anti-Insulin-Like Growth Factor 2 MRNA Binding Protein 1 (IGF2BP1) Antibodies

IGF2BP1 encodes a member of the insulin-like growth factor 2 mRNA-binding protein family. Additionally we are shipping IGF2BP1 Proteins (5) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
IGF2BP1 10642 Q9NZI8
IGF2BP1 140486 O88477
IGF2BP1 303477 Q8CGX0
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Top anti-IGF2BP1 Antibodies at antibodies-online.com

Showing 10 out of 76 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated IHC, WB WB Suggested Anti-IGF2BP1 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:12500  Positive Control:  HepG2 cell lysate Host:  Rabbit  Target Name:  IGF2BP1  Sample Tissue:  Rat Skeletal Muscle  Antibody Dilution:  1ug/ml 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated IHC, WB WB Suggested Anti-IGF2BP1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Jurkat cell lysate 100 μL Log in to see 2 to 3 Days
$319.00
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB IGF2BP1 Antibody (C-term) (ABIN654423) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. Overlay histogram showing HepG2 cells stained with ABIN2844158(green line). The cells were fixed with 2% paraformaldehyde (10 min) and then permeabilized with 90% methanol for 10 min. The cells were then icubated in 2% bovine serum albumin to block non-specific protein-protein interactions followed by the antibody (ABIN2844158, 1:25 dilution) for 60 min at 37ºC. The secondary antibody used was Goat-Anti-Rabbit IgG, DyLight® 488 Conjugated Highly Cross-Adsorbed(OE188374) at 1/200 dilution for 40 min at 37ºC. Isotype control antibody (blue line) was rabbit IgG1 (1μg/1x10^6 cells) used under the same conditions. Acquisition of >10, 000 events was performed. Dilution: 1:25 400 μL Log in to see 10 to 11 Days
$385.00
Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Goat Un-conjugated ELISA, IHC, WB ABIN571172 (0.3µg/ml) staining of K562 lysate (35µg protein in RIPA buffer). Detected by chemiluminescence. 100 μg Log in to see 6 to 7 Days
$429.84
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), WB Immunocytochemistry/Immunofluorescence: IGF2BP1 Antibody [NBP1-83108] - Staining of human cell line A-431 shows positivity in nucleus but not nucleoli, plasma membrane, cytoplasm & vesicles. Western Blot: IGF2BP1 Antibody [NBP1-83108] - Lane 1: NIH-3T3 cell lysate (Mouse embryonic fibroblast cells).Lane 2: NBT-II cell lysate (Rat Wistar bladder tumour cells) 0.1 mL Log in to see 34 Days
$494.38
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB IGF2BP1 Antibody (C-term) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. IGF2BP1 antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human prostate carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the IGF2BP1 antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated. 0.4 mL Log in to see 6 to 8 Days
$484.00
Details
Human Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$515.63
Details
Cow Goat Un-conjugated ELISA, IHC, IHC (p), WB 50 μg Log in to see 11 to 14 Days
$484.00
Details
Dog Rabbit Un-conjugated IHC, IHC (p), WB Human Kidney (formalin-fixed, paraffin-embedded) stained with IGF2BP1 antibody ABIN214118 at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. Anti-IGF2BP1 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. This image was taken for the unconjugated form of this product. Other f ... 50 μg Log in to see 11 to 14 Days
$727.83
Details

Top referenced anti-IGF2BP1 Antibodies

  1. Human Polyclonal IGF2BP1 Primary Antibody for FACS, IHC (p) - ABIN654423 : Zhou, Rong, Zhang, Aloysius, Pan, Liang: Insulin-like growth factor II mRNA binding protein 1 modulates Rev-dependent human immunodeficiency virus type 1 RNA expression. in Virology 2009 (PubMed)
    Show all 4 Pubmed References

