Immune Receptor Expressed On Myeloid Cells 1 (IREM1) ELISA Kits

CD300LF is an inhibitory receptor of the Ig superfamily expressed on myeloid cells. Additionally we are shipping Immune Receptor Expressed On Myeloid Cells 1 Antibodies (65) and Immune Receptor Expressed On Myeloid Cells 1 Proteins (12) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
IREM1 246746 Q6SJQ7
IREM1 287818 Q566E6
IREM1 146722 Q8TDQ1
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Top Immune Receptor Expressed On Myeloid Cells 1 ELISA Kits at antibodies-online.com

Showing 6 out of 15 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Delivery Price Details
Human 0.059 ng/mL 0.15 ng/mL - 10 ng/mL 96 Tests 13 to 16 Days
$700.00
Details
Mouse 0.62 ng/mL 1.56 ng/mL - 100 ng/mL 96 Tests 13 to 16 Days
$720.00
Details
Human
  96 Tests 26 to 36 Days
$899.80
Details
Rat < 0.094 ng/mL 0.156 ng/mL - 10 ng/mL   96 Tests 11 to 18 Days
$838.60
Details
Human < 0.059 ng/mL 0.156 ng/mL - 10 ng/mL   96 Tests 11 to 18 Days
$902.56
Details
Mouse < 0.62 ng/mL 1.56 ng/mL - 100 ng/mL   96 Tests 11 to 18 Days
$966.52
Details

Top referenced Immune Receptor Expressed On Myeloid Cells 1 ELISA Kits

  1. Mouse (Murine) IREM1 ELISA Kit for Sandwich ELISA - ABIN424793 : Ejarque-Ortiz, Solà, Martínez-Barriocanal, Schwartz, Martín, Peluffo, Sayós: The Receptor CMRF35-Like Molecule-1 (CLM-1) Enhances the Production of LPS-Induced Pro-Inflammatory Mediators during Microglial Activation. in PLoS ONE 2015 (PubMed)

More ELISA Kits for Immune Receptor Expressed On Myeloid Cells 1 Interaction Partners

Mouse (Murine) Immune Receptor Expressed On Myeloid Cells 1 (IREM1) interaction partners

  1. Although the serine palmitoyltransferase complex is dispensable for the surface expression of the norovirus receptor (CD300lf), enzyme activity is required for CD300lf to adopt a conformation permissive for viral binding. Addition of extracellular ceramide to serine palmitoyltransferase-deficient cells complements both the conformational changes of CD300lf and the cellular susceptibility to murine norovirus infection.

  2. the ceramide-CD300f interaction inhibits neutrophil recruitment to the sites of Gram-negative bacterial skin infections in mice.

  3. These findings highlight the cross-talk between IL-5 receptor and CD300f as a novel pathway regulating adipose tissue eosinophils.

  4. Docking of the cocomplex structures onto a cryo-EM-derived model of MNoV suggests that each virion can make multiple CD300lf engagements, and thus, infection may be driven by the avidity of cell surface clustered CD300lf.

  5. sCD300lf bound on the mouse norovirus P domain. The receptor-binding site was located on the topside of the P2 subdomain and involved hydrophilic and hydrophobic interactions. The sCD300lf bound in a small cavity and was further supported by a positive surface charge on the sCD300lf and negative surface charge on the P domain.

  6. Our results indicate that direct interaction of MNV with two cell-surface molecules, CD300lf and CD300ld, dictates permissive noroviral infection.

  7. CD300f helps to maintain immune homeostasis by promoting macrophage clearance of self-antigens, while conversely inhibiting DC uptake and presentation of self-antigens.

  8. dextran sodium sulfate-treated Cd300f-/- mice exhibit attenuated disease activity and histopathology in comparison with wild type controls

  9. data highlight a previously unappreciated role for dendritic cells in controlling gut homeostasis and show that CD300f-dependent regulation of apoptotic cell uptake is essential for suppressing overactive dendritic cell-mediated inflammatory responses, thereby controlling the development of chronic gut inflammation.

