anti-Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 3 (KIR2DL3) Antibodies

Receptor on natural killer (NK) cells for HLA-C alleles (HLA-Cw1, HLA-Cw3 and HLA-Cw7). Additionally we are shipping KIR2DL3 Proteins (15) and KIR2DL3 Kits (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
KIR2DL3 3804 P43628
KIR2DL3    
KIR2DL3    
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Top anti-KIR2DL3 Antibodies at antibodies-online.com

Showing 10 out of 147 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse Fluorescein FACS Detection of KIR2DL3/CD158b2 in Human PBMCs by Flow Cytometry. Human peripheral blood mononuclear cells (PBMCs) were stained with Mouse Anti-Human KIR2DL3/CD158b2 Fluorescein-conjugated Monoclonal Antibody. 100 Tests Log in to see 8 to 9 Days
$265.55
Details
Human Mouse PE FACS Detection of KIR2DL3/CD158b2 in Human PBMCs by Flow Cytometry. Human peripheral blood mononuclear cells (PBMCs) were stained with Mouse Anti-Human KIR2DL3/CD158b2 PE-conjugated Monoclonal Antibody. 100 Tests Log in to see 8 to 9 Days
$319.79
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated ELISA, FACS, ICC, IF, WB Western Blot: KIR2DL3/CD158b2 Antibody (190IIC311) [NBP1-04316] - The Recombinant Proteins (50ng) were resolved by SDS PAGE, transferred to PVDF membrane and probed with anti human KIR2DL3 antibody (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. Lane 1.: KIR2DL1 recombinant protein Lane 2.: KIR2DL3 recombinant protein Lane 3.: KIR2DS4 recombinant protein 0.1 mL Log in to see 12 to 15 Days
$418.10
Details
Human Mouse APC FACS Detection of KIR2DL3/CD158b2 in Human PBMCs by Flow Cytometry. Human peripheral blood mononuclear cells (PBMCs) were stained with Mouse Anti-Human KIR2DL3/CD158b2 APC-conjugated Monoclonal Antibody. 100 Tests Log in to see 8 to 9 Days
$363.86
Details
Human Mouse Un-conjugated CyTOF, FACS   500 μg Log in to see 8 to 9 Days
$323.18
Details
Human Rabbit Un-conjugated ELISA, IHC, WB Western blot analysis of extracts of liver, using KIR2DL3 antibody. The lane on the left is treated with the antigen-specific peptide. ABIN6276824 at 1/100 staining Human liver cancer tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22¡ãC. An HRP conjugated goat anti-rabbit antibody was used as the secondary 100 μL Log in to see 11 to 12 Days
$390.77
Details
Human Mouse Un-conjugated FACS, IP, WB   0.2 mg Log in to see 6 to 8 Days
$654.50
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded human rectal carcinoma labeled with Anti-CD158b2 Polyclonal Antibody, Unconjugated (ABIN748448) at 1:200 followed by conjugation to the secondary antibody and DAB staining. Formalin-fixed and paraffin embedded mouse colon labeled with Anti-CD158b2 Polyclonal Antibody, Unconjugated (ABIN748448) at 1:200 followed by conjugation to the secondary antibody and DAB staining. 100 μL Log in to see 3 to 7 Days
$329.45
Details
Human Mouse APC ELISA, WB 100 Tests Log in to see 10 to 12 Days
$280.77
Details

Top referenced anti-KIR2DL3 Antibodies

  1. Human Monoclonal KIR2DL3 Primary Antibody for CyTOF, FACS - ABIN4900804 : Horowitz, Guethlein, Nemat-Gorgani, Norman, Cooley, Miller, Parham: Regulation of Adaptive NK Cells and CD8 T Cells by HLA-C Correlates with Allogeneic Hematopoietic Cell Transplantation and with Cytomegalovirus Reactivation. in Journal of immunology (Baltimore, Md. : 1950) 2015 (PubMed)
    Show all 7 Pubmed References