  2. Human Polyclonal IGF2BP1 Primary Antibody for ELISA, WB - ABIN4321629 : Noubissi, Goswami, Sanek, Kawakami, Minamoto, Moser, Grinblat, Spiegelman: Wnt signaling stimulates transcriptional outcome of the Hedgehog pathway by stabilizing GLI1 mRNA. in Cancer research 2009 (PubMed)

More Antibodies against IGF2BP1 Interaction Partners

Human Insulin-Like Growth Factor 2 MRNA Binding Protein 1 (IGF2BP1) interaction partners

  1. IMP1 shows alternating binding in nanocores and anomalous diffusion in the liquid phase of stress granules.

  2. Results demonstrate that IGF2BP1 plays an important role in the sensitivity of melanoma to targeted therapy. Inhibition of IGF2BP1 enhances the effects of BRAF-inhibitor and BRAF-MEK inhibitors in BRAF(V600E) melanoma. Also, knockdown of IGF2BP1 alone is sufficient to reduce tumorigenic characteristics in vemurafenib-resistant melanoma.

  3. lncRNA THOR is up-regulated in retinoblastoma, and its over-expression significantly enhances the malignant phenotype transformation of retinoblastoma cells by up-regulating c-myc and TGF2BP1 expression.

  4. SOX12 can increase the expression of CDK4 and IGF2BP1, which confer malignant phenotypes to Hepatocellular Carcinoma.

  5. report insulin-like growth factor-II binding protein 1 (IGF2BP1) as a novel interacting partner of p38 MAPK.

  6. IGF2BP1 mediates posttranscriptional loss of BCL11A in cultured human adult erythroblasts

  7. HCG11 exerted its effect on Hepatocellular carcinoma (HCC)via interaction with IGF2BP1, leading to activation of MAPK signaling, which eventually promoted the progression of HCC

  8. miR-98-5p, downregulated in HCC, inhibits proliferation while inducing apoptosis in HCC LM3 cells, partly at least, through directly targeting IGF2BP1

  9. Findings suggest a MicroRNA-140-5p (miR-140-5p)-Insulin like growth factor 2 mRNA binding protein 1 (IGF2BP1) regulatory circuit for CC pathogenesis, and miR-140-5p may be a potential target for CC therapy.

  10. Our studies provide insights into a molecular mechanism that the positive function of IMP1 to inhibit breast tumor growth and metastasis

  11. The regions encoding 71 microRNAs (miRs) were deleted in at least 25% of tumor specimens. Five of these recurrently deleted miRs targeted the insulin-like growth factor 2 mRNA-binding protein 1 (IGF2BP1) gene product, and a correlating 100-fold upregulation of IGF2BP1 mRNA was seen in tumor specimens

  12. Insight into molecular interactions between CRD-BP and MITF mRNA.

  13. IGF2BP1 indirectly potentiates ETV6/RUNX1-RAC1-STAT3 signaling axis by sustaining appropriate ETV6/RUNX1 and STAT3 transcript levels in REH cells.

  14. The findings indicate that the tumor-suppressive roles of the let-7 family are antagonized by a potent and self-promoting triangle consisting of IGF2BP1 (potentially all IGF2BPs), LIN28B and HMGA2.

  15. The results from this study demonstrate the potential importance of the two-stem-loop motif as a target region for the inhibition of the CRD-BP-GLI1 RNA interaction and Hedgehog signaling pathway.

  16. these findings suggest that miR-150 functions as a tumor suppressor in Osteosarcoma (OS) partially by targeting IGF2BP1

  17. ETV6/RUNX1 transcript is a target of RNA-binding protein IGF2BP1 in t(12;21)(p13;q22)-positive acute lymphoblastic leukemia.

  18. Data show that ONECUT2, IGF2BP1, and ANXA2 proteins were confirmed to be microRNA-9 (miR-9) targets and aberrantly upregulated in hepatocellular carcinoma (HCC).

