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ITM2A encodes a type II membrane protein that belongs to the ITM2 family. Additionally we are shipping ITM2A Proteins (3) and and many more products for this protein.
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The complete coding sequences of three porcine genes--RAB14, S35A3 and ITM2A were amplified and nucleotide sequence and tissue expression were analysed.
ITM2A might be a susceptibility gene for Graves disease in the Xq21.1 locus, and environmental factors, such as viral and bacterial infections, probably contribute to GD pathogenesis by interacting with the risk SNP rs3827440 mediating the regulation of ITM2A expression.
ITM2A is a new biomarker of poor prognosis in ovarian cancer and a novel tumor suppressor that induces cell cycle arrest, acts as a chemosensitizer, and has therapeutic potential for ovarian cancer.
The upregulated gene with the largest effect size in ankylosing spondylitis was ITM2A, which plays a role in activation of T cells. (Meta-analysis)
ITM2A expression is positively regulated by PKA-CREB signaling and ITM2A expression interferes with autophagic flux by interacting with vacuolar ATPase.
our results show one of the first links between phenotypic variation in a population sample and an XCI-escaping locus and pinpoint ITM2A as a potential contributor to the sexual dimorphism in height
Enhanced ITM2A expression inhibits chondrogenic differentiation of mesenchymal stem cells.
Itm2a knockdown is sufficient to rescue the inhibitory effects of lamin A WT and R482W mutant overexpression on 3T3-L1 differentiation.
Itm2a possesses diverse functional properties as evidenced by differential expression during odontogenesis.
Itm2a is a target gene of GATA-3 that plays a minimal role in regulating the development and function of T cells
Itm2a is not only expressed in adult muscle fibres but also in the satellite cells responsible for regeneration.
Results support the involvement of Itm2a in the early stages of chondrogenesis in vitro.
Both Itm2a and Itm2c were not detected in the epididymis and vas deferens during sexual maturation.
This gene encodes a type II membrane protein that belongs to the ITM2 family. Studies in mouse suggest that it may be involved in osteo- and chondrogenic differentiation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
integral membrane protein 2A
, integral membrane protein 2A a
, integral membrane protein 2A b
, Integral membrane protein 2A
, BRICHOS domain containing 2A