  2. Human Monoclonal KIR2DL3 Primary Antibody for FACS - ABIN4898680 : Ordóñez, Gómez-Lozano, Rosales, Vilches: Molecular characterisation of KIR2DS2*005, a fusion gene associated with a shortened KIR haplotype. in Genes and immunity 2011 (PubMed)
    Show all 7 Pubmed References

  3. Human Monoclonal KIR2DL3 Primary Antibody for FACS - ABIN4898682 : Yu, Mitsui, Wei, Mao, Butchar, Shah, Zhang, Mishra, Alvarez-Breckenridge, Liu, Liu, Yokohama, Trotta, Marcucci, Benson, Loughran, Tridandapani, Caligiuri: NKp46 identifies an NKT cell subset susceptible to leukemic transformation in mouse and human. in The Journal of clinical investigation 2011 (PubMed)
    Show all 5 Pubmed References

  4. Human Monoclonal KIR2DL3 Primary Antibody for FACS - ABIN2688999 : Cambiaggi, Orengo, Meazza, Sforzini, Tazzari, Lauria, Raspadori, Zambello, Semenzato, Moretta, Ferrini: The natural killer-related receptor for HLA-C expressed on T cells from CD3+ lymphoproliferative disease of granular lymphocytes displays either inhibitory or stimulatory function. in Blood 1996 (PubMed)
    Show all 4 Pubmed References

  5. Human Monoclonal KIR2DL3 Primary Antibody for FACS - ABIN4898676 : Eller, Koehler, Kijak, Eller, Guwatudde, Marovich, Michael, de Souza, Wabwire-Mangen, Robb, Currier, Sandberg: Human immunodeficiency virus type 1 infection is associated with increased NK cell polyfunctionality and higher levels of KIR3DL1+ NK cells in ugandans carrying the HLA-B Bw4 motif. in Journal of virology 2011 (PubMed)
    Show all 3 Pubmed References

  6. Human Polyclonal KIR2DL3 Primary Antibody for IF (p), IHC (p) - ABIN748448 : Mozer-Lisewska, Mania, Kowala-Piaskowska, Kluk, Samara, Pauli, ?eromski: Detection and significance of cytotoxic cell subsets in biopsies of HCV-infected human livers. in Archivum immunologiae et therapiae experimentalis 2014 (PubMed)

  7. Human Monoclonal KIR2DL3 Primary Antibody for FACS, WB - ABIN2478646 : Westhof, Flossmann, Müller: The action of ionizing radiation on protein: radical formation in L-histidine crystals. in International journal of radiation biology and related studies in physics, chemistry, and medicine 1975 (PubMed)
    Show all 2 Pubmed References

More Antibodies against KIR2DL3 Interaction Partners

Human Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 3 (KIR2DL3) interaction partners

  1. These results suggest a detrimental role of HLA-A-Bw4 and HLA-C2 groups, which are associated with the development of chronic hepatitis B, and a protective role of KIR2DL3.

  2. A minority (21%) of HLA-B( *)46:01 peptides, with common C-terminal characteristics, form ligands for KIR2DL3.

  3. KIR 2D (L1, L3, L4, S4) and KIR 3DL1 expression was correlated with poor prognosis in non-small cell lung carcinoma patients.

  4. CD16+ cells were significantly more frequent among Natural Killer (NK) cells negative for the inhibitory KIR (iKIR) KIR2DL1, KIR2DL3, and KIR3DL1 than those positive for any one of these iKIR to the exclusion of the others, making iKIR+ NK cells poorer antibody dependent cellular cytotoxicity effectors than iKIR- NK cells.

  5. These results show that 2DL3(+) NK cells are mediators of HIV-specific responses. Furthermore, responses of NK cell populations to iCD4 are influenced not only by NK cell education through specific KIR/HLA pairs, but also by differential HIV-mediated changes in HLA expression.