  10. ceramide-CD300f binding inhibits LPS-induced skin inflammation, implicating CD300f as a negative regulator of Toll-like receptor 4 (TLR4) signaling in vivo

  11. CD300lf is essential for murine noroviruse binding and replication in cell lines and primary cells.

  12. CD300f is implicated in Wallerian degeneration and nerve regeneration by modulating both the influx and phenotype of macrophages

  13. Y276 phosphorylation is necessary for enhanced CD300f-mediated phagocytosis through the recruitment of the p85alpha regulatory subunit of phosphatidylinositol-3-kinase

  14. data highlight a previously unidentified role for CD300f in IL-4Ralpha-induced immune cell responses

  15. CMRF35-like molecule 1 (CLM-1) regulates eosinophil homeostasis by suppressing cellular chemotaxis.

  16. Several extracellular lipids (including ceramide) and lipoproteins were possible ligands for LMIR3.

  17. We conclude that expression of CD300f conveys additional capacity to recognize phosphatidylserine to myeloid cells.

  18. CLM-1 as a negative regulator of myeloid effector cells in autoimmune demyelination.

  19. DIgR2 is a functionally inhibitory receptor and can mediate negative signaling to regulate DC-initiated antigen-specific T-cell responses.

  20. the innate immune system is at least in part regulated by the qualitative and quantitative balance of the paired receptors LMIR3 and LMIR4

Human Immune Receptor Expressed On Myeloid Cells 1 (IREM1) interaction partners

  1. ceramide-CD300f interaction inhibits neutrophil recruitment to the sites of Gram-negative bacterial skin infections in mice.

  2. this study demonstrates the role of CD300f in governing innate immune eosinophil activities in pediatric Crohn's disease patients and in active ulcerative colitis patients

  3. findings suggest that two rare heterozygous truncating variations (RPS24 Q191X and CD300LF P261fsX266) are risk candidates for autism spectrum disorder.

  4. CD300 molecules are all expressed by DC; CD300b, d, e and f are restricted to different subpopulations of the myeloid DC lineage. They have been shown to regulate DC function both in vitro and in vivo.

  5. The data suggest that the neuroprotective role of CD300f would be the result of a complex network of cell interactions.

  6. peptides containing ITIM-like sequences of IREM-1 (CD300F) differentially regulate MyD88 and TRIF-mediated TLR signalling

  7. CD300f blocked the activation of cells induced by all TLR ligands

  8. Data indicate that CD300F is an active regulator of TLR-mediated macrophage activation through association with SHP-1 involving MyD88 and/or TRIF.

  9. Findings indicate that IREM-1 exerted its inhibitory effect on BAFF-medicated signalling through ITIM-mediated regulation of ERK activities in THP-1 cells.

  10. IgSF13 was identified from dendritic cells; preferentially expressed in myelo-monocytic cells, including monocytes, monocyte-derived DC and monocyte-related cell lines; may be involved in the negative regulation of specific leukocyte population [IgSF13]

  11. a novel inhibitory receptor of the Ig superfamily in myeloid cells. (IREM-1 = immune receptor expressed on myeloid cells-1)

  12. reveal a putative functional duality of the IREM-1 myeloid cell receptor

Immune Receptor Expressed On Myeloid Cells 1 (IREM1) Antigen Profile

Antigen Summary

CD300LF is an inhibitory receptor of the Ig superfamily expressed on myeloid cells. It mediates negative regulatory signals by recruiting SHP1 (PTPN6\; MIM 176883) or SHIP (INPP5D\; MIM 601582) (Sui et al., 2004

Gene names and symbols associated with IREM1

  • CD300 molecule like family member F (Cd300lf) antibody
  • Cd300 molecule-like family member F (Cd300lf) antibody
  • CD300 molecule like family member f (CD300LF) antibody
  • CD300f antibody
  • CLIM1 antibody
  • CLM-1 antibody
  • CLM1 antibody
  • Digr2 antibody
  • F730004D16Rik antibody
  • IgSF13 antibody
  • IREM-1 antibody
  • IREM1 antibody
  • LMIR3 antibody
  • NKIR antibody
  • Pigr3 antibody
  • RGD1309733 antibody

Protein level used designations for IREM1

CD300 antigen-like family member F , CMRF-35-like molecule 1 , CMRF35-like molecule 1 , DC-derived Ig-like receptor 2 , MAIR-5 , MAIR-V , leukocyte mono-Ig-like receptor 3 , myeloid-associated immunoglobulin-like receptor 5 , CD300 antigen like family member F , CLM-1 , CD300 molecule like family member f , NK inhibitory receptor , immune receptor expressed on myeloid cells 1 , immunoglobin superfamily member 13 , immunoglobulin superfamily member 13 , inhibitory receptor IREM1

GENE ID SPECIES
246746 Mus musculus
287818 Rattus norvegicus
146722 Homo sapiens
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