  19. The tumor-suppressive role of stromal IMP1 and its ability to modulate protumorigenic factors suggest that IMP1 status is important for the initiation and growth of epithelial tumors

  20. IGF2BP1 as a direct and functional target of miR-196b.

Mouse (Murine) Insulin-Like Growth Factor 2 MRNA Binding Protein 1 (IGF2BP1) interaction partners

  1. This study showed that Zipcode binding protein 1 (ZBP1) is an mRNA-binding protein that regulates the local translation of proteins, including actin, in the growth cone and is required for Shh-mediated axon guidance.

  2. The tumor-suppressive role of stromal IMP1 and its ability to modulate protumorigenic factors suggest that IMP1 status is important for the initiation and growth of epithelial tumors

  3. High CRD-BP expression is associated with Breast Tumor.

  4. Results identify IGF2BP1 as a critical translational regulator of cIAP1-mediated apoptotic resistance in rhabdomyosarcoma.

  5. This study demonstrate that ZBP1 and the phosphorylation of ZBP1 are required for attractive guidance of cortical neurons, and appropriate filopodial dynamics.

  6. IMP1 plays a role in regulating the packaging of MLV genomic RNA and can be used for improving production of retroviral vectors

  7. WAP-CRD-BP mice are a novel model for mammary neoplasia and might provide insights into human breast cancer biology.

  8. IMP-1 associates with HuD and G3BP-1 proteins in an RNA-dependent manner and binds directly to tau mRNA. We also show an RNA-dependent association between G3BP-1 and HuD proteins

Zebrafish Insulin-Like Growth Factor 2 MRNA Binding Protein 1 (IGF2BP1) interaction partners

  1. required during retinal ganglion cell axon outgrowth in vivo

  2. Two KH domains of CRD-BP are required for efficient binding to oncogenic mRNAs and for granule formation in zebrafish embryos.

IGF2BP1 Antigen Profile

Protein Summary

This gene encodes a member of the insulin-like growth factor 2 mRNA-binding protein family. The protein encoded by this gene contains four K homology domains and two RNA recognition motifs. It functions by binding to the mRNAs of certain genes, including insulin-like growth factor 2, beta-actin and beta-transducin repeat-containing protein, and regulating their translation. Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with IGF2BP1

  • insulin like growth factor 2 mRNA binding protein 1 (IGF2BP1) antibody
  • insulin-like growth factor 2 mRNA binding protein 1 (Igf2bp1) antibody
  • insulin-like growth factor 2 mRNA binding protein 1 (igf2bp1) antibody
  • AL024068 antibody
  • AW549074 antibody
  • CRD-BP antibody
  • Crdbp antibody
  • D030026A21Rik antibody
  • D11Moh40e antibody
  • D11Moh45 antibody
  • IGF2BP1 antibody
  • IMP-1 antibody
  • Imp1 antibody
  • Neilsen antibody
  • VICKZ1 antibody
  • wu:fi72a06 antibody
  • Zbp1 antibody
  • zgc:152963 antibody

Protein level used designations for IGF2BP1

insulin-like growth factor 2 mRNA binding protein 1 , IGF-II mRNA-binding protein 1 , IGF2 mRNA-binding protein 1 , IMP-1 , VICKZ family member 1 , ZBP-1 , insulin-like growth factor 2 mRNA-binding protein 1 , zip code-binding protein 1 , zipcode-binding protein 1 , coding region determinant-binding protein , coding region determinant binding protein , insulin-like growth factor 2, binding protein 1 , zipcode binding protein 1 , B-actin zipcode-binding protein 1 , insulin-like growth factor 2 binding protein 1 , rZBP-1 , zipcode-binding protein-1

GENE ID SPECIES
455198 Pan troglodytes
100018704 Monodelphis domestica
100055918 Equus caballus
395953 Gallus gallus
10642 Homo sapiens
491064 Canis lupus familiaris
516853 Bos taurus
140486 Mus musculus
303477 Rattus norvegicus
558182 Danio rerio
100620940 Sus scrofa
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