  6. Results identified three SNPs (S320F, H245Y, and H77Y) as highly deleterious in KIR2DL3 and nine SNPs (R157Q, H156Y, S63L, R157 W, F179 V, H128R, T101 M, R180C and F176I) in case of IFNL3, in coding region only with high conservation ranks highlighting the functional SNPs on phenotypic variability and disease susceptibility on HCV clearance candidate genes.

  7. KIR2DL2/KIR2DL3-glutamate(35) alleles are functionally stronger than -glutamine(35) alleles.

  8. KIR2DL2/2DS2-C1C1 genotype is associated with type 1 diabetes in Saudi children

  9. gene polymorphism is associated with Crohn's disease in Spanish patients

  10. study compared KIR gene repertoire of HIV-1 positive with exposed uninfected (EU)) infants to elucidate its association with transmission; results revealed presence of significantly high frequencies of activating gene KIR 2DS5 and inhibitory gene KIR 2DL3 in EU infants as compared to HIV-1 positive infants

  11. genetic association study in population in Eastern India: Data suggest that interactions between KIRs (KIR2DL2, KIR2DS4, KIR2DL3) and HLA ligands (HLAC1, HLAC2) contribute significantly toward susceptibility and protection toward type 1 diabetes.

  12. Allelic polymorphism of KIR2DL2/2DL3 in a southern Chinese population.

  13. The authors have identified a deleterious effect of the KIR2DL3-HLA-C1 receptor-ligand combination on HIV clinical outcomes in a Thai cohort.

  14. Single Nucleotide Polymorphism in KIR2DL3 gene is associated with Asthma and Atopic Dermatitis.

  15. KIR2DL3 has previously been identified as important for clearance of the Hepatitis C virus after established infection,not found to be relevant to resistance to Hepatitis C infection.

  16. Genetic risk for co-occurrence of type 1 diabetes and celiac disease is modified by HLA-C and killer immunoglobulin-like receptors.

  17. CD4(+) CD28(-) cells exhibited increased KIR2DS2, reduced KIR2DL3 and increased DAP12 expression in HD-ESRD compared with NDD-CKD patients.

  18. Authors showed an increase in HLA-C1/KIR2DL2 and HLA-C1/KIR2DL3 pairs in human papillomavirus high-risk infected patients (OR 3.05, 3.24) with invasive cervical cancer (OR 1.33, 3.68).

  19. KIR2DL3-positive NK cells were more sensitive to changes in the peptide content of MHC class I than KIR2DL2-positive NK cells.

  20. these results suggest that inhibitory KIR2DL2 and KIR2DL3, which are alleles of the same locus, play a role in the inverse effects on PM and PM/HIV co-infection

KIR2DL3 Antigen Profile

Protein Summary

Receptor on natural killer (NK) cells for HLA-C alleles (HLA-Cw1, HLA-Cw3 and HLA-Cw7). Inhibits the activity of NK cells thus preventing cell lysis.

Gene names and symbols associated with KIR2DL3

  • killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 3 (KIR2DL3) antibody
  • CD158b antibody
  • CD158B2 antibody
  • GL183 antibody
  • KIR-023GB antibody
  • KIR-K7b antibody
  • KIR-K7c antibody
  • KIRCL23 antibody
  • NKAT antibody
  • NKAT2 antibody
  • NKAT2A antibody
  • NKAT2B antibody
  • p58 antibody

Protein level used designations for KIR2DL3

CD158 antigen-like family member B2 , MHC class I NK cell receptor , NK-receptor , NKAT-2 , killer cell immunoglobulin-like receptor 2DL3 , killer inhibitory receptor cl 2-3 , natural killer associated transcript 2 , natural killer cell inhibitory receptor KIR2DL3 , natural killer-associated transcript 2 , p58 NK receptor CL-6 , p58 natural killer cell receptor clone CL-6 , p58.2 MHC class-I specific NK receptor , p58.2 MHC class-I-specific NK receptor

GENE ID SPECIES
3804 Homo sapiens
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