with copolymers of PEGylated poly(ethylene imine). in Bioconjugate chemistry 2009 (PubMed)
    Show all 3 Pubmed References

  7. Human Monoclonal ITGAV/ITGB3 Primary Antibody for FACS - ABIN2689327 : Nesbitt, Nesbit, Helfrich, Horton: Biochemical characterization of human osteoclast integrins. Osteoclasts express alpha v beta 3, alpha 2 beta 1, and alpha v beta 1 integrins. in The Journal of biological chemistry 1993 (PubMed)

  8. Human Monoclonal ITGAV/ITGB3 Primary Antibody for CyTOF, FACS - ABIN4961570 : Sha, Zou, Xin, Bian, Cai, Lu, Chen, Chen, Huang, Blair, Cao, Liu: Tumor-penetrating peptide fused EGFR single-domain antibody enhances cancer drug penetration into 3D multicellular spheroids and facilitates effective gastric cancer therapy. in Journal of controlled release : official journal of the Controlled Release Society 2015 (PubMed)

  9. Chicken Monoclonal ITGAV/ITGB3 Primary Antibody for IHC (fro), FACS - ABIN2480901 : Simpson, Horton: Expression of the vitronectin receptor during embryonic development; an immunohistological study of the ontogeny of the osteoclast in the rabbit. in British journal of experimental pathology 1989 (PubMed)
    Show all 4 Pubmed References

More Antibodies against ITGAV/ITGB3 Interaction Partners

Human ITGAV/ITGB3 interaction partners

  1. ITGAV and ITGA5 diversely regulate proliferation and adipogenic differentiation of human adipose derived stem cells.

  2. SAA1 in combination with integrin alphaV and beta3 can serve as an indicator of high glioblastoma risk.

  3. Findings indicated that IL-32gamma suppressed skin carcinogenesis through the inhibition of both stemness and the inflammatory tumor microenvironment by the downregulation of TIMP-1 and ITGAV via inactivation of NF-kappaB signaling.

  4. This study provides evidence that germline polymorphisms in VEGFR1, KRAS and ITGAV genes are associated with prognosis in stages II-III colon cancer patients. As stage and tumor location are correlated with prognosis, future genetic studies should stratify colon cancer patients according to these parameters.

  5. Binding of small molecule ligands and radiolabelled RGD peptides is modulated by expression and activation status of alphavbeta3 integrin.

  6. There is no difference in the expression of Integrin alphavbeta3 between tumor samples from glioblastomas patients with methylated or unmethylated promoter regions in the (6)O-methylguanine methyltransferase (MGMT). Further analysis of the integrin subunits via ELISA from histologic sections revealed that there is no difference in integrin subunit expression between these patients.

  7. These data suggested CD51 was a predictor for the prognosis of esophageal squamous cell carcinoma patients

  8. This study shows that the D2A sequence of the UPAR induces cell growth through alphaVbeta3 integrin and EGFR.

  9. Cyclin D1b markedly amplified integrin alphavbeta3 expression, which was further up-regulated under lipopolysaccharide stimulation.

  10. differential expression of alphavbeta3 and alphavbeta6 was examined in MDA-MB-231, MDA-MB-468 and MCF-10A cells, which signify three different stages of breast cancer development from highly metastatic to non-tumorigenic stage.

  11. High expression of Integrin alphaVbeta6 is an important cause of active proliferation and impaired apoptosis in cervical cancer.

  12. The results of the present study suggest that the traditional Chinese formula WD3 may inhibit gastric tumor growth, potentially via the downregulation of integrin alphav beta3 and the inhibition of ERK1/2 phosphorylation in vivo

  13. of AIM-cleavage and resulting functional modification could be the basis for designing safe and efficient AIM therapy for various diseases

  14. show that sCD40L/alpha5beta1 interaction leads to platelet activation as evaluated in the human whole blood

  15. Among Greek and Polish patients with intracerebral hemorrhage, the rs7565633 tag SNP of the ITGAV gene was independently associated with the risk of lobar ICH in a codominant model of inheritance.

