anti-Integrin alpha 5/beta 3 Antibodies

ITAGV encodes integrin alpha chain V.

Type
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    Primary antibodies
Antigen
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Reactivity
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Application
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Host
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Clonality
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Conjugate
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Isotype
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Format
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1 Product
ReactivityHuman, Mouse (Murine), Rat (Rattus)
Application FACS, IF (p)
Order details Cat. No. ABIN2808756
$442.20
100 μL
Plus shipping costs $45.00
Delivery in 14 to 21 Business Days
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Integrin alpha 5/beta 3 (ITGA5/ITGB3) Antigen Profile

Protein Summary

ITAGV encodes integrin alpha chain V. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The I-domain containing integrin alpha V undergoes post-translational cleavage to yield disulfide-linked heavy and light chains, that combine with multiple integrin beta chains to form different integrins. Among the known associating beta chains (beta chains 1,3,5,6, and 8\; 'ITGB1', 'ITGB3', 'ITGB5', 'ITGB6', and 'ITGB8'), each can interact with extracellular matrix ligands\; the alpha V beta 3 integrin, perhaps the most studied of these, is referred to as the Vitronectin receptor (VNR). In addition to adhesion, many integrins are known to facilitate signal transduction. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with ITGA5/ITGB3

  • integrin subunit alpha V (ITGAV) antibody
  • CD51 antibody
  • MSK8 antibody
  • VNRA antibody
  • VTNR antibody

Protein level used designations for ITGA5/ITGB3

antigen identified by monoclonal antibody L230 , integrin alpha-V , integrin alphaVbeta3 , integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51) , vitronectin receptor subunit alpha

GENE ID SPECIES
3685 Homo sapiens
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