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Functions in mitochondrial tRNA maturation. Additionally we are shipping KIAA0391 Antibodies (30) and many more products for this protein.
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This study presents the crystal structure of human MRPP3, which features a remarkably distorted and hence non-productive active site that authors propose will switch to a fully productive state only upon association with MRPP1 (show RG9MTD1 Proteins), MRPP2 (show HSD17B10 Proteins) and pre-tRNA substrate.
using a genome-wide association study, found that posttranscriptional modification of functionally important sites in mitochondrial transfer RNAs (tRNAs) is under strong genetic control, largely driven by a missense mutation in MRPP3
Inhibition of mitochondrial RNase P by beta-amyloid is an unspecific effect and is not mediated by beta-amyloid interaction with SDR5C1 (show HSD17B10 Proteins).
Haplotypes in KIAA0391 and PSMA6 (show PSMA6 Proteins) genes is a genetic link for myocardial infarction and coronary artery disease.
Functions in mitochondrial tRNA maturation. Part of mitochondrial ribonuclease P, an enzyme composed of MRPP1/RG9MTD1, MRPP2/HSD17B10 and MRPP3/KIAA0391, which cleaves tRNA molecules in their 5'-ends (By similarity).
mitochondrial RNase P protein 3
, mitochondrial RNase P subunit 3
, mitochondrial ribonuclease P protein 3
, proteinaceous RNase P