  16. Although Mn(2+) potently activates other integrins and increases affinity of alphaVbeta6 for pro-TGF-beta1 25- to 55-fold, it increases alphaVbeta8 affinity only 2- to 3-fold.

  17. This work identifies that therapeutic targeting of integrins containing an alpha V integrin unit inhibits cancer progression and thus may be of clinical benefit.

  18. this study uncovers a novel pathway by which the TGFbeta-activating integrin alphavbeta8 is expressed in the human intestine on dendritic cell subsets, which is upregulated in patients with inflammatory bowel disease

  19. Integrin alphavbeta3 has a role in enhancing beta-catenin signaling in acute myeloid leukemia harboring Fms-like tyrosine kinase-3 internal tandem duplication mutations

  20. BKCa has a role in promoting growth and metastasis of prostate cancer through facilitating the coupling between alphavbeta3 integrin and FAK

Cow (Bovine) ITGAV/ITGB3 interaction partners

  1. identified as receptor for foot-and-mouth disease virus

  2. Flow induced alpha2beta1 activation in cells on collagen, but not on fibronectin or fibrinogen. Conversely, alpha5beta1 and alphavbeta3 are activated on fibronectin and fibrinogen, but not collagen.

  3. specific substitutions show that the stable binding between foot-and-mouth disease virus VP1 and integrin alphavbeta6 is dependent on a helical structure and, specifically, two leucine residues at positions +1 and RGD +4 from the RGD motif.

  4. These results demonstrate the critical role of the RhoA/alphavbeta5 integrin pathway in mediating Pseudomonas aeruginosa-induced lung vascular permeability.

Pig (Porcine) ITGAV/ITGB3 interaction partners

  1. Blocking ligand binding to the alphaVbeta3 integrin inhibits its activation and prevents coronary artery atherosclerosis in diabetic pigs.

  2. The observed effects of shear stress on integrin alpha(v)beta(3) and p38 MAPK activation, as well as on FGF-2 release could be mimicked by application of pancreatic elastase to static endothelial cells.

  3. Data show that integrin alphav, beta3, beta6 and beta8 subunit shares common structural and functional elements.

  4. The strong expression of integrin alphaV and beta3 in mid-implantation may indicate its crucial role in successful implantation and embryo survival.

  5. signaling events following ligand binding to alphaVbeta3 integrin reflect a balance between the effects mediated through the RGD binding site interaction and the effects mediated by the heparin binding site interaction

  6. Inhibition of integrin alphavbeta3 prevents urokinase plasminogen activator-mediated impairment of cerebrovasodilation after cerebral hypoxia/ischemia.

ITGAV/ITGB3 Antigen Profile

Protein Summary

ITAGV encodes integrin alpha chain V. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The I-domain containing integrin alpha V undergoes post-translational cleavage to yield disulfide-linked heavy and light chains, that combine with multiple integrin beta chains to form different integrins. Among the known associating beta chains (beta chains 1,3,5,6, and 8\; 'ITGB1', 'ITGB3', 'ITGB5', 'ITGB6', and 'ITGB8'), each can interact with extracellular matrix ligands\; the alpha V beta 3 integrin, perhaps the most studied of these, is referred to as the Vitronectin receptor (VNR). In addition to adhesion, many integrins are known to facilitate signal transduction. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with ITGAV/ITGB3

  • integrin subunit alpha V (ITGAV) antibody
  • CD51 antibody
  • MSK8 antibody
  • VNRA antibody
  • VTNR antibody

Protein level used designations for ITGAV/ITGB3

antigen identified by monoclonal antibody L230 , integrin alpha-V , integrin alphaVbeta3 , integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51) , vitronectin receptor subunit alpha , vitronectin receptor alpha subunit , integrin alpha V subunit , alphaV integrin , integrin alpha v

3685 Homo sapiens
396420 Gallus gallus
488437 Canis lupus familiaris
281875 Bos taurus
397285 Sus scrofa
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