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Function as an agonist of NF-kappa B activation through the orphan IL-1-receptor-related protein 2. Additionally we are shipping Interleukin 1 Family, Member 6 Antibodies (82) and Interleukin 1 Family, Member 6 Proteins (29) and many more products for this protein.
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Human IL1F6 ELISA Kit for Sandwich ELISA - ABIN841882
Ciccia, Accardo-Palumbo, Alessandro, Alessandri, Priori, Guggino, Raimondo, Carubbi, Valesini, Giacomelli, Rizzo, Triolo: Interleukin-36? axis is modulated in patients with primary Sjögren's syndrome. in Clinical and experimental immunology 2015
Show all 2 Pubmed References
The data identify a novel role for IL-36 signaling in colonic inflammation and indicate that the IL-36R (show IL1RL2 ELISA Kits) pathway may represent a novel target for therapeutic intervention.
IL-1 (show IL1A ELISA Kits) and IL-36 have roles as inflammatory mediators in pustular psoriasis in a mouse model
An essential role of C/EBPbeta (show CEBPB ELISA Kits) in the regulation of the Il36A gene via the proximal half-CRE*C/EBP (show CEBPA ELISA Kits) element in response to inflammatory stimuli.
IL-36alpha acts as a pro-inflammatory cytokine in the lungs independent of both IL-1alpha and IL-1beta (show IL1B ELISA Kits).
Interleukin-36 (IL-36) ligands require processing for full agonist (IL-36alpha, IL-36beta, and IL-36gamma) or antagonist (IL-36Ra) activity
A critical role of IL-36R (show IL1RL2 ELISA Kits) ligands in the interface between innate and adaptive immunity, leading to the stimulation of T helper responses.
Transcripts for IL-1F5, -1F6, -1F8, and -1F9 are all significantly increased in the involved skin of bitransgenic mice compared with their monotransgenic controls.
IL-1F6 can be externalized via a stimulus-coupled mechanism comparable to that used by IL-1beta (show IL1B ELISA Kits)
IL-36-mediated IL-6 (show IL6 ELISA Kits) and CXCL8 (show IL8 ELISA Kits) production in human lung fibroblasts and bronchial epithelial cells may be involved in pulmonary inflammation especially caused by bacterial or viral infections.
Data suggest that interleukin-36alpha (IL-36alpha) plays an important role in the pathophysiology of inflammation and fibrosis in the pancreas via an autocrine function.
Increased Expression of Interleukin-36 (show FIL1h ELISA Kits) is associated with Inflammatory Bowel Disease.
Study shows that plasma concentrations of IL-36alpha and IL-36gamma are overexpressed in active systemic lupus erythematosus patients and that IL-36alpha has a substantial pro-inflammatory effect through regulation of IL-6 (show IL6 ELISA Kits) and CXCL8 (show IL8 ELISA Kits) production.
IL36A-IL36R (show IL1RL2 ELISA Kits) axis is modulated in patients with primary Sjogren's syndrome.
Results show that IL-36alpha expression may play a pivotal role in determining the prognosis of hepatocellular carcinoma (HCC).
The novel cytokine interleukin-36alpha is expressed in psoriatic and rheumatoid arthritis synovium.
Interleukin-36 (show FIL1h ELISA Kits) (IL-36) ligands require processing for full agonist (IL-36alpha, IL-36beta, and IL-36gamma) or antagonist (IL-36Ra) activity
Expression of IL-1F6 is increased in human plaque psoriasis skin and in the lesional skin of transgenic mice compared with monotransgenic littermates.
Function as an agonist of NF-kappa B activation through the orphan IL-1-receptor-related protein 2. Could constitute part of an independent signaling system analogous to interleukin-1 alpha (IL-1A), beta (IL-1B) receptor agonist and interleukin-1 receptor type I (IL-1R1), that is present in epithelial barriers and takes part in local inflammatory response.
interleukin 1 family, member 6
, interleukin-1 family member 6
, interleukin 1 family, member 6 (epsilon)
, interleukin 1 family, member 6 (epsilon)-like
, FIL1 epsilon
, IL-1 epsilon
, interleukin 1 family, member 9
, interleukin-1 epsilon
, interleukin-1 homolog 1
, interleukin-36 alpha
, IL-1F6 (FIL-1-epsilon)
, interleukin 1, epsilon