Interleukin 31 Receptor A Proteins (IL31RA)

The protein encoded by IL31RA belongs to the type I cytokine receptor family. Additionally we are shipping Interleukin 31 Receptor A Antibodies (53) and Interleukin 31 Receptor A Kits (10) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
IL31RA 133396 Q8NI17
IL31RA 218624 Q8K5B1
Rat IL31RA IL31RA 688622  
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Top Interleukin 31 Receptor A Proteins at antibodies-online.com

Showing 6 out of 13 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$6,749.58
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$6,749.58
Details
Human Cells Human Fc Tag,ECD 50 μg Log in to see 14 to 16 Days
$250.80
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Escherichia coli (E. coli) Human His tag,T7 tag 100 μg Log in to see 15 to 18 Days
$749.00
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Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$414.29
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see Available
$814.00
Details

IL31RA Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , ,
, , , , ,
Mouse (Murine)
,

More Proteins for Interleukin 31 Receptor A (IL31RA) Interaction Partners

Human Interleukin 31 Receptor A (IL31RA) interaction partners

  1. The first demonstration of the involvement of the IL-31/IL-31R axis in cancer came from studies in patients with mycosis fungoides/Sezary syndrome, the most frequent, cutaneous T cell lymphoma. Tumor cells were shown to produce IL-31, whose serum levels correlated with pruritus intensity.

  2. The interleukin IL-31/IL-31receptor axis contributes to tumor growth in human follicular lymphoma.

  3. detected in keratinocytes and nerve fibers in the dermis of atopic dermatitis and in the neurons of normal dorsal root ganglia

  4. IL31RA is a functional receptor expressed by a small subpopulation of IL-31RA(+)/TRPV1(+)/TRPA1(+) neurons and is a critical neuroimmune link between TH2 cells and sensory nerves for the generation of T cell-mediated itch.

  5. IL-31 and IL-31RA are upregulated in patients with allergic rhinitis, and induce MUC5AC gene expression in human airway epithelial cells.

  6. IFN-gamma-induced IL-31RA upregulation in dermal microvascular endothelium is processed via JNK and PI3 kinase activation

  7. The identification of OSMR and IL31RA gene pathology provides an explanation of the high prevalence of primary cutaneous amyloidosis in Taiwan as well as new insight into disease pathophysiology.

  8. A novel type I cytokine receptor is expressed on monocytes, signals proliferation, and activates STAT-3 and STAT-5.

  9. GPL is a novel cytokine receptor related to GP130 and leukemia inhibitory factor receptor

  10. the molecular mechanisms underlying GPL-mediated signal transduction

  11. IL-31 receptor alpha expression in epidermal keratinocytes is modulated by cell differentiation and interferon gamma

  12. ). Binding of IL-31 to its receptor activates Jak/STAT, PI3K/AKT and MAPK pathways.[review]

Mouse (Murine) Interleukin 31 Receptor A (IL31RA) interaction partners

  1. IL-31 upregulates IL-31RA expression in DRG neuron cell bodies, and cutaneous-injected IL-31-induced itching is enhanced by DRG IL-31RA expression in mice

  2. Anti-IL-31 receptor antibody is shown to be a potential therapeutic option for treating itch and dermatitis in mice

  3. IL31RA is a functional receptor expressed by a small subpopulation of IL-31RA(+)/TRPV1(+)/TRPA1(+) neurons and is a critical neuroimmune link between TH2 cells and sensory nerves for the generation of T cell-mediated itch.

  4. Gp130(757F/F) mice rapidly develop distal stomach tumors, with loss of SHP2/Erk/AP-1 transcriptional regulation exemplified by decreased TFF1 expression and increased STAT1/3 regulated genes such as Reg I.

  5. IL-31 receptor alpha signaling is a novel negative regulatory pathway that specifically limits T helper cell type 2 inflammation.

  6. these data provide the first evidence of a function for IL-31-IL-31R interactions in limiting the magnitude of type 2 inflammatory responses within the intestine.

Interleukin 31 Receptor A (IL31RA) Protein Profile

Protein Summary

The protein encoded by this gene belongs to the type I cytokine receptor family. This receptor, with homology to gp130, is expressed on monocytes, and is involved in IL-31 signaling via activation of STAT-3 and STAT-5. It functions either as a monomer, or as part of a receptor complex with oncostatin M receptor (OSMR). Several alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

Gene names and symbols associated with IL31RA

  • interleukin 31 receptor A (IL31RA)
  • interleukin 31 receptor A (Il31ra)
  • CRL protein
  • CRL3 protein
  • GLM-R protein
  • Glmr protein
  • GPL protein
  • hGLM-R protein
  • IL-31RA protein
  • IL31RA protein
  • NR10 protein
  • PLCA2 protein
  • PRO21384 protein

Protein level used designations for IL31RA

interleukin 31 receptor A , gp130-like monocyte receptor , IL-31 receptor subunit alpha , IL-31R subunit alpha , class I cytokine receptor , cytokine receptor-like 3 , interleukin-31 receptor subunit alpha , soluble type I cytokine receptor CRL3 , zcytoR17 , IL-31R-alpha , IL-31RA , cytokine receptor NR10 , gp130-like receptor , interleukin 31RA , mGLM-R , novel cytokine receptor 10

GENE ID SPECIES
471545 Pan troglodytes
487212 Canis lupus familiaris
522636 Bos taurus
133396 Homo sapiens
218624 Mus musculus
688622 Rattus norvegicus
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